C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, IH Kaltheuner, E Hahn, K Seiler, A Koren, G Petzold, M Fellner, C Bock, AC Müller, J Zuber, M Geyer, NH Thomä, S Kubicek, G E Winter. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32747809/

Ghosh S, Köstel Bal S, Edwards E S J, Pillay B, Jimenez-Heredia R, Rao G, Erol Cipe F, Salzer E, Zoghi S, Abolhassani H, Momen T, Gostick E, Price D A, Zhang Y, Oler A J, Gonzaga-Jauregui C, Erman B, Metin A, Ilhan I, Haskologlu S, Islamoglu C, Baskin K, Ceylaner S, Yilmaz E, Unal E, Karakukcu M, Berghuis D, Cole T, Kumar Gupta A, Hauck F, Hoepelman A, Baris S, Karakoc-Aydiner E, Ozen A, Kager L, Holzinger D, Paulussen M, Krüger, R, Meisel R, Thomas Oommen P, Morris E C, Neven B, Worth A J J, van Montfrans J M, Fraaij P, Choo S, Dogu F, Davies E G, Burns S, Dueckers G, Perez Becker R, von Bernuth H, Latour S, Faraci M, Gattorno M, Su H, Pan-Hammarström, Q, Hammarström L, Lenardo M J, Ma C S, Niehues T, Aghamohammadi A, Rezaei N, Ikinciogullari A, Tangye S G, Lankester A C, Boztug K. Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency. Blood. 2020 Dec 3;136(23):2638-2655. Doi: 10.1182/blood.2020006738.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32603431/

Girardi E, César-Razquin A, Lindinger S, Papakostas K, Konecka J, Hemmerich J, Kickinger S, Kartnig F, Gürtl B, Klavins K, Sedlyarov V, Ingles-Prieto A, Fiume G, Koren A, Lardeau CH, Kumaran Kandasamy R, Kubicek S, Ecker GF, Superti-Furga G. A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs. Nat Chem Biol. 2020 Apr;16(4):469-478. doi: 10.1038/s41589-020-0483-3. Epub 2020 Mar 9.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32152546

Marquina-Sanchez B, Fortelny N, Farlik M, Vieira A, Collombat P, Bock C, Kubicek S. Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets. Genome Biol. 2020 May 6;21(1):106. doi: 10.1186/s13059-020-02006-2.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32375897

Rendeiro AF, Krausgruber T, Fortelny N, Zhao F, Penz T, Farlik M, Schuster LC, Nemc A, Tasnády S, Réti M, Mátrai Z, Alpár D, Bödör C, Schmidl C, Bock C. Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL. Nat Commun. 2020 Jan 29;11(1):577. doi: 10.1038/s41467-019-14081-6.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31996669

Akgün M, Ünal AB, Ergüner B, Pfeifer N, Kohlbacher O. Identifying Disease-Causing Mutations with Privacy Protection. Bioinformatics. 2020 Jul 19;36(21):5205–13. doi: 10.1093/bioinformatics/btaa641. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32683440/

Ali OH, Bomze D, Risch L, Brugger SD, Paprotny M, Weber M, Thiel S, Kern L, Albrich WC, Kohler P, Kahlert CR, Vernazza P, Bühler PK, Schüpbach RA, Gómez-Mejia A, Popa AM, Bergthaler A, Penninger JM, Flatz L. Severe COVID-19 is associated with elevated serum IgA and antiphospholipid IgA-antibodies. Clin Infect Dis. 2020 Sep 30;ciaa1496. doi: 10.1093/cid/ciaa1496. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32997739/

Alm E, Broberg EK, Connor T, Hodcroft EB, Komissarov AB, Maurer-Stroh S, Melidou A, Neher RA, O'Toole A, Pereyaslov D, WHO European Region sequencing laboratories and GISAID EpiCoV group; WHO European Region sequencing laboratories and GISAID EpiCoV group*. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveill. 2020 Aug;25(32):2001410. doi: 10.2807/1560-7917.ES.2020.25.32.2001410.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32794443/

Balligand T, Achouri Y, Pecquet C, Gaudray G, Colau D, Hug E, Rahmani Y, Stroobant V, Plo I, Vainchenker W, Kralovics R, Van den Eynde BJ, Defour JP, Constantinescu SN. Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development. Leukemia. 2020 Feb;34(2):510-521. doi: 10.1038/s41375-019-0538-1. Epub 2019 Aug 30.
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Bensimon A, Pizzagalli MD, Kartnig F, Dvorak V, Essletzbichler P, Winter GE, Superti-Furga G. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020 Jun 18;27(6):728-739.e9. doi: 10.1016/j.chembiol.2020.04.003. Epub 2020 May 7.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32386596/

Boehm T, Hubmann H, Petroczi K, Mathis D, Klavins K, Fauler G, Plecko B, Struys E, Jilma B. Condensation of delta-1-piperideine-6-carboxylate with ortho-aminobenzaldehyde allows its simple, fast, and inexpensive quantification in the urine of patients with antiquitin deficiency. J Inherit Metab Dis. 2020 Jul;43(4):891-900. doi: 10.1002/jimd.12214. Epub 2020 Jan 29.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31930735/

Boehm T, Karer M, Gludovacz E, Petroczi K, Resch M, Schuetzenberger K, Klavins K, Borth N, Jilma B. Simple, sensitive and specific quantification of diamine oxidase activity in complex matrices using newly discovered fluorophores derived from natural substrates. Inflamm Res. 2020 Sep;69(9):937-950. doi: 10.1007/s00011-020-01359-5. Epub 2020 Jun 1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32488317/

Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33199895/

Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G. Environmental arginine controls multinuclear giant cell metabolism and formation. Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31969567/

Brunner SB, Marculescu R, Scheiner B, Schwabl P, Bucsics T, Stadlmann A, Bauer DJM, Paternostro R, Eigenbauer E, Pinter M, Stättermayer AF, Trauner M, Mandorfer M, Reiberger T. Non-invasive detection of portal hypertension by enhanced liver fibrosis score in patients with different aetiologies of advanced chronic liver disease. Liver Int. 2020 May 2. doi: 10.1111/liv.14498. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32358998

Brusilovskaya K, Königshofer P, Lampach D, Szodl A, Supper P, Bauer D, Beer A, Stift J, Timelthaler G, Oberhuber G, Podesser BK, Seif M, Zinober K, Rohr-Udilova N, Trauner M, Reiberger T, Schwabl P. Soluble guanylyl cyclase stimulation and phosphodiesterase-5 inhibition improve portal hypertension and reduce liver fibrosis in bile duct-ligated rats. United European Gastroenterol J. 2020 Dec;8(10):1174-1185. doi: 10.1177/2050640620944140. Epub 2020 Sep 2.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32878579/

Burigotto M, Mattivi A, Migliorati D, Magnani G, Valentini C, Roccuzzo M, Offterdinger M, Pizzato M, Schmidt A, Villunger A, Maffini S, Fava LL. Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26. EMBO J. 2021 Feb 15;40(4):e104844. doi: 10.15252/embj.2020104844. Epub 2020 Dec 22.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33350486/

Cinquina V, Calvigioni D, Farlik M, Halbritter F, Fife-Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, Mackie K, McBain CJ, Bock C, Keimpema E, Harkany T. Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy. Mol Psychiatry. 2020 Jan;25(1):22-36. doi: 10.1038/s41380-019-0580-4. Epub 2019 Nov 18.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31735910

Connolly P, Garcia-Carpio I, Villunger A. Cell-Cycle Cross Talk with Caspases and Their Substrates. Cold Spring Harb Perspect Biol. 2020 Jun 1;12(6):a036475. doi: 10.1101/cshperspect.a036475.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31727679/

Costa D, Simbrunner B, Jachs M, Hartl L, Bauer D, Paternostro R, Schwabl P, Scheiner B, Stättermayer AF, Pinter M, Trauner M, Mandorfer M, Reiberger T. Systemic inflammation increases across distinct stages of advanced chronic liver disease and correlates with decompensation and mortality. J Hepatol. 2021 Apr;74(4):819-828. doi: 10.1016/j.jhep.2020.10.004. Epub 2020 Oct 16.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33075344/

Delacher M, Imbusch CD, Hotz-Wagenblatt A, Mallm JP, Bauer K, Simon M, Riegel D, Rendeiro AF, Bittner S, Sanderink L, Pant A, Schmidleithner L, Braband KL, Echtenachter B, Fischer A, Giunchiglia V, Hoffmann P, Edinger M, Bock C, Rehli M, Brors B, Schmidl C, Feuerer M. Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF. Immunity. 2020 Feb 18;52(2):295-312.e11. doi: 10.1016/j.immuni.2019.12.002. Epub 2020 Jan 7.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31924477

Dobon B, Ter Horst R, Laayouni H, Mondal M, Bianco E, Comas D, Ioana M, Bosch E, Bertranpetit J, Netea MG. The shaping of immunological responses through natural selection after the Roma Diaspora. Sci Rep. 2020 Sep 30;10(1):16134. doi: 10.1038/s41598-020-73182-1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32999407/

Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms. Gut. 2020 Sep 9:gutjnl-2019-319227. doi: 10.1136/gutjnl-2019-319227. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32907830/

Fagone P, Ciurleo R, Lombardo SD, Iacobello C, Palermo CI, Shoenfeld Y, Bendtzen K, Bramanti P, Nicoletti F. Transcriptional landscape of SARS-CoV-2 infection dismantles pathogenic pathways activated by the virus, proposes unique sex-specific differences and predicts tailored therapeutic strategies. Autoimmun Rev. 2020 Jul;19(7):102571. doi: 10.1016/j.autrev.2020.102571. Epub 2020 May 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32376402/

Fellinger P, Wolf P, Pfleger L, Krumpolec P, Krssak M, Klavins K, Wolfsberger S, Micko A, Carey P, Gürtl B, Vila G, Raber W, Fürnsinn C, Scherer T, Trattnig S, Kautzky-Willer A, Krebs M, Winhofer Y. Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly. JCI Insight. 2020 Mar 12;5(5):e134638. doi: 10.1172/jci.insight.134638.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32106111

Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Grosche S, Rüschendorf F, Granell R, Brumpton BM, Fritsche LG, Bhatta L, Gabrielsen ME, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Emami NC, Cavazos TB, Witte JS, Szwajda A; 23andMe Research Team; collaborators of the SHARE study, Hinds DA, Hübner N, Weidinger S, Magnusson PK, Jorgenson E, Karlsson R, Paternoster L, Boomsma DI, Almqvist C, Lee YA, Koppelman GH. Age-of-onset information helps identify 76 genetic variants associated with allergic disease. PLoS Genet. 2020 Jun 30;16(6):e1008725. doi: 10.1371/journal.pgen.1008725.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32603359/

Fortelny N, Bock C. Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data. Genome Biol. 2020 Aug 3;21(1):190. doi: 10.1186/s13059-020-02100-5.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32746932/

Gasteiger LM, Robinson PN, Pazmandi J, Boztug K, Seppänen MRJ, Seidel MG; Registry Working Party of the European Society for Immunodeficiencies (ESID). Supplementation of the ESID registry working definitions for the clinical diagnosis of inborn errors of immunity with encoded human phenotype ontology (HPO) terms. J Allergy Clin Immunol Pract. 2020 May;8(5):1778. doi: 10.1016/j.jaip.2020.02.019.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32389282

Gaviraghi M, Rabellino A, Andolfo A, Brand M, Brombin C, Bagnato P, De Feudis G, Raimondi A, Locatelli A, Tosoni D, Mazza D, Gianni L, Tonon G, Yarden Y, Tacchetti C, Daniele T. Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor Thr(701) phosphorylation. Sci Rep. 2020 Oct 9;10(1):16906. doi: 10.1038/s41598-020-73835-1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33037285/

Geissler K, Gisslinger B, Jäger E, Jäger R, Schiefer AI, Bogner E, Fuchs E, Schischlik F, Alpar D, Simonitsch-Klupp I, Kralovics R, Gisslinger H. Myelomonocytic Skewing In Vitro Discriminates Subgroups of Patients with Myelofibrosis with A Different Phenotype, A Different Mutational Profile and Different Prognosis. Cancers (Basel). 2020 Aug 14;12(8):2291. doi: 10.3390/cancers12082291.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32824053/

Ghosh S, Köstel Bal S, Edwards ESJ, Pillay B, Jiménez Heredia R, Erol Cipe F, Rao G, Salzer E, Zoghi S, Abolhassani H, Momen T, Gostick E, Price DA, Zhang Y, Oler AJ, Gonzaga-Jauregui C, Erman B, Metin A, Ilhan I, Haskologlu S, Islamoglu C, Baskin K, Ceylaner S, Yilmaz E, Unal E, Karakukcu M, Berghuis D, Cole T, Gupta AK, Hauck F, Kogler H, Hoepelman AIM, Baris S, Karakoc-Aydiner E, Ozen A, Kager L, Holzinger D, Paulussen M, Krüger R, Meisel R, Oommen PT, Morris E, Neven B, Worth A, van Montfrans J, Fraaij PLA, Choo S, Dogu F, Davies EG, Burns S, Dückers G, Becker RP, von Bernuth H, Latour S, Faraci M, Gattorno M, Su HC, Pan-Hammarström Q, Hammarström L, Lenardo MJ, Ma CS, Niehues T, Aghamohammadi A, Rezaei N, Ikinciogullari A, Tangye SG, Lankester AC, Boztug K. Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency. Blood. 2020 Dec 3;136(23):2638-2655. doi: 10.1182/blood.2020006738.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32603431/

Girardi E, Agrimi G, Goldmann U, Fiume G, Lindinger S, Sedlyarov V, Srndic I, Gürtl B, Agerer B, Kartnig F, Scarcia P, Di Noia MA, Liñeiro E, Rebsamen M, Wiedmer T, Bergthaler A, Palmieri L, Superti-Furga G. Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import. Nat Commun. 2020 Dec 1;11(1):6145. doi: 10.1038/s41467-020-19871-x.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33262325/

Girardi E, Superti-Furga G. Caught in the genetic network: a novel regulator of lipid metabolism. Nat Metab. 2020 Jun;2(6):483-484. doi: 10.1038/s42255-020-0218-5.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32694730/

Gisslinger H, Klade C, Georgiev P, Krochmalczyk D, Gercheva-Kyuchukova L, Egyed M, Rossiev V, Dulicek P, Illes A, Pylypenko H, Sivcheva L, Mayer J, Yablokova V, Krejcy K, Grohmann-Izay B, Hasselbalch HC, Kralovics R, Kiladjian JJ; PROUD-PV Study Group. Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non- inferiority, phase 3 trial and its extension study. Lancet Haematol. 2020 Mar;7(3):e196-e208. doi: 10.1016/S2352-3026(19)30236-4. Epub 2020 Jan 31. Erratum in: Lancet Haematol. 2020 Feb 25.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32014125

Gisslinger H, Klade C, Georgiev P, Krochmalczyk D, Gercheva-Kyuchukova L, Egyed M, Rossiev V, Dulicek P, Illes A, Pylypenko H, Sivcheva L, Mayer J, Yablokova V, Krejcy K, Hasselbalch HC, Kralovics R, Kiladjian JJ. Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age Groups. Hemasphere. 2020 Oct 20;4(6):e485. doi: 10.1097/HS9.0000000000000485.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33134869/

Göschl L, Winkler S, Dmytrus J, Heredia RJ, Lagler H, Ramharter M, Scheinecker C, Bonelli M, Schmetterer K, Pickl WF, Grabmeier-Pfistershammer K, Hershfield MS, Boztug K, Förster-Waldl E, Gualdoni GA. Unreported Missense Mutation in the Dimerization Domain of ADA2 Leads to ADA2 Deficiency Associated with Severe Oral Ulcers and Neutropenia in a Female Somalian Patient-Addendum to the Genotype-Phenotype Puzzle. J Clin Immunol. 2020 Jan;40(1):223-226. doi: 10.1007/s10875-019-00700-w. Epub 2019 Nov 4.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31686313

Hagelkruys A, Wirnsberger G, Stadlmann J, Wöhner M, Horrer M, Vilagos B, Jonsson G, Kogler M, Tortola L, Novatchkova M, Bönelt P, Hoffmann D, Koglgruber R, Steffen U, Schett G, Busslinger M, Bergthaler A, Klein C, Penninger JM. A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans. J Exp Med. 2021 Jan 4;218(1):e20200559. doi: 10.1084/jem.20200559.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32930709/

Hainberger D, Stolz V, Zhu C, Schuster M, Müller L, Hamminger P, Rica R, Waltenberger D, Alteneder M, Krausgruber T, Hladik A, Knapp S, Bock C, Trauner M, Farrar MA, Ellmeier W. NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells. Front Immunol. 2020 Apr 3;11:579. doi: 10.3389/fimmu.2020.00579.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32318068

Hanitsch L, Baumann U, Boztug K, Burkhard-Meier U, Fasshauer M, Habermehl P, Hauck F, Klock G, Liese J, Meyer O, Müller R, Pachlopnik-Schmid J, Pfeiffer- Kascha D, Warnatz K, Wehr C, Wittke K, Niehues T, von Bernuth H. Treatment and management of primary antibody deficiency: German interdisciplinary evidence-based consensus guideline. Eur J Immunol. 2020 Oct;50(10):1432-1446. doi: 10.1002/eji.202048713. Epub 2020 Sep 9.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32845010/

Hanzl A, Winter GE. Targeted protein degradation: current and future challenges. Curr Opin Chem Biol. 2020 Jun;56:35-41. doi: 10.1016/j.cbpa.2019.11.012. Epub 2020 Jan 2. PMID: 31901786.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31901786/

Haschka MD, Karbon G, Soratroi C, O'Neill KL, Luo X, Villunger A. MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. Cell Death Differ. 2020 Aug;27(8):2297-2312. doi: 10.1038/s41418-020-0503-6. Epub 2020 Feb 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32015503/

Heinz LX, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César- Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn JW, Scorzoni S, Pizzagalli MD, Bensimon A, Müller AC, King FJ, Li J, Girardi E, Mbow ML, Whitehurst CE, Rebsamen M, Superti-Furga G. TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32433612

Hendrikx T, Binder CJ. Oxidation-Specific Epitopes in Non-Alcoholic Fatty Liver Disease. Front Endocrinol (Lausanne). 2020 Dec 9;11:607011. doi: 10.3389/fendo.2020.607011.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33362721/

Hofheinz K, Seibert F, Ackermann JA, Dietel B, Tauchi M, Oszvar-Kozma M, Kühn H, Schett G, Binder CJ, Krönke G. Formation of atherosclerotic lesions is independent of eosinophils in male mice. Atherosclerosis. 2020 Oct;311:67-72. doi: 10.1016/j.atherosclerosis.2020.08.030. Epub 2020 Sep 8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32947200/

Hubmann R, Schnabl S, Araghi M, Schmidl C, Rendeiro AF, Hilgarth M, Demirtas D, Ali F, Staber PB, Valent P, Zielinski C, Jäger U, Shehata M. Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL. Cells. 2020 Jun 18;9(6):1484. doi: 10.3390/cells9061484.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32570839/

Hutter K, Lohmüller M, Jukic A, Eichin F, Avci S, Labi V, Szabo TG, Hoser SM, Hüttenhofer A, Villunger A, Herzog S. SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts. Mol Cell. 2020 Jun 4;78(5):876-889.e6. doi: 10.1016/j.molcel.2020.05.011.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32502422/

Hutter K, Rülicke T, Drach M, Andersen L, Villunger A, Herzog S. Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis. FEBS J. 2021 Mar;288(5):1533-1545. doi: 10.1111/febs.15493. Epub 2020 Aug 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32705746/

Ilott NE, Bollrath J, Danne C, Schiering C, Shale M, Adelmann K, Krausgruber T, Heger A, Sims D, Powrie F. Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling. ISME J. 2020 Mar;14(3):879. doi: 10.1038/s41396-019-0539-0. Erratum for: ISME J. 2016 Oct;10(10):2389-404.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31748709

Imhof S, Kokotović T, Nagy V. PRDM12: New Opportunity in Pain Research. Trends Mol Med. 2020 Oct;26(10):895-897. doi: 10.1016/j.molmed.2020.07.007. Epub 2020 Aug 20.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32828702/

Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler A, Gray NS, Bradner JE, Bock C, Hnisz D, Cramer P, Winter GE. Selective Mediator dependence of cell-type-specifying transcription. Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32483291/

Jaeger MG, Winter GE. Expanding the Degradable Proteome: Designing PROTACs by the Book. Cell Chem Biol. 2020 Jan 16;27(1):14-16. doi: 10.1016/j.chembiol.2019.12.009.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31951815

Jia R, Kralovics R. Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions. Int J Hematol. 2020 Feb;111(2):182-191. doi: 10.1007/s12185-019-02778-9. Epub 2019 Nov 18.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31741139

Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, Plomp R, Mulder A, Ferrone S, Claas FHJ, Heemskerk MHM, Griffioen M, Halenius A, Overkleeft H, Huppa JB, Wuhrer M, Brummelkamp TR, Neefjes J, Spaapen RM. The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses. Immunity. 2021 Jan 12;54(1):132-150.e9. doi: 10.1016/j.immuni.2020.11.003. Epub 2020 Dec 2. Erratum in: Immunity. 2021 Feb 9;54(2):387.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33271119/

Jühling F, Hamdane N, Crouchet E, Li S, El Saghire H, Mukherji A, Fujiwara N, Oudot MA, Thumann C, Saviano A, Roca Suarez AA, Goto K, Masia R, Sojoodi M, Arora G, Aikata H, Ono A, Tabrizian P, Schwartz M, Polyak SJ, Davidson I, Schmidl C, Bock C, Schuster C, Chayama K, Pessaux P, Tanabe KK, Hoshida Y, Zeisel MB, Duong FH, Fuchs BC, Baumert TF. Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma. Gut. 2020 Mar 26:gutjnl-2019-318918. doi: 10.1136/gutjnl-2019-318918. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32217639

Keszei Z, Vendrell XM, Soultsioti M, Molina PR, Wirth L, Weiss H, Alexandridi M, Aloise C, Susma B, Guy C, Loverre A, Martinez SM, Mazej J, Spahn A, Sularea M, Hiscott J, Hoogen BVD. 100 days of solitude: The spring of COVID-19 through the eyes of 15 young virologists of the INITIATE program. Virus Res. 2020 Oct 2;287:198093. doi: 10.1016/j.virusres.2020.198093. Epub 2020 Jul 28.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32730780/

Keuenhof K, Heimel P, Zopf LM, Raigel M, Turyanskaya A, Kavirayani A, Reier S, Glösmann M, Schöfer C, Kralovics R, Streli C, Weninger WJ, Geyer SH, Slezak P, Macfelda K, Jäger R, Wanek T, Walter A. Multimodality imaging beyond CLEM: Showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions. Methods Cell Biol. 2021;162:389-415. doi: 10.1016/bs.mcb.2020.10.002. Epub 2020 Dec 2.
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Khalili N, Mohammadzadeh I, Khalili N, Heredia RJ, Zoghi S, Boztug K, Rezaei N. BCGitis as the primary manifestation of chronic granulomatous disease. IDCases. 2020 Dec 29;23:e01038. doi: 10.1016/j.idcr.2020.e01038.
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Khou S, Popa A, Luci C, Bihl F, Meghraoui-Kheddar A, Bourdely P, Salavagione E, Cosson E, Rubod A, Cazareth J, Barbry P, Mari B, Rezzonico R, Anjuère F, Braud VM. Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development. Cancers (Basel). 2020 Jul 10;12(7):1860. doi: 10.3390/cancers12071860.
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Korchynska S, Krassnitzer M, Malenczyk K, Prasad RB, Tretiakov EO, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger SN, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak DD, Romanov RA, Pifl C, Groop L, Hökfelt TG, Harkany T. Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants. EMBO J. 2020 Jan 2;39(1):e100882. doi: 10.15252/embj.2018100882. Epub 2019 Nov 21.
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Krall N, Superti-Furga G, Vladimer GI. Patient-derived model systems and the development of next-generation anticancer therapeutics. Curr Opin Chem Biol. 2020 Jun;56:72-78. doi: 10.1016/j.cbpa.2020.01.002. Epub 2020 Feb 18.
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Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidl C, Rendeiro AF, Bergthaler A, Bock C. Structural cells are key regulators of organ-specific immune responses. Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1.
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Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidl C, Rendeiro AF, Bergthaler A, Bock C. Structural cells are key regulators of organ-specific immune responses. Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1.
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Kreidl P, Schmid D, Maritschnik S, Richter L, Borena W, Genger JW, Popa A, Penz T, Bock C, Bergthaler A, Allerberger F. Emergence of coronavirus disease 2019 (COVID-19) in Austria. Wien Klin Wochenschr. 2020 Nov;132(21-22):645-652. doi: 10.1007/s00508-020-01723-9. Epub 2020 Aug 20.
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Kremslehner C, Miller A, Nica R, Nagelreiter IM, Narzt MS, Golabi B, Vorstandlechner V, Mildner M, Lachner J, Tschachler E, Ferrara F, Klavins K, Schosserer M, Grillari J, Haschemi A, Gruber F. Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents - Implications for oxidative UV damage. Redox Biol. 2020 Oct;37:101583. doi: 10.1016/j.redox.2020.101583. Epub 2020 Jul 19.
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Kretzmer H, Biran A, Purroy N, Lemvigh C, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes S, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps 9: Wöran K, Semmler G, Jachs M, Simbrunner B, Maria Bauer DJ, Binter T, Pomej K, Stättermayer AF, Schwabl P, Bucsics T, Paternostro R, Lampichler K, Pinter M, Trauner M, Mandorfer M, Stift J, Reiberger T, Scheiner B. Clinical Course of Porto-Sinusoidal Vascular Disease Is Distinct From Idiopathic Noncirrhotic Portal Hypertension. Clin Gastroenterol Hepatol. 2020 Dec 3:S1542-3565(20)31629-3. doi: 10.1016/j.cgh.2020.11.039. Epub ahead of print.
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Krüger R, Martin E, Dmytrus J, Feiterna-Sperling C, Meisel C, Unterwalder N, Kölsch U, Wahn V, Hofmann J, Korn P, Latour S, Boztug K, von Bernuth H. CD70 Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman. Front Immunol. 2020 Aug 4;11:1593. doi: 10.3389/fimmu.2020.01593.
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Köstel Bal S, Pazmandi J, Boztug K, Özen S. Rheumatological manifestations in inborn errors of immunity. Pediatr Res. 2020 Jan;87(2):293-299. doi: 10.1038/s41390-019-0600-8. Epub 2019 Oct 3.
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Lang C, Jaksch P, Hoda MA, Lang G, Staudinger T, Tschernko E, Zapletal B, Geleff S, Prosch H, Gawish R, Knapp S, Robak O, Thalhammer F, Indra A, Koestenberger M, Strassl R, Klikovits T, Ali K, Fischer G, Klepetko W, Hoetzenecker K, Schellongowski P. Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient. Lancet Respir Med. 2020 Oct;8(10):1057-1060. doi: 10.1016/S2213-2600(20)30361-1. Epub 2020 Aug 25.
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Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, Wong M, O'Sullivan M, Boztug K, Meyts I, Uzel G, Notarangelo LD, Brink R, Goodnow CC, Tangye SG, Deenick EK. Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production. J Exp Med. 2020 Feb 3;217(2):e20191336. doi: 10.1084/jem.20191336.
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Laukoter S, Pauler FM, Beattie R, Amberg N, Hansen AH, Streicher C, Penz T, Bock C, Hippenmeyer S. Cell-Type Specificity of Genomic Imprinting in Cerebral Cortex. Neuron. 2020 Sep 23;107(6):1160-1179.e9. doi: 10.1016/j.neuron.2020.06.031. Epub 2020 Jul 23.
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Lercher A, Baazim H, Bergthaler A. Systemic Immunometabolism: Challenges and Opportunities. Immunity. 2020 Sep 15;53(3):496-509. doi: 10.1016/j.immuni.2020.08.012.
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Lercher A, Popa AM, Viczenczova C, Kosack L, Klavins K, Agerer B, Opitz CA, Lanz TV, Platten M, Bergthaler A. Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis. PLoS Pathog. 2020 Oct 12;16(10):e1008973. doi: 10.1371/journal.ppat.1008973.
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Liu GJ, Jaritz M, Wöhner M, Agerer B, Bergthaler A, Malin SG, Busslinger M. Repression of the B cell identity factor Pax5 is not required for plasma cell development. J Exp Med. 2020 Nov 2;217(11):e20200147. doi: 10.1084/jem.20200147.
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Lomakin AJ, Cattin CJ, Cuvelier D, Alraies Z, Molina M, Nader GPF, Srivastava N, Sáez PJ, Garcia-Arcos JM, Zhitnyak IY, Bhargava A, Driscoll MK, Welf ES, Fiolka R, Petrie RJ, De Silva NS, González-Granado JM, Manel N, Lennon- Duménil AM, Müller DJ, Piel M. The nucleus acts as a ruler tailoring cell responses to spatial constraints. Science. 2020 Oct 16;370(6514):eaba2894. doi: 10.1126/science.aba2894.
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Lombardo SD, Bramanti A, Ciurleo R, Basile MS, Pennisi M, Bella R, Mangano K, Bramanti P, Nicoletti F, Fagone P. Profiling of inhibitory immune checkpoints in glioblastoma: Potential pathogenetic players. Oncol Lett. 2020 Dec;20(6):332. doi: 10.3892/ol.2020.12195. Epub 2020 Oct 7.
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Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32111832

Lorenzini T, Fliegauf M, Klammer N, Frede N, Proietti M, Bulashevska A, Camacho-Ordonez N, Varjosalo M, Kinnunen M, de Vries E, van der Meer JWM, Ameratunga R, Roifman CM, Schejter YD, Kobbe R, Hautala T, Atschekzei F, Schmidt RE, Schröder C, Stepensky P, Shadur B, Pedroza LA, van der Flier M, Martínez-Gallo M, Gonzalez-Granado LI, Allende LM, Shcherbina A, Kuzmenko N, Zakharova V, Neves JF, Svec P, Fischer U, Ip W, Bartsch O, Barış S, Klein C, Geha R, Chou J, Alosaimi M, Weintraub L, Boztug K, Hirschmugl T, Dos Santos Vilela MM, Holzinger D, Seidl M, Lougaris V, Plebani A, Alsina L, Piquer-Gibert M, Deyà-Martínez A, Slade CA, Aghamohammadi A, Abolhassani H, Hammarström L, Kuismin O, Helminen M, Allen HL, Thaventhiran JE, Freeman AF, Cook M, Bakhtiar S, Christiansen M, Cunningham-Rundles C, Patel NC, Rae W, Niehues T, Brauer N, Syrjänen J, Seppänen MRJ, Burns SO, Tuijnenburg P, Kuijpers TW, Warnatz K, Grimbacher B; NIHR BioResource. Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. J Allergy Clin Immunol. 2020 Oct;146(4):901-911. doi: 10.1016/j.jaci.2019.11.051. Epub 2020 Apr 9.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32278790/

Maurer B, Nivarthi H, Wingelhofer B, Pham HTT, Schlederer M, Suske T, Grausenburger R, Schiefer AI, Prchal-Murphy M, Chen D, Winkler S, Merkel O, Kornauth C, Hofbauer M, Hochgatterer B, Hoermann G, Hoelbl-Kovacic A, Prochazkova J, Lobello C, Cumaraswamy AA, Latzka J, Kitzwögerer M, Chott A, Janikova A, Pospíšilova Š, Loizou JI, Kubicek S, Valent P, Kolbe T, Grebien F, Kenner L, Gunning PT, Kralovics R, Herling M, Müller M, Rülicke T, Sexl V, Moriggl R. High activation of STAT5A drives peripheral T-cell lymphoma and leukemia. Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31123029

Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, Müller AC, Zuber J, Geyer M, Thomä NH, Kubicek S, Winter GE. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. Erratum in: Nat Chem Biol. 2021 Mar;17(3):361.
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Meixner E, Goldmann U, Sedlyarov V, Scorzoni S, Rebsamen M, Girardi E, Superti-Furga G. A substrate-based ontology for human solute carriers. Mol Syst Biol. 2020 Jul;16(7):e9652. doi: 10.15252/msb.20209652.
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Moretton A, Loizou JI. Interplay between Cellular Metabolism and the DNA Damage Response in Cancer. Cancers (Basel). 2020 Jul 25;12(8):2051. doi: 10.3390/cancers12082051.
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Moura HM, Unterlass MM. Biogenic Metal Oxides. Biomimetics (Basel). 2020 Jun 23;5(2):29. doi: 10.3390/biomimetics5020029.
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Mussbacher M, Salzmann M, Haigl B, Basílio J, Hochreiter B, Gleitsmann V, Moser B, Hoesel B, Suur BE, Puhm F, Ungerböck C, Kuttke M, Forteza MJ, Binder CJ, Ketelhuth DFJ, Assinger A, Schmid JA. Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis. Atherosclerosis. 2020 Aug;307:21-31. doi: 10.1016/j.atherosclerosis.2020.06.005. Epub 2020 Jul 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32711212/

Nenning KH, Furtner J, Kiesel B, Schwartz E, Roetzer T, Fortelny N, Bock C, Grisold A, Marko M, Leutmezer F, Liu H, Golland P, Stoecklein S, Hainfellner JA, Kasprian G, Prayer D, Marosi C, Widhalm G, Woehrer A, Langs G. Distributed changes of the functional connectome in patients with glioblastoma. Sci Rep. 2020 Oct 27;10(1):18312. doi: 10.1038/s41598-020-74726-1.
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Paolino M, Koglgruber R, Cronin SJF, Uribesalgo I, Rauscher E, Harreiter J, Schuster M, Bancher-Todesca D, Pranjic B, Novatchkova M, Fededa JP, White AJ, Sigl V, Dekan S, Penz T, Bock C, Kenner L, Holländer GA, Anderson G, Kautzky-Willer A, Penninger JM. RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy. Nature. 2021 Jan;589(7842):442-447. doi: 10.1038/s41586-020-03071-0. Epub 2020 Dec 23.
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Paternostro R, Pfeiffenberger J, Ferenci P, Stättermayer AF, Stauber RE, Wrba F, Longerich T, Lackner K, Trauner M, Ferlitsch A, Reiberger T, Weiss KH. Non-invasive diagnosis of cirrhosis and long-term disease monitoring by transient elastography in patients with Wilson disease. Liver Int. 2020 Apr;40(4):894-904. doi: 10.1111/liv.14368. Epub 2020 Jan 22.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31898387

Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ. Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ. 2020 Sep;27(9):2620-2634. doi: 10.1038/s41418-020-0527-y. Epub 2020 Mar 19.
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Pizzagalli MD, Bensimon A, Superti-Furga G. A guide to plasma membrane solute carrier proteins. FEBS J. 2021 May;288(9):2784-2835. doi: 10.1111/febs.15531. Epub 2020 Sep 18.
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Popa A, Genger JW, Nicholson MD, Penz T, Schmid D, Aberle SW, Agerer B, Lercher A, Endler L, Colaço H, Smyth M, Schuster M, Grau ML, Martínez-Jiménez F, Pich O, Borena W, Pawelka E, Keszei Z, Senekowitsch M, Laine J, Aberle JH, Redlberger-Fritz M, Karolyi M, Zoufaly A, Maritschnik S, Borkovec M, Hufnagl P, Nairz M, Weiss G, Wolfinger MT, von Laer D, Superti-Furga G, Lopez-Bigas N, Puchhammer-Stöckl E, Allerberger F, Michor F, Bock C, Bergthaler A. Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2. Sci Transl Med. 2020 Dec 9;12(573):eabe2555. doi: 10.1126/scitranslmed.abe2555. Epub 2020 Nov 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33229462/

Porte V, Di Mauro G, Schupp M, Kaiser D, Maulide N. Chemoselective Alpha-Deuteration of Amides via Retro-ene Reaction. Chemistry. 2020 Dec 1;26(67):15509-15512. doi: 10.1002/chem.202004103. Epub 2020 Nov 17.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33035360/

Preglej T, Hamminger P, Luu M, Bulat T, Andersen L, Göschl L, Stolz V, Rica R, Sandner L, Waltenberger D, Tschismarov R, Faux T, Boenke T, Laiho A, Elo LL, Sakaguchi S, Steiner G, Decker T, Bohle B, Visekruna A, Bock C, Strobl B, Seiser C, Boucheron N, Ellmeier W. Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation. JCI Insight. 2020 Feb 27;5(4):e133393. doi: 10.1172/jci.insight.133393.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32102981

Quijada-Álamo M, Hernández-Sánchez M, Alonso-Pérez V, Rodríguez-Vicente AE, García-Tuñón I, Martín-Izquierdo M, Hernández-Sánchez JM, Herrero AB, Bastida JM, San Segundo L, Gruber M, García JL, Yin S, Ten Hacken E, Benito R, Ordóñez JL, Wu CJ, Hernández-Rivas JM. CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition. Leukemia. 2020 Jan 23. doi: 10.1038/s41375-020-0714-3. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31974435

Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T; LifeTime Community Working Groups. LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 2020 Nov;587(7834):377-386. doi: 10.1038/s41586-020-2715-9. Epub 2020 Sep 7. Erratum in: Nature. 2021 Apr;592(7852):E8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32894860/

Redl E, Sheibani-Tezerji R, Cardona CJ, Hamminger P, Timelthaler G, Hassler MR, Zrimšek M, Lagger S, Dillinger T, Hofbauer L, Draganić K, Tiefenbacher A, Kothmayer M, Dietz CH, Ramsahoye BH, Kenner L, Bock C, Seiser C, Ellmeier W, Schweikert G, Egger G. Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis. Life Sci Alliance. 2020 Dec 11;4(2):e202000794. doi: 10.26508/lsa.202000794.
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Reicher A, Koren A, Kubicek S. Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time. Genome Res. 2020 Dec;30(12):1846-1855. doi: 10.1101/gr.261503.120. Epub 2020 Nov 17.
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Rizzotto D, Villunger A. P53 clears aneuploid cells by entosis. Cell Death Differ. 2021 Feb;28(2):818-820. doi: 10.1038/s41418-020-00659-x. Epub 2020 Nov 4.
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Rojahn TB, Vorstandlechner V, Krausgruber T, Bauer WM, Alkon N, Bangert C, Thaler FM, Sadeghyar F, Fortelny N, Gernedl V, Rindler K, Elbe-Bürger A, Bock C, Mildner M, Brunner PM. Single-cell transcriptomics combined with interstitial fluid proteomics defines cell type-specific immune regulation in atopic dermatitis. J Allergy Clin Immunol. 2020 Nov;146(5):1056-1069. doi: 10.1016/j.jaci.2020.03.041. Epub 2020 Apr 25.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32344053/

Rojahn TB, Vorstandlechner V, Krausgruber T, Bauer WM, Alkon N, Bangert C, Thaler FM, Sadeghyar F, Fortelny N, Gernedl V, Rindler K, Elbe-Bürger A, Bock C, Mildner M, Brunner PM. Single-cell transcriptomics combined with interstitial fluid proteomics defines cell-type-specific immune regulation in atopic dermatitis. J Allergy Clin Immunol. 2020 Apr 25:S0091-6749(20)30556-X. doi: 10.1016/j.jaci.2020.03.041. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32344053

Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews WD, Parnavelas JG, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T. Molecular design of hypothalamus development. Nature. 2020 Jun;582(7811):246-252. doi: 10.1038/s41586-020-2266-0. Epub 2020 May 6.
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Rosser EC, Piper CJM, Matei DE, Blair PA, Rendeiro AF, Orford M, Alber DG, Krausgruber T, Catalan D, Klein N, Manson JJ, Drozdov I, Bock C, Wedderburn LR, Eaton S, Mauri C. Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells. Cell Metab. 2020 Apr 7;31(4):837-851.e10. doi: 10.1016/j.cmet.2020.03.003. Epub 2020 Mar 25.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32213346

Ruiz-Villalba A, Romero JP, Hernández SC, Vilas-Zornoza A, Fortelny N, Castro-Labrador L, San Martin-Uriz P, Lorenzo-Vivas E, García-Olloqui P, Palacio M, Gavira JJ, Bastarrika G, Janssens S, Wu M, Iglesias E, Abizanda G, de Morentin XM, Lasaga M, Planell N, Bock C, Alignani D, Medal G, Prudovsky I, Jin YR, Ryzhov S, Yin H, Pelacho B, Gomez-Cabrero D, Lindner V, Lara-Astiaso D, Prósper F. Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction. Circulation. 2020 Nov 10;142(19):1831-1847. doi: 10.1161/CIRCULATIONAHA.119.044557. Epub 2020 Sep 25.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32972203/

Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt M, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Sci Immunol. 2020 Jul 10;5(49):eabc3979. doi: 10.1126/sciimmunol.abc3979.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32646852/

Sarbanes SL, Blomen VA, Lam E, Heissel S, Luna JM, Brummelkamp TR, Falck-Pedersen E, Hoffmann HH, Rice CM. E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015794118. doi: 10.1073/pnas.2015794118. Epub 2020 Dec 21.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33443154/

Scherer M, Nebel A, Franke A, Walter J, Lengauer T, Bock C, Müller F, List M. Quantitative comparison of within-sample heterogeneity scores for DNA methylation data. Nucleic Acids Res. 2020 May 7;48(8):e46. doi: 10.1093/nar/gkaa120.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32103242

Schrempf A, Slyskova J, Loizou JI. Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy. Trends Cancer. 2021 Feb;7(2):98-111. doi: 10.1016/j.trecan.2020.09.007. Epub 2020 Oct 24.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33109489/

Schrottmaier WC , Salzmann M, Badrnya S, Mussbacher M, Kral-Pointner JB, Morava S, Pirabe A, Brunnthaler L, Yaiw KC, Heber UM, Pereyra D, Andersen JT, Bergthaler A, Söderberg-Nauclér C, Karlsson MCI, Assinger A, Forsell MNE. Platelets mediate serological memory to neutralize viruses in vitro and in vivo. Blood Adv. 2020 Aug 25;4(16):3971-3976. doi: 10.1182/bloodadvances.2020001786.  
Abstract: https://pubmed.ncbi.nlm.nih.gov/32841338/

Schwarz S, Rahimi N, Kifjak D, Muckenhuber M, Watzenböck M, Benazzo A, Jaksch P, Knapp S, Klepetko W, Hoetzenecker K; Vienna Lung Transplant Group. Comparison of donor scores in bilateral lung transplantation-A large single-center analysis. Am J Transplant. 2020 Nov 19. doi: 10.1111/ajt.16402. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33210825/

Simbrunner B, Marculescu R, Scheiner B, Schwabl P, Bucsics T, Stadlmann A, Bauer DJM, Paternostro R, Eigenbauer E, Pinter M, Stättermayer AF, Trauner M, Mandorfer M, Reiberger T. Non-invasive detection of portal hypertension by enhanced liver fibrosis score in patients with different aetiologies of advanced chronic liver disease. Liver Int. 2020 Jul;40(7):1713-1724. doi: 10.1111/liv.14498. Epub 2020 May 18.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32358998/

Simbrunner B, Semmler G, Stadlmann A, Scheiner B, Schwabl P, Paternostro R, Bucsics T, Bauer D, Eigenbauer E, Pinter M, Stättermayer AF, Quehenberger P, Marculescu R, Trauner M, Mandorfer M, Reiberger T. Vitamin A levels reflect disease severity and portal hypertension in patients with cirrhosis. Hepatol Int. 2020 Dec;14(6):1093-1103. doi: 10.1007/s12072-020-10112-3. Epub 2020 Dec 8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33289910/

Sladky VC, Knapp K, Soratroi C, Heppke J, Eichin F, Rocamora-Reverte L, Szabo TG, Bongiovanni L, Westendorp B, Moreno E, van Liere EA, Bakker B, Spierings DCJ, Wardenaar R, Pereyra D, Starlinger P, Schultze S, Trauner M, Stojakovic T, Scharnagl H, Fava LL, Foijer F, de Bruin A, Villunger A. E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration. Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31983631

Sladky VC, Knapp K, Szabo TG, Braun VZ, Bongiovanni L, van den Bos H, Spierings DC, Westendorp B, Curinha A, Stojakovic T, Scharnagl H, Timelthaler G, Tsuchia K, Pinter M, Semmler G, Foijer F, de Bruin A, Reiberger T, Rohr-Udilova N, Villunger A. PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis. EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33225610/

Sladky VC, Villunger A. Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation. Cell Death Differ. 2020 Jul;27(7):2037-2047. doi: 10.1038/s41418-020-0556-6. Epub 2020 May 15.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32415279/

Starkl P, Watzenboeck ML, Popov LM, Zahalka S, Hladik A, Lakovits K, Radhouani M, Haschemi A, Marichal T, Reber LL, Gaudenzio N, Sibilano R, Stulik L, Fontaine F, Mueller AC, Amieva MR, Galli SJ, Knapp S. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020 Oct 13;53(4):793-804.e9. doi: 10.1016/j.immuni.2020.08.002. Epub 2020 Sep 9. Erratum in: Immunity. 2020 Dec 15;53(6):1333.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32910906/

Stary V, Pandey RV, Strobl J, Kleissl L, Starlinger P, Pereyra D, Weninger W, Fischer GF, Bock C, Farlik M, Stary G. A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses. Sci Immunol. 2020 Oct 16;5(52):eaba6232. doi: 10.1126/sciimmunol.aba6232.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33067380/

Strobl J, Pandey RV, Krausgruber T, Bayer N, Kleissl L, Reininger B, Vieyra-Garcia P, Wolf P, Jentus MM, Mitterbauer M, Wohlfarth P, Rabitsch W, Stingl G, Bock C, Stary G. Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease. Sci Transl Med. 2020 Nov 18;12(570):eabb7028. doi: 10.1126/scitranslmed.abb7028.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33208504/

Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid- Refractory Graft-Versus-Host Disease. J Invest Dermatol. 2020 Apr 2:S0022-202X(20)31252-5. doi: 10.1016/j.jid.2020.02.029. Epub ahead of print.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32247860

Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G. Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid-Refractory Graft-Versus-Host Disease. J Invest Dermatol. 2020 Nov;140(11):2188-2198. doi: 10.1016/j.jid.2020.02.029. Epub 2020 Apr 2.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32247860/

Subtelna I, Kryshchyshyn-Dylevych A, Jia R, Lelyukh M, Ringler A, Kubicek S, Zagrijtschuk O, Kralovics R, Lesyk R. 5-Arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones with selective inhibitory activity against some leukemia cell lines. Arch Pharm (Weinheim). 2021 Apr;354(4):e2000342. doi: 10.1002/ardp.202000342. Epub 2020 Nov 25.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33241558/

Surface LE, Burrow DT, Li J, Park J, Kumar S, Lyu C, Song N, Yu Z, Rajagopal A, Bae Y, Lee BH, Mumm S, Gu CC, Baker JC, Mohseni M, Sum M, Huskey M, Duan S, Bijanki VN, Civitelli R, Gardner MJ, McAndrew CM, Ricci WM, Gurnett CA, Diemer K, Wan F, Costantino CL, Shannon KM, Raje N, Dodson TB, Haber DA, Carette JE, Varadarajan M, Brummelkamp TR, Birsoy K, Sabatini DM, Haller G, Peterson TR. ATRAID regulates the action of nitrogen-containing bisphosphonates on bone. Sci Transl Med. 2020 May 20;12(544):eaav9166. doi: 10.1126/scitranslmed.aav9166.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32434850

Swoboda A, Soukup R, Eckel O, Kinslechner K, Wingelhofer B, Schörghofer D, Sternberg C, Pham HTT, Vallianou M, Horvath J, Stoiber D, Kenner L, Larue L, Poli V, Beermann F, Yokota T, Kubicek S, Krausgruber T, Rendeiro AF, Bock C, Zenz R, Kovacic B, Aberger F, Hengstschläger M, Petzelbauer P, Mikula M, Moriggl R. STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway. Oncogene. 2021 Feb;40(6):1091-1105. doi: 10.1038/s41388-020-01584-6. Epub 2020 Dec 15.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33323974/

Szymczak S, Dose J, Torres GG, Heinsen FA, Venkatesh G, Datlinger P, Nygaard M, Mengel-From J, Flachsbart F, Klapper W, Christensen K, Lieb W, Schreiber S, Häsler R, Bock C, Franke A, Nebel A. DNA methylation QTL analysis identifies new regulators of human longevity. Hum Mol Genet. 2020 May 8;29(7):1154-1167. doi: 10.1093/hmg/ddaa033.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32160291

Süleyman M, Tan Ç, Uner A, İnkaya Ç, Aytaç S, Büyükaşık Y, Boztug K, Tezcan İ, Cagdas D. Adenosine Deaminase Type II Deficiency: Severe Chronic Neutropenia, Lymphoid Infiltration in Bone Marrow, and Inflammatory Features. Immunol Invest. 2020 Dec 2:1-9. doi: 10.1080/08820139.2020.1853153. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33705245/

Taublaender MJ, Mezzavilla S, Thiele S, Glöcklhofer F, Unterlass MM. Hydrothermal Generation of Conjugated Polymers Using the Example of Pyrrone Polymers and Polybenzimidazoles. Angew Chem Int Ed Engl. 2020 Aug 24;59(35):15050-15060. doi: 10.1002/anie.202000367. Epub 2020 May 11.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32255546/

Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc- Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Köstel Bal S, Baris S, Kilic SS, Karaca NE, Kutukculer N, Girschick H, Kolios A, Keles S, Uygun V, Stepensky P, Worth A, van Montfrans JM, Peters AMJ, Meyts I, Adeli M, Marzollo A, Padem N, Khojah AM, Chavoshzadeh Z, Avbelj Stefanija M, Bakhtiar S, Florkin B, Meeths M, Gamez L, Grimbacher B, Seppänen MRJ, Lankester A, Gennery AR, Seidel MG; Inborn Errors, Clinical, and Registry Working Parties of the European Society for Blood and Marrow Transplantation and the European Society for Immunodeficiencies. Long- term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score. J Allergy Clin Immunol. 2020 May;145(5):1452-1463. doi: 10.1016/j.jaci.2019.12.896. Epub 2019 Dec 27.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31887391

Thian M, Hoeger B, Kamnev A, Poyer F, Köstel Bal S, Caldera M, Jiménez-Heredia R, Huemer J, Pickl WF, Groß M, Ehl S, Lucas CL, Menche J, Hutter C, Attarbaschi A, Dupré L, Boztug K. Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation. Haematologica. 2020 Oct 1;105(10):e488. doi: 10.3324/haematol.2019.231399.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33054089/

Turelli P, Playfoot C, Grun D, Raclot C, Pontis J, Coudray A, Thorball C, Duc J, Pankevich EV, Deplancke B, Busskamp V, Trono D. Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons. Sci Adv. 2020 Aug 28;6(35):eaba3200. doi: 10.1126/sciadv.aba3200.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32923624/

Ubags NDJ, Alejandre Alcazar MA, Kallapur SG, Knapp S, Lanone S, Lloyd CM, Morty RE, Pattaroni C, Reynaert NL, Rottier RJ, Smits HH, de Steenhuijsen Piters WAA, Strickland DH, Collins JJP. Early origins of lung disease: towards an interdisciplinary approach. Eur Respir Rev. 2020 Oct 1;29(157):200191. doi: 10.1183/16000617.0191-2020.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33004528/

Ulz P, Perakis S, Zhou Q, Moser T, Belic J, Lazzeri I, Wölfler A, Zebisch A, Gerger A, Pristauz G, Petru E, White B, Roberts CES, John JS, Schimek MG, Geigl JB, Bauernhofer T, Sill H, Bock C, Heitzer E, Speicher MR. Publisher Correction: Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection. Nat Commun. 2020 Apr 20;11(1):1965. doi: 10.1038/s41467-020-15799-4. Erratum for: Nat Commun. 2019 Oct 11;10(1):4666.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32313081

Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32023468/

Wilson JL, Nägele T, Linke M, Demel F, Fritsch SD, Mayr HK, Cai Z, Katholnig K, Sun X, Fragner L, Miller A, Haschemi A, Popa A, Bergthaler A, Hengstschläger M, Weichhart T, Weckwerth W. Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation. Cell Rep. 2020 Feb 4;30(5):1542-1552.e7. doi: 10.1016/j.celrep.2020.01.011.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32023468

Wuerth JD, Habjan M, Kainulainen M, Berisha B, Bertheloot D, Superti-Furga G, Pichlmair A, Weber F. eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. mBio. 2020 Jul 14;11(4):e00976-20. doi: 10.1128/mBio.00976-20.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32665273/

Wöran K, Semmler G, Jachs M, Simbrunner B, Maria Bauer DJ, Binter T, Pomej K, Stättermayer AF, Schwabl P, Bucsics T, Paternostro R, Lampichler K, Pinter M, Trauner M, Mandorfer M, Stift J, Reiberger T, Scheiner B. Clinical Course of Porto-Sinusoidal Vascular Disease Is Distinct From Idiopathic Noncirrhotic Portal Hypertension. Clin Gastroenterol Hepatol. 2020 Dec 3:S1542-3565(20)31629-3. doi: 10.1016/j.cgh.2020.11.039. Epub ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33279774/

Yu YR, Imrichova H, Wang H, Chao T, Xiao Z, Gao M, Rincon-Restrepo M, Franco F, Genolet R, Cheng WC, Jandus C, Coukos G, Jiang YF, Locasale JW, Zippelius A, Liu PS, Tang L, Bock C, Vannini N, Ho PC. Disturbed mitochondrial dynamics in CD8(+) TILs reinforce T cell exhaustion. Nat Immunol. 2020 Dec;21(12):1540-1551. doi: 10.1038/s41590-020-0793-3. Epub 2020 Oct 5.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33020660/

Yucel E, Karakus IS, Krolo A, Kiykim A, Heredia RJ, Tamay Z, Cipe FE, Karakoc-Aydiner E, Ozen A, Karaman S, Boztug K, Baris S. Novel Frameshift Autosomal Recessive Loss-of-Function Mutation in SMARCD2 Encoding a Chromatin Remodeling Factor Mediates Granulopoiesis. J Clin Immunol. 2021 Jan;41(1):59-65. doi: 10.1007/s10875-020-00878-4. Epub 2020 Oct 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33025377/

Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM. Human recombinant soluble ACE2 in severe COVID-19. Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Erratum in: Lancet Respir Med. 2020 Nov;8(11):e78.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33131609/

de Bree LCJ, Mourits VP, Koeken VA, Moorlag SJ, Janssen R, Folkman L, Barreca D, Krausgruber T, Fife-Gernedl V, Novakovic B, Arts RJ, Dijkstra H, Lemmers H, Bock C, Joosten LA, van Crevel R, Benn CS, Netea MG. Circadian rhythm influences induction of trained immunity by BCG vaccination. J Clin Invest. 2020 Oct 1;130(10):5603-5617. doi: 10.1172/JCI133934.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32692732/

van den Hoogen B, Santoni A, Sciumé G, Bowie A, O'Farrelly C, O'Neill L, Anthonsen M, Pardali K, Young S, Bergthaler A, Manel N, Zahn R, Kikkert M, Snijder E, van Kuppeveld F, Fouchier R, Hiscott J. Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska- Curie innovative training network. Virus Res. 2020 Oct 2;287:198094. doi: 10.1016/j.virusres.2020.198094. Epub 2020 Jul 28.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32730781/

van den Hoogen B, Santoni  A, Sciumé G, Bowie A, O'Farrelly C, O'Neill L, Anthonsen M, Pardali K, Young S, Bergthaler A, Manel N, Zahn R, Kikkert M, Snijder E, van Kuppeveld F, Fouchier R, Hiscott J. Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network. Virus Res. 2020 Oct 2;287:198094. doi: 10.1016/j.virusres.2020.198094. Epub 2020 Jul 28.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32730781/

Çipe FE, Aydoğmuş Ç, Baskın K, Keskindemirci G, Garncarz W, Boztuğ K. A rare case of syndromic severe congenital neutropenia: JAGN1 mutation. Turk J Pediatr. 2020;62(2):326-331. doi: 10.24953/turkjped.2020.02.022.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/32419428