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Year
Paper
2011
Barlow DP. Genomic imprinting: a mammalian epigenetic discovery model. Annu Rev Genet. 2011;45:379-403.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21942369
2011
Bennett KL, Funk M, Tschernutter M, Breitwieser FP, Planyavsky M, Ubaida Mohien C, Muller A, Trajanoski Z, Colinge J, Superti-Furga G, Schmidt-Erfurth U. Proteomic analysis of human cataract aqueous humour: Comparison of one-dimensional gel LCMS with two-dimensional LCMS of unlabelled and iTRAQ(R)-labelled specimens. J Proteomics. 2011 Feb 1;74(2):151-66.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20940065
2011
Binder CJ, Witztum JL. Is atherosclerosis an allergic disease? Circ Res. 2011 Oct 28;109(10):1103-4.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22034478
2011
Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Ozturk M, Palkonen S, Prefaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schunemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski- Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C. Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med. 2011;3(7):43.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21745417
2011
Boztug K, Rosenberg PS, Dorda M, Banka S, Moulton T, Curtin J, Rezaei N, Corns J, Innis JW, Avci Z, Tran HC, Pellier I, Pierani P, Fruge R, Parvaneh N, Mamishi S, Mody R, Darbyshire P, Motwani J, Murray J, Buchanan GR, Newman WG, Alter BP, Boxer LA, Donadieu J, Welte K, Klein C. Extended Spectrum of Human Glucose-6-Phosphatase Catalytic Subunit 3 Deficiency: Novel Genotypes and Phenotypic Variability in Severe Congenital Neutropenia. J Pediatr. 2011 Nov 1.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22050868
2011
Breitwieser FP, Muller A, Dayon L, Kocher T, Hainard A, Pichler P, Schmidt- Erfurth U, Superti- Furga G, Sanchez JC, Mechtler K, Bennett KL, Colinge J. General statistical modeling of data from protein relative expression isobaric tags. J Proteome Res. 2011 Jun 3;10(6):2758-66.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21526793
2011
Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J. Initial characterization of the human central proteome. BMC Syst Biol. 2011;5:17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21269460
2011
Carette JE, Guimaraes CP, Wuethrich I, Blomen VA, Varadarajan M, Sun C, Bell G, Yuan B, Muellner MK, Nijman SM, Ploegh HL, Brummelkamp TR. Global gene disruption in human cells to assign genes to phenotypes by deep sequencing. Nat Biotechnol. 2011 Jun;29(6):542-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21623355
2011
Carillo S, Henry L, Lippert E, Girodon F, Guiraud I, Richard C, Dubois Galopin F, Cleyrat C, Jourdan E, Kralovics R, Hermouet S, Lavabre-Bertrand T. Nested high-resolution melting curve analysis a highly sensitive, reliable, and simple method for detection of JAK2 exon 12 mutations – clinical relevance in the monitoring of polycythemia. J Mol Diagn. 2011 May;13(3):263-70.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21497288
2011
Gleixner KV, Mayerhofer M, Cerny-Reiterer S, Hormann G, Rix U, Bennett KL, Hadzijusufovic E, Meyer RA, Pickl WF, Gotlib J, Horny HP, Reiter A, Mitterbauer-Hohendanner G, Superti-Furga G, Valent P. KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib. Blood. 2011 Aug 18;118(7):1885-98.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21680801
2011
Goncalves A, Burckstummer T, Dixit E, Scheicher R, Gorna MW, Karayel E, Sugar C, Stukalov A, Berg T, Kralovics R, Planyavsky M, Bennett KL, Colinge J, Superti-Furga G. Functional dissection of the TBK1 molecular network. PLoS One. 2011;6(9):e23971.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21931631
2011
Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P. Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection. PLoS Pathog. 2011 May;7(5):e1001345.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21625574
2011
Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G. Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell. 2011 Oct 14;147(2):306-19.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22000011
2011
Haider L, Fischer MT, Frischer JM, Bauer J, Hoftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H. Oxidative damage in multiple sclerosis lesions. Brain. 2011 Jul;134(Pt 7):1914-24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21653539
2011
Hantschel O, Grebien F, Superti-Furga G. Targeting allosteric regulatory modules in oncoproteins: “drugging the undruggable”. Oncotarget. 2011 Nov;2(11):828-9.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22084171
2011
Harutyunyan A, Gisslinger B, Klampfl T, Berg T, Bagienski K, Gisslinger H, Kralovics R. Rare germline variants in regions of loss of heterozygosity may influence clinical course of hematological malignancies. Leukemia. 2011 Nov;25(11):1782-4.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21681190
2011
Harutyunyan A, Klampfl T, Cazzola M, Kralovics R. p53 lesions in leukemic transformation. N Engl J Med. 2011 Feb 3;364(5):488-90.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21288114
2011
Haura EB, Muller A, Breitwieser FP, Li J, Grebien F, Colinge J, Bennett KL. Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer. J Proteome Res. 2011 Jan 7;10(1):182-90.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20945942
2011
Hayee B, Antonopoulos A, Murphy EJ, Rahman FZ, Sewell G, Smith BN, McCartney S, Furman M, Hall G, Bloom SL, Haslam SM, Morris HR, Boztug K, Klein C, Winchester B, Pick E, Linch DC, Gale RE, Smith AM, Dell A, Segal AW. G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction. Glycobiology. 2011 Jul;21(7):914-24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21385794
2011
Hoermann G, Cerny-Reiterer S, Perne A, Klauser M, Hoetzenecker K, Klein K, Mullauer L, Groger M, Nijman SM, Klepetko W, Valent P, Mayerhofer M. Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis. Am J Pathol. 2011 May;178(5):2344-56.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21457934
2011
Huang R, Jaritz M, Guenzl P, Vlatkovic I, Sommer A, Tamir IM, Marks H, Klampfl T, Kralovics R, Stunnenberg HG, Barlow DP, Pauler FM. An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One. 2011;6(11):e27288.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22102886
2011
Huber K, Superti-Furga G. After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders. Bioorg Med Chem. 2011 Jun 15;19(12):3616-24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21306906
2011
Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP. Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol. 2011 May 15;353(2):420-31.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21354127
2011
Jager R, Kralovics R. Molecular pathogenesis of Philadelphia chromosome negative chronic myeloproliferative neoplasms. Curr Cancer Drug Targets. 2011 Jan;11(1):20-30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21062246
2011
Klampfl T, Harutyunyan A, Berg T, Gisslinger B, Schalling M, Bagienski K, Olcaydu D, Passamonti F, Rumi E, Pietra D, Jager R, Pieri L, Guglielmelli P, Iacobucci I, Martinelli G, Cazzola M, Vannucchi AM, Gisslinger H, Kralovics R. Genome integrity of myeloproliferative neoplasms in chronic phase and during disease progression. Blood. 2011 Jul 7;118(1):167-76.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21531982
2011
Luo X, Liu Y, Kubicek S, Myllyharju J, Tumber A, Ng S, Che KH, Podoll J, Heightman TD, Oppermann U, Schreiber SL, Wang X. A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases. J Am Chem Soc. 2011 Jun 22;133(24):9451-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21585201
2011
Lutgens E, Binder CJ. Immunology of atherosclerosis. Thromb Haemost. 2011 Nov;106(5):755-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22011700
2011
Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res. 2011 Jan 21;108(2):235-48.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21252151
2011
Muellner MK, Uras IZ, Gapp BV, Kerzendorfer C, Smida M, Lechtermann H, Craig-Mueller N, Colinge J, Duernberger G, Nijman SM. A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer. Nat Chem Biol. 2011 Nov;7(11):787-93.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21946274
2011
Nijman SM. Synthetic lethality: general principles, utility and detection using genetic screens in human cells. FEBS Lett. 2011 Jan 3;585(1):1-6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21094158
2011
Olcaydu D, Rumi E, Harutyunyan A, Passamonti F, Pietra D, Pascutto C, Berg T, Jager R, Hammond E, Cazzola M, Kralovics R. The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms. Haematologica. 2011 Mar;96(3):367-74.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21173100
2011
Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T, Weber F, Colinge J, Muller M, Superti-Furga G. IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA. Nat Immunol. 2011 Jul;12(7):624-30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21642987
2011
Rumi E, Harutyunyan A, Elena C, Pietra D, Klampfl T, Bagienski K, Berg T, Casetti I, Pascutto C, Passamonti F, Kralovics R, Cazzola M. Identification of genomic aberrations associated with disease transformation by means of highresolution SNP array analysis in patients with myeloproliferative neoplasm. Am J Hematol. 2011 Dec;86(12): 974-9.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21953568
2011
Santoro F, Barlow DP. Developmental control of imprinted expression by macro non-coding RNAs. Semin Cell Dev Biol. 2011 Jun;22(4):328-35.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21333747
2011
Schneller D, Machat G, Sousek A, Proell V, van Zijl F, Zulehner G, Huber H, Mair M, Muellner MK, Nijman SM, Eferl R, Moriggl R, Mikulits W. p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma. Hepatology. 2011 Jul;54(1):164-72.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21452288
2011
Vilaine M, Olcaydu D, Harutyunyan A, Bergeman J, Tiab M, Ramee JF, Chen JM, Kralovics R, Hermouet S. Homologous recombination of wild-type JAK2, a novel early step in the development of myeloproliferative neoplasm. Blood. 2011 Dec 8;118(24):6468-70.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22161852
2011
Weber C, Meiler S, Doring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Forster I, Zenke M, Hieronymus T, Junt T, Zernecke A. CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J Clin Invest. 2011 Jul;121(7):2898-910.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21633167
2011
Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstatter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 2011 Oct 6;478(7367):76-81.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21979047
2011
Winter GE, Rix U, Lissat A, Stukalov A, Mullner MK, Bennett KL, Colinge J, Nijman SM, Kubicek S, Kovar H, Kontny U, Superti-Furga G. An integrated chemical biology approach identifies specific vulnerability of Ewing’s sarcoma to combined inhibition of Aurora kinases A and B. Mol Cancer Ther. 2011 Oct;10(10):1846-56.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21768330
2011
Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. FASEB J. 2011 Jan;25(1):290-300.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20876212
2011
Zimprich A, Benet-Pages A, Struhal W, Graf E, Eck SH, Offman MN, Haubenberger D, Spielberger S, Schulte EC, Lichtner P, Rossle SC, Klopp N, Wolf E, Seppi K, Pirker W, Presslauer S, Mollenhauer B, Katzenschlager R, Foki T, Hotzy C, Reinthaler E, Harutyunyan A, Kralovics R, Peters A, Zimprich F, Brucke T, Poewe W, Auff E, Trenkwalder C, Rost B, Ransmayr G, Winkelmann J, Meitinger T, Strom TM. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet. 2011 Jul 15;89(1):168-75.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21763483
2011
Zivkovic A, Sharif O, Stich K, Doninger B, Biaggio M, Colinge J, Bilban M, Mesteri I, Hazemi P, Lemmens-Gruber R, Knapp S. TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo. J Immunol. 2011 Feb 1;186(3):1608-17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21178007