Protein binder toolbox for studies of solute carrier transporters

Gastrointestinal biofilms - Endoscopic detection, disease relevance and therapeutic strategies

Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening

Monitoring subcellular protein localization at scale in live cells

Reticulated platelets in cirrhosis - Just a surrogate for thrombocytopenia?

Development of a live cell assay for the zinc transporter ZnT8

Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation

Genomic surveillance of SARS-CoV-2 evolution by a centralised pipeline and weekly focused sequencing, Austria, January 2021 to March 2023

The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity

AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells

A novel function of STAT3β in suppressing interferon response improves outcome in acute myeloid leukemia

Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy

Portal hypertension and its prognostic implications in patients with Wilson's disease

Breakthrough Infections in SARS-CoV-2-Vaccinated Multiple Myeloma Patients Improve Cross-Protection against Omicron Variants

Beyond the microscope: Unveiling bacterial vaginosis with AI-powered multiomics data analysis

Pan-cancer analysis of the interplay between mutational signatures and cellular signaling

In Vitro Investigation of Therapy-Induced Senescence and Senescence Escape in Breast Cancer Cells Using Novel Flow Cytometry-Based Methods

Mapping the brain's gene-regulatory maze

The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category

Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins

Image-based quantification of mitochondrial iron uptake via Mitoferrin-2

Very-early-onset Inflammatory Bowel Disease in an Infant with a Partial RIPK1 Deletion

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells

ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction

JAK-STAT signaling maintains homeostasis in T cells and macrophages

Oxidized phospholipids during microbial challenge: friend or foe?

Pooled multicolour tagging for visualizing subcellular protein dynamics

Expanding strategies to resolve psoriasis-like inflammation: Non-canonical NF-κB signaling controls IL-23 production in dendritic cells

Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia

A call for accessible tools to unlock single-cell immunometabolism research

Rapamycin Controls Lymphoproliferation and Reverses T-Cell Responses in a Patient with a Novel STIM1 Loss-of-Function Deletion

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo-rescence Microscopy

Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice

Extra centrosomes delay DNA damage-driven tumorigenesis

Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion

EU-LIFE charter of independent life science research institutes

The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertension

Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual

A single-center cohort study of patients with hereditary spherocytosis in Central Europe reveals a high frequency of novel disease-causing genotypes

A Novel Homozygous Six Base Pair Deletion Found in the NFATC2 Gene in a Patient with EBV-Associated Lymphoproliferation

Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease

Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8⁺ T cells

One-carbon metabolism nutrients impact the interplay between DNA methylation and gene expression in liver, enhancing protein synthesis in Atlantic salmon

Mechanical Actuation of Organoids in Synthetic Microenvironments

Targeted protein degradation via intramolecular bivalent glues

Reply: "Letter to the editor: Are we comparing apples with oranges?"

Aberrant Lipid Metabolism in Macrophages Is Associated with Granuloma Formation in Sarcoidosis

Author Correction: GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway

Navigating the thymic landscape through development: from cellular atlas to tissue cartography

FXR-FGF19 signaling in the gut-liver axis is dysregulated in patients with cirrhosis and correlates with impaired intestinal defence

Citizen neuroscience: Wearable technology and open software to study the human brain in its natural habitat

A high-resolution view of the heterogeneous aging endothelium

Multi-organ single-cell RNA sequencing in mice reveals early hyperglycemia responses that converge on fibroblast dysregulation

Efficacy and safety of mTOR inhibition in cutaneous sarcoidosis: a single-centre trial

Take my breath away-mitochondrial dysfunction drives CD8⁺ T cell exhaustion

Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity

Network cartographs for interpretable visualizations

Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders

Decreased platelet activation predicts hepatic decompensation and mortality in patients with cirrhosis

Sex-specific association of visceral and subcutaneous adipose tissue volumes with systemic inflammation and innate immune cells in people living with obesity

Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei

Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome

Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling

Multipotent progenitors instruct ontogeny of the superior colliculus

RIF1 regulates early replication timing in murine B cells

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8

A replicating LCMV-based vaccine for the treatment of solid tumors

Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis

Role of PDGFRA⁺ cells and a CD55⁺ PDGFRA^Lo fraction in the gastric mesenchymal niche

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Radiomic features define risk and are linked to DNA methylation attributes in primary CNS lymphoma

Using an embryo specific promoter to modify iron distribution pattern in Arabidopsis

Diverse macrophage populations contribute to distinct manifestations of human cutaneous graft-versus-host disease

2,4-Dichlorophenoxyacetic Acid Induces Degeneration of mDA Neurons In Vitro

Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis

Proximity-inducing pharmacology

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling

Novel CARMIL2 (RLTPR) Mutation Presenting with Hyper-IgE and Eosinophilia: A Case Report

Autoreactive T cells targeting type II pneumocyte antigens in COVID-19 convalescent patients

Metabolic support by macrophages sustains colonic epithelial homeostasis

The effect of leptin on trained innate immunity and on systemic inflammation in subjects with obesity

Mechanistic Study on Selenium- and Sulfur-Mediated Isomerization of Hydroxamic Acids

The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity

Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy

Heterogeneity in RAG1 and RAG2 deficiency: 35 cases from a single-centre

Identification of novel genetic loci for risk of multiple myeloma by functional annotation

Design principles for cyclin K molecular glue degraders

Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model

Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients

Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome

Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels

Pharmacological perturbation of the phase-separating protein SMNDC1

GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2^-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling

Low-dose Bisphenol A exposure alters the functionality and cellular environment in a human cardiomyocyte model

Structural and functional annotation of solute carrier transporters: implication for drug discovery

Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance

Cellular polyploidy in organ homeostasis and regeneration

Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors

Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis

You only waste twice: T cells in parasite-induced organ wasting

LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma

Complex interactions of cellular players in chronic Graft-versus-Host Disease

In vivo CRISPR/Cas9 screening identifies Pbrm1 as a regulator of myeloid leukemia development in mice

Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model

Phosphomevalonate kinase deficiency expands the genetic spectrum of systemic autoinflammatory diseases

Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis

Urethane functions can reduce metal salts under hydrothermal conditions: synthesis of noble metal nanoparticles on flexible sponges applied in semi-automated organic reduction

Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency

Cytokine-directed cellular cross-talk imprints synovial pathotypes in rheumatoid arthritis

Prioritization and functional validation of target genes from single-cell transcriptomics studies

Author Correction: A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology

Buffy coat signatures of breast cancer risk in a prospective cohort study

Screening Newborns for Low T Cell Receptor Excision Circles (TRECs) Fails to Detect Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome

Mast cell-derived BH4 is a critical mediator of postoperative pain

Severe congenital neutropenia due to G6PC3 deficiency: early and delayed phenotype of a patient

A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability

Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis

Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization

PRPF19 modulates morphology and growth behavior in a cell culture model of human skin

PRPF19 modulates morphology and growth behavior in a cell culture model of human skin

An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo

Novel patients with NHLRC2 variants expand the phenotypic spectrum of FINCA disease

Genotype-phenotype correlation in contactin-associated protein-like 2 (CNTNAP-2) developmental disorder

Novel patients with NHLRC2 variants expand the phenotypic spectrum of FINCA disease

Genotype-phenotype correlation in contactin-associated protein-like 2 (CNTNAP-2) developmental disorder

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?

Functional heterogeneity of human skin-resident memory T cells in health and disease

Functional heterogeneity of human skin-resident memory T cells in health and disease

Apoptotic cell death in disease-Current understanding of the NCCD 2023

Apoptotic cell death in disease-Current understanding of the NCCD 2023

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis

Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis

Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis

WAVES (Web-based tool for Analysis and Visualization of Environmental Samples)-a web application for visualization of wastewater pathogen sequencing results

WAVES (Web-based tool for Analysis and Visualization of Environmental Samples)-a web application for visualization of wastewater pathogen sequencing results

Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis

A progressive T cell exhaustion program mapped across tissues in patients with lung cancer on immune checkpoint blockade

A progressive T cell exhaustion program mapped across tissues in patients with lung cancer on immune checkpoint blockade

Assessment of community efforts to advance network-based prediction of protein-protein interactions

Assessment of community efforts to advance network-based prediction of protein-protein interactions

PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing

Good or bad cops: immune cells in aGVHD

Good or bad cops: immune cells in aGVHD

Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response

Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness

Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response

Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers

Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers

Therapeutic Potential of an Azithromycin-Colistin Combination against XDR K. pneumoniae in a 3D Collagen-Based In Vitro Wound Model of a Biofilm Infection

Polymerase-δ-deficiency as a novel cause of inborn cancer predisposition associated with human papillomavirus infection

Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

Polymerase-δ-deficiency as a novel cause of inborn cancer predisposition associated with human papillomavirus infection

Correction: Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target

In vivo screening unveils pervasive RNA-binding protein dependencies in leukemic stem cells and identifies ELAVL1 as a therapeutic target

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation

Macrophage and monocyte subsets as new therapeutic targets in cancer immunotherapy

Macrophage and monocyte subsets as new therapeutic targets in cancer immunotherapy

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence

Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence

LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data

Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation

LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data

Epigenetic regulation of T cell lineages in skin and blood following hematopoietic stem cell transplantation

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

Dual redox-active porous polyimides as high performance and versatile electrode material for next-generation batteries

Dual redox-active porous polyimides as high performance and versatile electrode material for next-generation batteries

Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension

Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension

Apoptosis as a Barrier against CIN and Aneuploidy

Apoptosis as a Barrier against CIN and Aneuploidy

The 2000HIV study: Design, multi-omics methods and participant characteristics

The 2000HIV study: Design, multi-omics methods and participant characteristics

E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance

E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance

CIDE-stepping E3s

CIDE-stepping E3s

Novel PGM3 mutation in two siblings with combined immunodeficiency and childhood bullous pemphigoid: a case report and review of the literature

Novel PGM3 mutation in two siblings with combined immunodeficiency and childhood bullous pemphigoid: a case report and review of the literature

VirPool: model-based estimation of SARS-CoV-2 variant proportions in wastewater samples

VirPool: model-based estimation of SARS-CoV-2 variant proportions in wastewater samples

Stress signaling boosts interferon-induced gene transcription in macrophages

Metabolic modulation of transcription: The role of one-carbon metabolism

Spatial omics technologies at multimodal and single cell/subcellular level

Stress signaling boosts interferon-induced gene transcription in macrophages

Metabolic modulation of transcription: The role of one-carbon metabolism

Spatial omics technologies at multimodal and single cell/subcellular level

Persistent alveolar type 2 dysfunction and lung structural derangement in post-acute COVID-19

Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease

In Vivo Modeling of CLL Transformation to Richter Syndrome Reveals Convergent Evolutionary Paths and Therapeutic Vulnerabilities

Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease

Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity

Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity

Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.

Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging

Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging

POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms

Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia

Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

TMBIM5 is the Ca²⁺ /H⁺ antiporter of mammalian mitochondria

TMBIM5 is the Ca²⁺ /H⁺ antiporter of mammalian mitochondria

Unsupervised discovery of tissue architecture in multiplexed imaging

Unsupervised discovery of tissue architecture in multiplexed imaging

(Not) Home alone: Antigen presenting cell - T Cell communication in barrier tissues

(Not) Home alone: Antigen presenting cell - T Cell communication in barrier tissues

Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

Leptin increases hepatic triglyceride export via a vagal mechanism in humans

Leptin increases hepatic triglyceride export via a vagal mechanism in humans

A structure and evolutionary-based classification of solute carriers

Imaging features facilitate diagnosis of porto-sinusoidal vascular disorder

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission

A structure and evolutionary-based classification of solute carriers

Imaging features facilitate diagnosis of porto-sinusoidal vascular disorder

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

Case Report: Susceptibility to viral infections and secondary hemophagocytic lymphohistiocytosis responsive to intravenous immunoglobulin as primary manifestations of adenosine deaminase 2 deficiency

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

Case Report: Susceptibility to viral infections and secondary hemophagocytic lymphohistiocytosis responsive to intravenous immunoglobulin as primary manifestations of adenosine deaminase 2 deficiency

T-cell/histiocyte-rich large B-cell lymphoma in a patient with a novel frameshift MSH6 mutation

Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis

T-cell/histiocyte-rich large B-cell lymphoma in a patient with a novel frameshift MSH6 mutation

Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis

Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognized by CD8⁺ T Cells

Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognized by CD8⁺ T Cells

Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine

Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine

The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI

Comparison of clinical characteristics among patients infected with alpha vs. delta SARS-CoV-2 variants

Comparison of clinical characteristics among patients infected with alpha vs. delta SARS-CoV-2 variants

Co-expression of mutated Jak2 and Calr enhances myeloproliferative phenotype in mice without loss of stem cell fitness

Human repair-related Schwann cells adopt functions of antigen-presenting cells in vitro

Co-expression of mutated Jak2 and Calr enhances myeloproliferative phenotype in mice without loss of stem cell fitness

Human repair-related Schwann cells adopt functions of antigen-presenting cells in vitro

SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

Acknowledging and citing core facilities: Key contributions to data lifecycle should be recognised in the scientific literature: Key contributions to data lifecycle should be recognised in the scientific literature

Acknowledging and citing core facilities: Key contributions to data lifecycle should be recognised in the scientific literature: Key contributions to data lifecycle should be recognised in the scientific literature

A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation

A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation

Low-grade inflammation as mediator between diet and behavioral disinhibition: A UK Biobank study

Accelerating SLC Transporter Research: Streamlining Knowledge and Validated Tools

Accelerating SLC Transporter Research: Streamlining Knowledge and Validated Tools

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets

FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder

FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells

Synthesis of α-Aryl Acrylamides via Lewis-Base-Mediated Aryl/Hydrogen Exchange

Synthesis of α-Aryl Acrylamides via Lewis-Base-Mediated Aryl/Hydrogen Exchange

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale

Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale

Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells

Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells

Systemic inflammation is linked to liver fibrogenesis in patients with advanced chronic liver disease

Systemic inflammation is linked to liver fibrogenesis in patients with advanced chronic liver disease

Case Report: Refractory Cytopenia With a Switch From a Transient Monosomy 7 to a Disease-Ameliorating del(20q) in a NHEJ1-Deficient Long-term Survivor

Case Report: Refractory Cytopenia With a Switch From a Transient Monosomy 7 to a Disease-Ameliorating del(20q) in a NHEJ1-Deficient Long-term Survivor

BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph⁺ chronic myeloid leukemia

BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph⁺ chronic myeloid leukemia

Processing human skin samples for single-cell assays

Processing human skin samples for single-cell assays

Accumulation of Cytotoxic Skin Resident Memory T Cells and Increased Expression of IL-15 in Lesional Skin of Polymorphic Light Eruption

Accumulation of Cytotoxic Skin Resident Memory T Cells and Increased Expression of IL-15 in Lesional Skin of Polymorphic Light Eruption

Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

PCfun: a hybrid computational framework for systematic characterization of protein complex function

Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR-based screens

Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR-based screens

Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells

Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells

Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters

Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters

Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis

Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease

Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study

Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study

The Spectrum of B Cell Functions in Atherosclerotic Cardiovascular Disease

SvAnna: efficient and accurate pathogenicity prediction of coding and regulatory structural variants in long-read genome sequencing

The miR-26 family regulates early B cell development and transformation

The miR-26 family regulates early B cell development and transformation

Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease

Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease

Case Report of a Novel NFkB Mutation in a Lymphoproliferative Disorder Patient

Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound

Case Report of a Novel NFkB Mutation in a Lymphoproliferative Disorder Patient

Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound

Angiopoietin 2 levels decrease after HCV-cure and reflect the evolution of portal hypertension

Angiopoietin 2 levels decrease after HCV-cure and reflect the evolution of portal hypertension

PIDD1 in cell cycle control, sterile inflammation and cell death

PIDD1 in cell cycle control, sterile inflammation and cell death

CDK6 Degradation Is Counteracted by p16^INK4A and p18^INK4C in AML

Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila

Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila

Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data

Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data

Chronic or severe enteropathy and immunodeficiency: be prepared for a rara avis

Chronic or severe enteropathy and immunodeficiency: be prepared for a rara avis

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

Splenectomy ameliorates portal pressure and anemia in animal models of cirrhotic and non-cirrhotic portal hypertension

Splenectomy ameliorates portal pressure and anemia in animal models of cirrhotic and non-cirrhotic portal hypertension

A novel approach to the functional classification of retinal ganglion cells

Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes

Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes

Targeting solute carriers to modulate receptor-ligand interactions

Targeting solute carriers to modulate receptor-ligand interactions

Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

Target 2035 - update on the quest for a probe for every protein

Target 2035 - update on the quest for a probe for every protein

Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

Rapid neutrophil mobilisation by VCAM-1+ endothelial extracellular vesicles

Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency

Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function

Oncogenic TYK2^P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

The regulatory network architecture of cardiometabolic diseases

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

PD-L1 overexpression correlates with JAK2-V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasms

Leu226Trp CACNA1A variant associated with juvenile myoclonic epilepsy with and without intellectual disability

Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions

Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression

Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis

Roles of SETD2 in Leukemia-Transcription, DNA-Damage, and Beyond

SETD2 in MLL-rearranged leukemia - a complex case

Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

STAT5BN642H is a driver mutation for T cell neoplasia

Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site

Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

STAT3 regulated ARF expression suppresses prostate cancer metastasis

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Affinity purification strategies for proteomic analysis of transcription factor complexes

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

Using iTRAQ combined with tandem affinity purification to enhance low-abundance proteins associated with somatically mutated EGFR core complexes in lung cancer