Skip to main content
The study authors Nikolaus Fortelny & Christoph Bock

Ready and Vigilant: Immune Cells on Standby

When pathogens invade the body, the immune system must react immediately to prevent or contain an infection. But how do our defence cells stay ready when no attacker is in sight? Scientists from Vienna have found a surprising explanation: They are constantly stimulated by healthy tissue. This keeps them active and ready to respond to pathogens. Based on this insight, future medications could be devised to selectively enhance our immune system’s attention. The study has been published in the journal Nature Immunology (DOI: 10.1038/s41590-024-01804-1).

Communication is crucial in immune defence. When a virus infects a cell, the cell releases…

Read more

CeMM Research Report 2023: On the path to utopia

We would like to present you the CeMM Research Report 2023 dedicated to: on the path to Utopia in research. It represents our endeavour to embrace the joy of dreaming and visualizing the future.

What does the future hold? We have embarked on a journey to envision the future, going beyond traditional planning to truly 'dream it up'. Inspired by the EU-LIFE Utopia Conference in Lisbon in 2023, we posed this question to the CeMM community, inviting anyone interested to translate their vision of CeMM's various aspects and spaces into graphics for the 2023 Research Report. Several accepted the challenge. Principal Investigator André Rendeiro, who…

Read more

Light Show in Living Cells: New method allows simultaneous fluorescent labelling of many proteins

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge - especially in living cells, as the required fluorescent labelling had to be individually attached to each protein. The research group led by Stefan Kubicek at CeMM has now overcome this hurdle: With a method called "vpCells," it is possible to label many proteins simultaneously, using five different fluorescent colours. This automated high-throughput approach, aided by AI-assisted image recognition, opens up entirely new applications in various disciplines, from fundamental cell biology to drug…

Read more

ERC Advanced Grant for CeMM Adjunct PI Nuno Maulide

We congratulate Nuno Maulide, CeMM Adjunct PI and Professor at the University of Vienna, for receiving the ERC Advanced Grant - which makes him one of the very few people in Europe who have won all the European Research Council grants in a row (ERC Starting Grant in 2011, ERC Consolidator Grant in 2016, ERC Proof of Concept Grant in 2018 and 2023). 

In his new ERC project "C-HANCE" hosted by the University of Vienna, Nuno Maulide explores the reactivity of positively charged carbon atoms (known as carbocations). Although many reactions involving carbocations are fundamental to organic chemistry - parts of which are even taught in basic…

Read more
EU-LIFE Charter Principles. Figure by the EU-LIFE Office.

EU-LIFE Charter of Independent Life Science Research Institutes

CeMM is a proud member of the EU-LIFE alliance since the beginning, and Giulio Superti-Furga, Scientific Director of CeMM and the Ri.MED Foundation, is the current Chair of EU-LIFE. The 15 EU-LIFE member institutes are leading and renowned life science research centers in Europe, and are profiting from the exchange of best practices, having common principles of research excellence, and contributing to European research policy. The different activities of the alliance are carried out by the Board of Directors and dedicated working groups, formed by experts and main representatives from the member institutions. They are supported by Marta…

Read more
Oleksandr Petrenko (l) and Thomas Reiberger (r) © Anna Yuwen / CeMM

New Insights Could Improve Treatment of Liver Fibrosis

Repeated or chronic liver injury, for example by viral hepatitis or alcohol consumption, triggers a complicated molecular process of scaring called liver fibrosis. Researchers at CeMM and MedUni Vienna have now succeeded in better understanding this process in a new study by examining gene activities at various stages of the liver disease. Their findings could contribute to a first-time therapy for fibrosis.

The liver is not only the largest internal organ but also vital for human life as a metabolic center. It also possesses remarkable self-healing powers: even when large portions are removed, such as during surgery, they quickly regenerate…

Read more
F.l.t.r.: Jürgen A. Knoblich (IMBA), Gaia Novarino (ISTA), Christoph Bock (CeMM),
Igor Igorevich Adameyko (MedUni Vienna),
Roman A. Romanov (MedUni Vienna), Daniela D. Pollak-Monje Quiroga (MedUni Vienna) © FWF/Klaus Ranger

FWF "Emerging Fields" Grant for Brain Resilience

We congratulate the Consortium of the newly funded "Brain Resilience" grant! CeMM PI Christoph Bock is part of a team of world-renowned scientists that received one of the first "Emerging Fields" grants of the Austrian Science Fund (FWF). Over five years, the research groups coordinated by Igor Adameyko, MedUni Vienna will receive up to 6 million Euro to investigate brain resilience against disease.  

The brain of mammals is formed through highly complex developmental processes, controlled by thousands of genes and their interaction with the prenatal environment. Mutations in the underlying genes can predispose individuals to various…

Read more
Georg Winter

Georg Winter joins global Cancer Grand Challenges team taking on solid tumours in children

The team, which is co-led by Martin Eilers of the University of Würzburg, Germany, and Yaël Mossé of Children’s Hospital of Philadelphia, US, will receive up to $25m over five years to take on the challenge of solid tumours in children.

A global, interdisciplinary team of researchers, including CeMM PI Georg Winter, has been selected to receive a Cancer Grand Challenges award of up to $25m over five years to tackle the solid tumours in children challenge. The Cancer Grand Challenges KOODAC team is co-led by Martin Eilers of the University of Würzburg, Germany, and Yaël Mossé of Children’s Hospital of Philadelphia, US.

Cancer Grand…

Read more
Giulio Superti-Furga (c) Bubu Dujmic/CeMM

Giulio Superti-Furga awarded the Austrian Cross of Honour for Science and Art, First Class

On 26 February 2024, Giulio Superti-Furga had the pleasure and honor to receive the Austrian Cross of Honour for Science and Art, First Class (Österreichisches Ehrenkreuz I. Klasse für Wissenschaft und Kunst) from the Austrian President Professor Alexander Van der Bellen.

The Austrian Cross of Honour for Science and Art, First Class is awarded based on the recommendation of the Federal Government. Established in 1955, this Austrian state decoration recognizes both, Austrians and leading foreign figures who have distinguished themselves and earned general acclaim through especially superior creative and commendable services in the areas of…

Read more
Georg Winter (left) and Matthias Hinterndorfer (right) © CeMM/Anna Yuwen

New System Triggers Cellular Waste Disposal

Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers at CeMM have already demonstrated the efficacy of this approach through two distinct methods. Now, in collaboration with colleagues from the University of Dundee in Scotland, they unveil a third system capable of targeting and disposing of previously inaccessible proteins. Their groundbreaking findings have been published in the journal Nature.


Read more