Publications
Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response
Benedikt Simbrunner, Esther Caparrós, Teresa Neuwirth, Philipp Schwabl, Philipp Königshofer, David Bauer, Rodrig Marculescu, Michael Trauner, Bernhard Scheiner, Georg Stary, Mattias Mandorfer, Thomas Reiberger, Rubén Francés.Hepatol Int. 2023 Mar 7. doi: 10.1007/s12072-023-10496-y. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36881247/
Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers
Ines Bojanic, Nina Worel, Carolina P Pacini, Georg Stary, Agnieszka Piekarska, Aisling M Flinn, Kimberly J Schell, Andrew R Gennery, Robert Knobler, João F Lacerda, Hildegard T Greinix, Drazen Pulanic, Rachel E Crossland.Front Immunol. 2023 Feb 17;14:1086006. doi: 10.3389/fimmu.2023.1086006. eCollection 2023.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36875063/
Polymerase-δ-deficiency as a novel cause of inborn cancer predisposition associated with human papillomavirus infection
Johanna Strobl, Bettina Huber, Raul Jimenez Heredia, Reinhard Kirnbauer, Kaan Boztug, Georg Stary.Br J Dermatol. 2023 Feb 14:ljad021. doi: 10.1093/bjd/ljad021. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36787285/
Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer
Nadine Bayer, Bela Hausmann, Ram Vinay Pandey, Florian Deckert, Laura-Marie Gail, Johanna Strobl, Petra Pjevac, Christoph Krall, Luisa Unterluggauer, Anna Redl, Victoria Bachmayr, Lisa Kleissl, Marion Nehr, Rasmus Kirkegaard, Athanasios Makristathis, Martin L Watzenboeck, Robert Nica, Clement Staud, Lukas Hammerl, Philipp Wohlfarth, Rupert C Ecker, Sylvia Knapp, Werner Rabitsch, David Berry, Georg Stary.Leukemia. 2023 Mar;37(3):724. doi: 10.1038/s41375-023-01839-7.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36788337/
In vivo screening unveils pervasive RNA-binding protein dependencies in leukemic stem cells and identifies ELAVL1 as a therapeutic target
Ana Vujovic, Laura de Rooij, Ava Keyvani Chahi, He Tian Chen, Brian A Yee, Sampath K Loganathan, Lina Liu, Derek C H Chan, Amanda Tajik, Emily Tsao, Steven Moreira, Pratik Joshi, Joshua Xu, Nicholas Wong, Zaldy Balde, Soheil Jahangiri, Sasan Zandi, Stefan Aigner, John E Dick, Mark D Minden, Daniel Schramek, Gene W Yeo, Kristin J Hope.Blood Cancer Discov. 2023 Feb 10:BCD-22-0086. doi: 10.1158/2643-3230.BCD-22-0086. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36763002/
Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation
Thomas Krausgruber, Anna Redl, Daniele Barreca, Konstantin Doberer, Daria Romanovskaia, Lina Dobnikar, Maria Guarini, Luisa Unterluggauer, Lisa Kleissl, Denise Atzmüller, Carolina Mayerhofer, Aglaja Kopf, Simona Saluzzo, Clarice X Lim, Praveen Rexie, Thomas Weichhart, Christoph Bock, Georg Stary.Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36750099/
Macrophage and monocyte subsets as new therapeutic targets in cancer immunotherapy
B Fendl, A S Berghoff, M Preusser, B Maier.ESMO Open. 2023 Feb;8(1):100776. doi: 10.1016/j.esmoop.2022.100776. Epub 2023 Feb 1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36731326/
A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
Patrick Essletzbichler, Vitaly Sedlyarov, Fabian Frommelt, Didier Soulat, Leonhard X Heinz, Adrijana Stefanovic, Benedikt Neumayer, Giulio Superti-Furga.Life Sci Alliance. 2023 Feb 1;6(4):e202201715. doi: 10.26508/lsa.202201715. Print 2023 Apr.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36725334/
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence
Miquel Duran-Frigola, Marko Cigler, Georg E Winter.J Am Chem Soc. 2023 Feb 8;145(5):2711-2732. doi: 10.1021/jacs.2c11098. Epub 2023 Jan 27.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36706315/
LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data
Peter Peneder, Christoph Bock, Eleni M Tomazou.Bioinform Adv. 2022 Mar 23;2(1):vbac017. doi: 10.1093/bioadv/vbac017. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36699368/
Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation
Ram Vinay Pandey, Johanna Strobl, Anna Redl, Luisa Unterluggauer, Laura Gail, Lisa Kleissl, Sophie Müller, Denise Atzmüller, Victoria Fife-Gernedl, Thomas Krausgruber, Hanna Knaus, Margit Mitterbauer, Philipp Wohlfarth, Werner Rabitsch, Christoph Bock, Georg Stary.Clin Immunol. 2023 Mar;248:109245. doi: 10.1016/j.clim.2023.109245. Epub 2023 Jan 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36702179/
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species
Johanna Klughammer, Daria Romanovskaia, Amelie Nemc, Annika Posautz, Charlotte A Seid, Linda C Schuster, Melissa C Keinath, Juan Sebastian Lugo Ramos, Lindsay Kosack, Ann Evankow, Dieter Printz, Stefanie Kirchberger, Bekir Ergüner, Paul Datlinger, Nikolaus Fortelny, Christian Schmidl, Matthias Farlik, Kaja Skjærven, Andreas Bergthaler, Miriam Liedvogel, Denise Thaller, Pamela A Burger, Marcela Hermann, Martin Distel, Daniel L Distel, Anna Kübber-Heiss, Christoph Bock.Nat Commun. 2023 Jan 16;14(1):232. doi: 10.1038/s41467-022-34828-y.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36646694/
Dual redox-active porous polyimides as high performance and versatile electrode material for next-generation batteries
Nicolas Goujon, Marianne Lahnsteiner, Daniel A Cerrón-Infantes, Hipassia M Moura, Daniele Mantione, Miriam M Unterlass, David Mecerreyes.Mater Horiz. 2023 Mar 6;10(3):967-976. doi: 10.1039/d2mh01335e.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36633135/
Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension
Bradley M Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane Vr Hütter, William M Oldham, Jörg Menche, Matthew L Steinhauser, Bradley A Maron.JCI Insight. 2023 Feb 22;8(4):e163932. doi: 10.1172/jci.insight.163932.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36626231/
Apoptosis as a Barrier against CIN and Aneuploidy
Johannes G Weiss, Filip Gallob, Patricia Rieder, Andreas Villunger.Cancers (Basel). 2022 Dec 21;15(1):30. doi: 10.3390/cancers15010030.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36612027/
The 2000HIV study: Design, multi-omics methods and participant characteristics
Wilhelm A J W Vos, Albert L Groenendijk, Marc J T Blaauw, Louise E van Eekeren, Adriana Navas, Maartje C P Cleophas, Nadira Vadaq, Vasiliki Matzaraki, Jéssica C Dos Santos, Elise M G Meeder, Janeri Fröberg, Gert Weijers, Yue Zhang, Jingyuan Fu, Rob Ter Horst, Christoph Bock, Rainer Knoll, Anna C Aschenbrenner, Joachim Schultze, Linos Vanderkerckhove, Talent Hwandih, Elizabeth R Wonderlich, Sai V Vemula, Mike van der Kolk, Sterre C P de Vet, Willem L Blok, Kees Brinkman, Casper Rokx, Arnt F A Schellekens, Quirijn de Mast, Leo A B Joosten, Marvin A H Berrevoets, Janneke E Stalenhoef, Annelies Verbon, Jan van Lunzen, Mihai G Netea, Andre J A M van der Ven.Front Immunol. 2022 Dec 20;13:982746. doi: 10.3389/fimmu.2022.982746. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36605197/
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter.J Am Chem Soc. 2023 Jan 18;145(2):1176-1184. doi: 10.1021/jacs.2c10784. Epub 2023 Jan 5.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36602777/