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Year
Paper
2022

Imaging features facilitate diagnosis of porto-sinusoidal vascular disorder

Katharina Lampichler, Georg Semmler, Katharina Wöran, Benedikt Simbrunner, Mathias Jachs, Lukas Hartl, David Josef Maria Bauer, Lorenz Balcar, Lukas Burghart, Michael Trauner, Dietmar Tamandl, Ahmed Ba-Ssalamah, Mattias Mandorfer, Thomas Reiberger, Bernhard Scheiner, Martina Scharitzer.
Eur Radiol. 2022 Sep 27. doi: 10.1007/s00330-022-09132-4. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36166087/
2022

A structure and evolutionary-based classification of solute carriers

Evandro Ferrada, Giulio Superti-Furga.
iScience. 2022 Sep 8;25(10):105096. doi: 10.1016/j.isci.2022.105096. eCollection 2022 Oct 21.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36164651/
2022

Case Report: Susceptibility to viral infections and secondary hemophagocytic lymphohistiocytosis responsive to intravenous immunoglobulin as primary manifestations of adenosine deaminase 2 deficiency

Enrico Drago, Francesca Garbarino, Sara Signa, Alice Grossi, Francesca Schena, Federica Penco, Elettra Santori, Fabio Candotti, Kaan Boztug, Stefano Volpi, Marco Gattorno, Roberta Caorsi.
Front Immunol. 2022 Sep 9;13:937108. doi: 10.3389/fimmu.2022.937108. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36159847/
2022

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

Antigoni Gogolou, Celine Souilhol, Ilaria Granata, Filip J Wymeersch, Ichcha Manipur, Matthew Wind, Thomas J R Frith, Maria Guarini, Alessandro Bertero, Christoph Bock, Florian Halbritter, Minoru Takasato, Mario R Guarracino, Anestis Tsakiridis.
Elife. 2022 Sep 26;11:e74263. doi: 10.7554/eLife.74263.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36154671/
2022

Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis

Jiří Reiniš, Oleksandr Petrenko, Benedikt Simbrunner, Benedikt S Hofer, Filippo Schepis, Marco Scoppettuolo, Dario Saltini, Federica Indulti, Tomas Guasconi, Agustin Albillos, Luis Téllez, Càndid Villanueva, Anna Brujats, Juan Carlos Garcia-Pagan, Valeria Perez-Campuzano, Virginia Hernández-Gea, Pierre-Emmanuel Rautou, Lucile Moga, Thomas Vanwolleghem, Wilhelmus J Kwanten, Sven Francque, Jonel Trebicka, Wenyi Gu, Philip G Ferstl, Lise Lotte Gluud, Flemming Bendtsen, Søren Møller, Stefan Kubicek, Mattias Mandorfer, Thomas Reiberger.
J Hepatol. 2022 Sep 21:S0168-8278(22)03119-1. doi: 10.1016/j.jhep.2022.09.012. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36152767/
2022

T-cell/histiocyte-rich large B-cell lymphoma in a patient with a novel frameshift MSH6 mutation

Sukru Cekic, Firdevs Aydin, Yasin Karali, Betül Berrin Sevinir, Ozlem Canoz, Kaan Boztug, Ekrem Unal, Sara Sebnem Kilic.
Pediatr Blood Cancer. 2022 Sep 24:e30008. doi: 10.1002/pbc.30008. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36151955/
2022

Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine

Tim Heinemann, Christoph Kornauth, Yannik Severin, Gregory I Vladimer, Tea Pemovska, Emir Hadzijusufovic, Hermine Agis, Maria-Theresa Krauth, Wolfgang R Sperr, Peter Valent, Ulrich Jäger, Ingrid Simonitsch-Klupp, Giulio Superti-Furga, Philipp B Staber, Berend Snijder.
Blood Cancer Discov. 2022 Nov 2;3(6):502-515. doi: 10.1158/2643-3230.BCD-21-0219.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36125297/
2022

Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

Manuele Rebsamen, Enrico Girardi, Vitaly Sedlyarov, Stefania Scorzoni, Konstantinos Papakostas, Manuela Vollert, Justyna Konecka, Bettina Guertl, Kristaps Klavins, Tabea Wiedmer, Giulio Superti-Furga.
Life Sci Alliance. 2022 Sep 16;5(11):e202201404. doi: 10.26508/lsa.202201404. Print 2022 Nov.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36114003/
2022

The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

Katharina Hutter, Thomas Rülicke, Tamas G Szabo, Lill Andersen, Andreas Villunger, Sebastian Herzog.
Front Immunol. 2022 Aug 25;13:967914. doi: 10.3389/fimmu.2022.967914. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36110849/
2022

Comparison of clinical characteristics among patients infected with alpha vs. delta SARS-CoV-2 variants

Benedikt Rumpf, Benno Lickefett, Clemens Baumgartner, Victoria Kauer, Mario Karolyi, Erich Pawelka, Tamara Seitz, Marianna Traugott, Petr Triska, Andreas Bergthaler, Hermann Laferl, Christoph Wenisch, Alexander Zoufaly.
Wien Klin Wochenschr. 2022 Sep 7:1-6. doi: 10.1007/s00508-022-02084-1. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36070027/
2022

Human repair-related Schwann cells adopt functions of antigen-presenting cells in vitro

Jakob Berner, Tamara Weiss, Helena Sorger, Fikret Rifatbegovic, Max Kauer, Reinhard Windhager, Alexander Dohnal, Peter F Ambros, Inge M Ambros, Kaan Boztug, Peter Steinberger, Sabine Taschner-Mandl.
Glia. 2022 Dec;70(12):2361-2377. doi: 10.1002/glia.24257. Epub 2022 Aug 17.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36054432/
2022

Co-expression of mutated Jak2 and Calr enhances myeloproliferative phenotype in mice without loss of stem cell fitness

Christina M Schueller, Andrea Majoros, Harini Nivarthi, Robert Kralovics.
Am J Hematol. 2022 Nov;97(11):E396-E399. doi: 10.1002/ajh.26688. Epub 2022 Aug 30.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36053947/
2022

SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

Tamara Casteels, Simon Bajew, Jiří Reiniš, Lennart Enders, Michael Schuster, Frédéric Fontaine, André C Müller, Bridget K Wagner, Christoph Bock, Stefan Kubicek.
Cell Rep. 2022 Aug 30;40(9):111288. doi: 10.1016/j.celrep.2022.111288.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36044849/
2022

PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis

Ju Youn Kim, Lily Q Wang, Valentina C Sladky, Tae Gyu Oh, Junlai Liu, Kaitlyn Trinh, Felix Eichin, Michael Downes, Mojgan Hosseini, Etienne D Jacotot, Ronald M Evans, Andreas Villunger, Michael Karin.
Cell Metab. 2022 Oct 4;34(10):1548-1560.e6. doi: 10.1016/j.cmet.2022.08.005. Epub 2022 Aug 29.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36041455/
2022

Acknowledging and citing core facilities: Key contributions to data lifecycle should be recognised in the scientific literature: Key contributions to data lifecycle should be recognised in the scientific literature

Katja Kivinen, Henri G A M van Luenen, Myriam Alcalay, Christoph Bock, Joanna Dodzian, Katerina Hoskova, Danielle Hoyle, Ondrej Hradil, Sofie Kjellerup Christensen, Bernhard Korn, Theodoros Kosteas, Mònica Morales, Krzysztof Skowronek, Vasiliki Theodorou, Geert Van Minnebruggen, Jean Salamero, Lavanya Premvardhan.
EMBO Rep. 2022 Sep 5;23(9):e55734. doi: 10.15252/embr.202255734. Epub 2022 Aug 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35997112/
2022

A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation

Lena Hess, Verena Moos, Arnel A Lauber, Wolfgang Reiter, Michael Schuster, Natascha Hartl, Daniel Lackner, Thorina Boenke, Anna Koren, Paloma M Guzzardo, Brigitte Gundacker, Anna Riegler, Petra Vician, Claudia Miccolo, Susanna Leiter, Mahesh B Chandrasekharan, Terezia Vcelkova, Andrea Tanzer, Jun Qi Jun, James Bradner, Gerald Brosch, Markus Hartl, Christoph Bock, Tilmann Bürckstümmer, Stefan Kubicek, Susanna Chiocca, Srividya Bhaskara, Christian Seiser.
PLoS Genet. 2022 Aug 22;18(8):e1010376. doi: 10.1371/journal.pgen.1010376. eCollection 2022 Aug.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35994477/
2022

Accelerating SLC Transporter Research: Streamlining Knowledge and Validated Tools

Tabea Wiedmer, Alvaro Ingles-Prieto, Ulrich Goldmann, Claire M Steppan, Giulio Superti-Furga, RESOLUTE, REsolution consortia.
Clin Pharmacol Ther. 2022 Sep;112(3):439-442. doi: 10.1002/cpt.2639. Epub 2022 Aug 8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35938294/
2022

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets

Ábel Vértesy, Oliver L Eichmüller, Julia Naas, Maria Novatchkova, Christopher Esk, Meritxell Balmaña, Sabrina Ladstaetter, Christoph Bock, Arndt von Haeseler, Juergen A Knoblich.
EMBO J. 2022 Sep 1;41(17):e111118. doi: 10.15252/embj.2022111118. Epub 2022 Aug 2.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35919947/
2022

FIBCD1 is an endocytic GAG receptor associated with a novel neurodevelopmental disorder

Christopher W Fell, Astrid Hagelkruys, Ana Cicvaric, Marion Horrer, Lucy Liu, Joshua Shing Shun Li, Johannes Stadlmann, Anton A Polyansky, Stefan Mereiter, Miguel Angel Tejada, Tomislav Kokotović, Venkat Swaroop Achuta, Angelica Scaramuzza, Kimberly A Twyman, Michelle M Morrow, Jane Juusola, Huifang Yan, Jingmin Wang, Margit Burmeister, Biswa Choudhury, Thomas Levin Andersen, Gerald Wirnsberger, Uffe Holmskov, Norbert Perrimon, Bojan Žagrović, Francisco J Monje, Jesper Bonnet Moeller, Josef M Penninger, Vanja Nagy.
EMBO Mol Med. 2022 Sep 7;14(9):e15829. doi: 10.15252/emmm.202215829. Epub 2022 Aug 2.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35916241/
2022

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

Cathrine Nordgaard, Anna Constance Vind, Amy Stonadge, Rasmus Kjøbsted, Goda Snieckute, Pedro Antas, Melanie Blasius, Marie Sofie Reinert, Ana Martinez Del Val, Dorte Breinholdt Bekker-Jensen, Peter Haahr, Yekaterina A Miroshnikova, Abdelghani Mazouzi, Sarah Falk, Emeline Perrier-Groult, Christopher Tiedje, Xiang Li, Jens Rithamer Jakobsen, Nicolas Oldenburg Jørgensen, Jørgen Fp Wojtaszewski, Frederic Mallein-Gerin, Jesper Løvind Andersen, Cristian Pablo Pennisi, Christoffer Clemmensen, Moustapha Kassem, Abbas Jafari, Thijn Brummelkamp, Vivian Sw Li, Sara A Wickström, Jesper Velgaard Olsen, Gonzalo Blanco, Simon Bekker-Jensen.
EMBO J. 2022 Sep 1;41(17):e111650. doi: 10.15252/embj.2022111650. Epub 2022 Jul 28.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35899396/
2022

Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells

Barbara Uhl, Katharina T Prochazka, Katrin Pansy, Kerstin Wenzl, Johanna Strobl, Claudia Baumgartner, Marta M Szmyra, James E Waha, Axel Wolf, Peter V Tomazic, Elisabeth Steinbauer, Maria Steinwender, Sabine Friedl, Marc Weniger, Ralf Küppers, Martin Pichler, Hildegard T Greinix, Georg Stary, Alan G Ramsay, Benedetta Apollonio, Julia Feichtinger, Christine Beham-Schmid, Peter Neumeister, Alexander J Deutsch.
Int J Mol Sci. 2022 Jul 17;23(14):7874. doi: 10.3390/ijms23147874.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35887224/
2022

Synthesis of α-Aryl Acrylamides via Lewis-Base-Mediated Aryl/Hydrogen Exchange

Miran Lemmerer, Haoqi Zhang, Anthony J Fernandes, Tobias Fischer, Marianne Mießkes, Yi Xiao, Nuno Maulide.
Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202207475. doi: 10.1002/anie.202207475. Epub 2022 Aug 29.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35881564/
2022

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

Sophie Zahalka, Philipp Starkl, Martin L Watzenboeck, Asma Farhat, Mariem Radhouani, Florian Deckert, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Caroline Lassnig, Birgit Strobl, Kristaps Klavins, Mai Matsushita, David E Sanin, Katarzyna M Grzes, Edward J Pearce, Anna-Dorothea Gorki, Sylvia Knapp.
Mucosal Immunol. 2022 May;15(5):896-907. doi: 10.1038/s41385-022-00528-5. Epub 2022 Jul 18.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35856089/
2022

Viral variant-resolved wastewater surveillance of SARS-CoV-2 at national scale

Fabian Amman, Rudolf Markt, Lukas Endler, Sebastian Hupfauf, Benedikt Agerer, Anna Schedl, Lukas Richter, Melanie Zechmeister, Martin Bicher, Georg Heiler, Petr Triska, Matthew Thornton, Thomas Penz, Martin Senekowitsch, Jan Laine, Zsofia Keszei, Peter Klimek, Fabiana Nägele, Markus Mayr, Beatrice Daleiden, Martin Steinlechner, Harald Niederstätter, Petra Heidinger, Wolfgang Rauch, Christoph Scheffknecht, Gunther Vogl, Günther Weichlinger, Andreas Otto Wagner, Katarzyna Slipko, Amandine Masseron, Elena Radu, Franz Allerberger, Niki Popper, Christoph Bock, Daniela Schmid, Herbert Oberacher, Norbert Kreuzinger, Heribert Insam, Andreas Bergthaler.
Nat Biotechnol. 2022 Jul 18. doi: 10.1038/s41587-022-01387-y. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35851376/
2022

Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells

Stuti Mehta, Altantsetseg Buyanbat, Yan Kai, Ozge Karayel, Seth Raphael Goldman, Davide Seruggia, Kevin Zhang, Yuko Fujiwara, Katherine A Donovan, Qian Zhu, Huan Yang, Behnam Nabet, Nathanael S Gray, Matthias Mann, Eric S Fischer, Karen Adelman, Stuart H Orkin.
Cell Chem Biol. 2022 Aug 18;29(8):1273-1287.e8. doi: 10.1016/j.chembiol.2022.06.007. Epub 2022 Jul 14.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35839780/
2022

Systemic inflammation is linked to liver fibrogenesis in patients with advanced chronic liver disease

Benedikt Simbrunner, Ida Falk Villesen, Philipp Königshofer, Bernhard Scheiner, David Bauer, Rafael Paternostro, Philipp Schwabl, Gerald Timelthaler, Dariga Ramazanova, Katharina Wöran, Judith Stift, Ernst Eigenbauer, Albert Friedrich Stättermayer, Rodrig Marculescu, Matthias Pinter, Søren Møller, Michael Trauner, Morten Karsdal, Diana Julie Leeming, Thomas Reiberger, Mattias Mandorfer.
Liver Int. 2022 Nov;42(11):2501-2512. doi: 10.1111/liv.15365. Epub 2022 Aug 25.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35822301/
2022

Case Report: Refractory Cytopenia With a Switch From a Transient Monosomy 7 to a Disease-Ameliorating del(20q) in a NHEJ1-Deficient Long-term Survivor

Fiona Poyer, Raúl Jimenez Heredia, Wolfgang Novak, Petra Zeitlhofer, Karin Nebral, Michael N Dworzak, Oskar A Haas, Kaan Boztug, Leo Kager.
Front Immunol. 2022 Jun 24;13:869047. doi: 10.3389/fimmu.2022.869047. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35812385/
2022

BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph+ chronic myeloid leukemia

Barbara Peter, Gregor Eisenwort, Irina Sadovnik, Karin Bauer, Michael Willmann, Thomas Rülicke, Daniela Berger, Gabriele Stefanzl, Georg Greiner, Gregor Hoermann, Alexandra Keller, Dominik Wolf, Martin Čulen, Georg E Winter, Thomas Hoffmann, Ana-Iris Schiefer, Wolfgang R Sperr, Johannes Zuber, Jiří Mayer, Peter Valent.
Am J Hematol. 2022 Sep;97(9):1215-1225. doi: 10.1002/ajh.26650. Epub 2022 Jul 18.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35794848/
2022

Processing human skin samples for single-cell assays

Simona Saluzzo, Laura Marie Gail, Teresa Neuwirth, Ram Vinay Pandey, Matthias Farlik, Georg Stary.
STAR Protoc. 2022 Jun 17;3(3):101470. doi: 10.1016/j.xpro.2022.101470. eCollection 2022 Sep 16.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35769924/
2022

Accumulation of Cytotoxic Skin Resident Memory T Cells and Increased Expression of IL-15 in Lesional Skin of Polymorphic Light Eruption

VijayKumar Patra, Johanna Strobl, Denise Atzmüller, Bärbel Reininger, Lisa Kleissl, Alexandra Gruber-Wackernagel, Jean-Francois Nicolas, Georg Stary, Marc Vocanson, Peter Wolf.
Front Med (Lausanne). 2022 Jun 10;9:908047. doi: 10.3389/fmed.2022.908047. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35755042/
2022

Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

Amandine Moretton, Jana Slyskova, Marwan E Simaan, Emili A Arasa-Verge, Mathilde Meyenberg, D Alonso Cerrón-Infantes, Miriam M Unterlass, Joanna I Loizou.
Front Oncol. 2022 Jun 2;12:874201. doi: 10.3389/fonc.2022.874201. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35719993/
2022

Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR-based screens

Jordan Wilson, Joanna I Loizou.
Mol Oncol. 2022 Jun 16. doi: 10.1002/1878-0261.13272. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35708734/
2022

Genetic tracing reveals transcription factor Foxp3-dependent and Foxp3-independent functionality of peripherally induced Treg cells

Joris van der Veeken, Clarissa Campbell, Yuri Pritykin, Michail Schizas, Jacob Verter, Wei Hu, Zhong-Min Wang, Fanny Matheis, Daniel Mucida, Louis-Marie Charbonnier, Talal A Chatila, Alexander Y Rudensky.
Immunity. 2022 Jul 12;55(7):1173-1184.e7. doi: 10.1016/j.immuni.2022.05.010. Epub 2022 Jun 13.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35700740/
2022

Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate Transporters

Hubert J Sijben, Laura Dall' Acqua, Rongfang Liu, Abigail Jarret, Eirini Christodoulaki, Svenja Onstein, Gernot Wolf, Simone J Verburgt, Sylvia E Le Dévédec, Tabea Wiedmer, Giulio Superti-Furga, Adriaan P IJzerman, Laura H Heitman.
Front Pharmacol. 2022 May 23;13:872335. doi: 10.3389/fphar.2022.872335. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35677430/
2022

Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis

Hidde Douna, Virginia Smit, Gijs H M van Puijvelde, Mate G Kiss, Christoph J Binder, Llze Bot, Vijay K Kuchroo, Andrew H Lichtman, Johan Kuiper, Amanda C Foks.
Atherosclerosis. 2022 Jul;352:1-9. doi: 10.1016/j.atherosclerosis.2022.05.017. Epub 2022 May 21.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35636144/
2022

Network Approaches for Charting the Transcriptomic and Epigenetic Landscape of the Developmental Origins of Health and Disease

Salvo Danilo Lombardo, Ivan Fernando Wangsaputra, Jörg Menche, Adam Stevens.
Genes (Basel). 2022 Apr 26;13(5):764. doi: 10.3390/genes13050764.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35627149/
2022

The miR-26 family regulates early B cell development and transformation

Katharina Hutter, Silke E Lindner, Constanze Kurschat, Thomas Rülicke, Andreas Villunger, Sebastian Herzog.
Life Sci Alliance. 2022 Apr 22;5(8):e202101303. doi: 10.26508/lsa.202101303. Print 2022 Aug.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35459737/
2022

Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease

Christine Bangert, Sergio Villazala-Merino, Martin Fahrenberger, Thomas Krausgruber, Wolfgang M Bauer, Victoria Stanek, Nicholas James Campion, Tina Bartosik, Tamara Quint, Guenther Regelsberger, Verena Niederberger-Leppin, Christoph Bock, Sven Schneider, Julia Eckl-Dorna.
Front Immunol. 2022 Mar 28;13:850494. doi: 10.3389/fimmu.2022.850494. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35418991/
2022

Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound

Iris E Ertl, Ursula Lemberger, Dafina Ilijazi, Melanie R Hassler, Andreas Bruchbacher, Robert Brettner, Hannah Kronabitter, Michael Gutmann, Petra Vician, Gerhard Zeitler, Anna Koren, Charles-Hugues Lardeau, Thomas Mohr, Andrea Haitel, Eva Compérat, André Oszwald, Gabriel Wasinger, Thomas Clozel, Olivier Elemento, Stefan Kubicek, Walter Berger, Shahrokh F Shariat.
Eur Urol. 2022 Sep;82(3):261-270. doi: 10.1016/j.eururo.2022.03.009. Epub 2022 Apr 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35393162/
2022

Case Report of a Novel NFkB Mutation in a Lymphoproliferative Disorder Patient

Khashayar Danandeh, Parnian Jabbari, Elham Rayzan, Samaneh Zoghi, Sepideh Shahkarami, Raul Jimenez Heredia, Ana Krolo, Bibi Shahin Shamsian, Kaan Boztug, Nima Rezaei.
Endocr Metab Immune Disord Drug Targets. 2022;22(10):1040-1046. doi: 10.2174/1871530322666220407091356.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35392793/
2022

Angiopoietin 2 levels decrease after HCV-cure and reflect the evolution of portal hypertension

David Bauer, Karin Kozbial, Philipp Schwabl, David Chromy, Benedikt Simbrunner, Albert F Stättermayer, Matthias Pinter, Petra Steindl-Munda, Michael Trauner, Peter Ferenci, Thomas Reiberger, Mattias Mandorfer.
Dig Liver Dis. 2022 Sep;54(9):1222-1229. doi: 10.1016/j.dld.2022.02.013. Epub 2022 Apr 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35382974/
2022

PIDD1 in cell cycle control, sterile inflammation and cell death

Elias S Weiler, Tamas G Szabo, Irmina Garcia-Carpio, Andreas Villunger.
Biochem Soc Trans. 2022 Apr 29;50(2):813-824. doi: 10.1042/BST20211186.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35343572/
2022

Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila

Shamsi Emtenani, Elliot T Martin, Attila Gyoergy, Julia Bicher, Jakob-Wendelin Genger, Thomas Köcher, Maria Akhmanova, Mariana Guarda, Marko Roblek, Andreas Bergthaler, Thomas R Hurd, Prashanth Rangan, Daria E Siekhaus.
EMBO J. 2022 Jun 14;41(12):e109049. doi: 10.15252/embj.2021109049. Epub 2022 Mar 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35319107/
2022

Emergence of SARS-CoV-2 Alpha lineage and its correlation with quantitative wastewater-based epidemiology data

Elena Radu, Amandine Masseron, Fabian Amman, Anna Schedl, Benedikt Agerer, Lukas Endler, Thomas Penz, Christoph Bock, Andreas Bergthaler, Julia Vierheilig, Peter Hufnagl, Irina Korschineck, Jörg Krampe, Norbert Kreuzinger.
Water Res. 2022 May 15;215:118257. doi: 10.1016/j.watres.2022.118257. Epub 2022 Mar 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35303559/
2022

Chronic or severe enteropathy and immunodeficiency: be prepared for a rara avis

Katrin Weber, Yvonne Zeißig, Cornelie Haag, Renate Schmelz, Julia Pazmandi, Artem Kalinichenko, Kaan Boztug, Sebastian Zeißig, Daniela Aust, Martin W Laass, Catharina Schuetz.
Z Gastroenterol. 2022 Mar 16. doi: 10.1055/a-1709-5024. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35297030/
2022

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes

Denis Seyres, Alessandra Cabassi, John J Lambourne, Frances Burden, Samantha Farrow, Harriet McKinney, Joana Batista, Carly Kempster, Maik Pietzner, Oliver Slingsby, Thong Huy Cao, Paulene A Quinn, Luca Stefanucci, Matthew C Sims, Karola Rehnstrom, Claire L Adams, Amy Frary, Bekir Ergüener, Roman Kreuzhuber, Gabriele Mocciaro, Simona D'Amore, Albert Koulman, Luigi Grassi, Julian L Griffin, Leong Loke Ng, Adrian Park, David B Savage, Claudia Langenberg, Christoph Bock, Kate Downes, Nicholas J Wareham, Michael Allison, Michele Vacca, Paul D W Kirk, Mattia Frontini.
Clin Epigenetics. 2022 Mar 12;14(1):39. doi: 10.1186/s13148-022-01257-z.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35279219/
2022

Splenectomy ameliorates portal pressure and anemia in animal models of cirrhotic and non-cirrhotic portal hypertension

Philipp Schwabl, Berit Anna Seeland, Florian Riedl, Tim Lukas Schubert, Philipp Königshofer, Ksenia Brusilovskaya, Oleksandr Petrenko, Benedikt Hofer, Ana-Iris Schiefer, Michael Trauner, Markus Peck-Radosavljevic, Thomas Reiberger.
Adv Med Sci. 2022 Mar;67(1):154-162. doi: 10.1016/j.advms.2022.02.005. Epub 2022 Mar 8.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35272246/
2022

Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes

Georg A Busslinger.
Mol Cell Oncol. 2022 Jan 22;9(1):2026559. doi: 10.1080/23723556.2022.2026559. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35252552/
2022

Targeting solute carriers to modulate receptor-ligand interactions

Hubert J Sijben, Giulio Superti-Furga, Adriaan P IJzerman, Laura H Heitman.
Trends Pharmacol Sci. 2022 May;43(5):358-361. doi: 10.1016/j.tips.2022.02.004. Epub 2022 Feb 26.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35232590/
2022

Target 2035 - update on the quest for a probe for every protein

Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al-Lazikani, Albert Antolin, Jonathan B Baell, Hartmut Beck, Shaunna Beedie, Ulrich A K Betz, Gustavo Arruda Bezerra, Paul E Brennan, David Brown, Peter J Brown, Alex N Bullock, Adrian J Carter, Apirat Chaikuad, Mathilde Chaineau, Alessio Ciulli, Ian Collins, Jan Dreher, David Drewry, Kristina Edfeldt, Aled M Edwards, Ursula Egner, Stephen V Frye, Stephen M Fuchs, Matthew D Hall, Ingo V Hartung, Alexander Hillisch, Stephen H Hitchcock, Evert Homan, Natarajan Kannan, James R Kiefer, Stefan Knapp, Milka Kostic, Stefan Kubicek, Andrew R Leach, Sven Lindemann, Brian D Marsden, Hisanori Matsui, Jordan L Meier, Daniel Merk, Maurice Michel, Maxwell R Morgan, Anke Mueller-Fahrnow, Dafydd R Owen, Benjamin G Perry, Saul H Rosenberg, Kumar Singh Saikatendu, Matthieu Schapira, Cora Scholten, Sujata Sharma, Anton Simeonov, Michael Sundström, Giulio Superti-Furga, Matthew H Todd, Claudia Tredup, Masoud Vedadi, Frank von Delft, Timothy M Willson, Georg E Winter, Paul Workman, Cheryl H Arrowsmith.
RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35211674/
2022

Long-term outcomes of polycythemia vera patients treated with ropeginterferon Alfa-2b

Jean-Jacques Kiladjian, Christoph Klade, Pencho Georgiev, Dorota Krochmalczyk, Liana Gercheva-Kyuchukova, Miklos Egyed, Petr Dulicek, Arpad Illes, Halyna Pylypenko, Lylia Sivcheva, Jiří Mayer, Vera Yablokova, Kurt Krejcy, Victoria Empson, Hans C Hasselbalch, Robert Kralovics, Heinz Gisslinger, PROUD-PV Study Group.
Leukemia. 2022 May;36(5):1408-1411. doi: 10.1038/s41375-022-01528-x. Epub 2022 Feb 24.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35210530/
2022

IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis

Hidde Douna, J de Mol, Jacob Amersfoort, Frank H Schaftenaar, Mate G Kiss, Bianca E Suur, Mara J Kroner, Christoph J Binder, Ilze Bot, Gijs H M Van Puijvelde, Johan Kuiper, Amanda C Foks.
Front Cardiovasc Med. 2022 Feb 2;9:781436. doi: 10.3389/fcvm.2022.781436. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35187121/
2022

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

J Ferreira da Silva, G P Oliveira, E A Arasa-Verge, C Kagiou, A Moretton, G Timelthaler, J Jiricny, J I Loizou.
Nat Commun. 2022 Feb 9;13(1):760. doi: 10.1038/s41467-022-28442-1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35140211/
2022

Rapid neutrophil mobilisation by VCAM-1+ endothelial extracellular vesicles

Naveed Akbar, Adam T Braithwaite, Emma M Corr, Graeme J Koelwyn, Coen van Solingen, Clément Cochain, Antoine-Emmanuel Saliba, Alastair Corbin, Daniela Pezzolla, Malene Møller Jørgensen, Rikke Bæk, Laurienne Edgar, Carla De Villiers, Mala Gunadasa-Rohling, Abhirup Banerjee, Daan Paget, Charlotte Lee, Eleanor Hogg, Adam Costin, Raman Dhaliwal, Errin Johnson, Thomas Krausgruber, Joey Riepsaame, Genevieve E Melling, Mayooran Shanmuganathan, Oxford Acute Myocardial Infarction Study (OxAMI), Christoph Bock, David R F Carter, Keith M Channon, Paul R Riley, Irina A Udalova, Kathryn J Moore, Daniel Anthony, Robin P Choudhury.
Cardiovasc Res. 2022 Feb 4:cvac012. doi: 10.1093/cvr/cvac012. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35134856/
2022

Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function

Tomislav Kokotović, Ewelina M Lenartowicz, Michiel Langeslag, Cosmin I Ciotu, Christopher W Fell, Angelica Scaramuzza, Michael J M Fischer, Michaela Kress, Josef M Penninger, Vanja Nagy.
FEBS J. 2022 Jun;289(12):3457-3476. doi: 10.1111/febs.16347. Epub 2022 Feb 16.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35029322/
2022

Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency

Naz Surucu Yilmaz, Sevgi Bilgic Eltan, Basak Kayaoglu, Busranur Geckin, Raul Jimenez Heredia, Asena Pinar Sefer, Ayca Kiykim, Ercan Nain, Nurhan Kasap, Omer Dogru, Ayse Deniz Yucelten, Leyla Cinel, Gulsun Karasu, Akif Yesilipek, Betul Sozeri, Goksu Gokberk Kaya, Ismail Cem Yilmaz, Ilayda Baydemir, Yagmur Aydin, Deniz Cansen Kahraman, Matthias Haimel, Kaan Boztug, Elif Karakoc-Aydiner, Ihsan Gursel, Ahmet Ozen, Safa Baris, Mayda Gursel.
J Clin Immunol. 2022 Apr;42(3):582-596. doi: 10.1007/s10875-021-01176-3. Epub 2022 Jan 14.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35028801/
2022

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

Riem Gawish, Philipp Starkl, Lisabeth Pimenov, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Shane Jf Cronin, Anna Ohradanova-Repic, Gerald Wirnsberger, Benedikt Agerer, Lukas Endler, Tümay Capraz, Jan W Perthold, Domagoj Cikes, Rubina Koglgruber, Astrid Hagelkruys, Nuria Montserrat, Ali Mirazimi, Louis Boon, Hannes Stockinger, Andreas Bergthaler, Chris Oostenbrink, Josef M Penninger, Sylvia Knapp.
Elife. 2022 Jan 13;11:e74623. doi: 10.7554/eLife.74623.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35023830/
2022

The regulatory network architecture of cardiometabolic diseases

Harald H H W Schmidt, Jörg Menche.
Nat Genet. 2022 Jan;54(1):2-3. doi: 10.1038/s41588-021-00994-w.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35022603/
2022

Oncogenic TYK2P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

Katharina Woess, Sabine Macho-Maschler, Dorette S Van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N Van Leeuwen, Roland P Kuiper, Mathias Mueller.
Haematologica. 2022 Jan 13. doi: 10.3324/haematol.2021.279848. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35021603/
2022

PD-L1 overexpression correlates with JAK2-V617F mutational burden and is associated with 9p uniparental disomy in myeloproliferative neoplasms

Jelena D Milosevic Feenstra, Roland Jäger, Fiorella Schischlik, Daniel Ivanov, Gregor Eisenwort, Elisa Rumi, Michael Schuster, Bettina Gisslinger, Sigrid Machherndl-Spandl, Peter Bettelheim, Maria-Theresa Krauth, Felix Keil, Christoph Bock, Mario Cazzola, Heinz Gisslinger, Robert Kralovics, Peter Valent.
Am J Hematol. 2022 Apr;97(4):390-400. doi: 10.1002/ajh.26461. Epub 2022 Jan 21.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35015307/
2022

Leu226Trp CACNA1A variant associated with juvenile myoclonic epilepsy with and without intellectual disability

Elham Alehabib, Tomislav Kokotović, Sakineh Ranji-Burachaloo, Abbas Tafakhori, Samira Molaei Ramshe, Zahra Esmaeilizadeh, Hossein Darvish, Abolfazl Movafagh, Vanja Nagy.
Clin Neurol Neurosurg. 2022 Feb;213:107108. doi: 10.1016/j.clineuro.2021.107108. Epub 2021 Dec 30.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34995834/
2022

Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

Lin Wang, Dominik Aschenbrenner, Zhiyang Zeng, Xiya Cao, Daniel Mayr, Meera Mehta, Melania Capitani, Neil Warner, Jie Pan, Liren Wang, Qi Li, Tao Zuo, Sarit Cohen-Kedar, Jiawei Lu, Rico Chandra Ardy, Daniel J Mulder, Dilan Dissanayake, Kaiyue Peng, Zhiheng Huang, Xiaoqin Li, Yuesheng Wang, Xiaobing Wang, Shuchao Li, Samuel Bullers, Anís N Gammage, Klaus Warnatz, Ana-Iris Schiefer, Gergely Krivan, Vera Goda, Walter H A Kahr, Mathieu Lemaire, Genomics England Research Consortium, Chien-Yi Lu, Iram Siddiqui, Michael G Surette, Daniel Kotlarz, Karin R Engelhardt, Helen R Griffin, Robert Rottapel, Hélène Decaluwe, Ronald M Laxer, Michele Proietti, Sophie Hambleton, Suzanne Elcombe, Cong-Hui Guo, Bodo Grimbacher, Iris Dotan, Siew C Ng, Spencer A Freeman, Scott B Snapper, Christoph Klein, Kaan Boztug, Ying Huang, Dali Li, Holm H Uhlig, Aleixo M Muise.
Nat Genet. 2022 Feb;54(2):213. doi: 10.1038/s41588-021-00998-6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34987219/
2022

(Not) Home alone: Antigen presenting cell - T Cell communication in barrier tissues

Teresa Neuwirth, Katja Knapp, Georg Stary.
Front Immunol. 2022 Sep 29;13:984356. doi: 10.3389/fimmu.2022.984356. eCollection 2022.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36248804/
2022

Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

Nadine Bayer, Bela Hausman, Ram Vinay Pandey, Florian Deckert, Laura-Marie Gail, Johanna Strobl, Petra Pjevac, Christoph Krall, Luisa Unterluggauer, Anna Redl, Victoria Bachmayr, Lisa Kleissl, Marion Nehr, Rasmus Kirkegaard, Athanasios Makristathis, Martin L Watzenboeck, Robert Nica, Clement Staud, Lukas Hammerl, Philipp Wohlfarth, Rupert C Ecker, Sylvia Knapp, Werner Rabitsch, David Berry, Georg Stary.
Leukemia. 2022 Nov;36(11):2705-2714. doi: 10.1038/s41375-022-01712-z. Epub 2022 Oct 12.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36224329/
2022

POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

Anna Schrempf, Sara Bernardo, Emili A Arasa Verge, Miguel A Ramirez Otero, Jordan Wilson, Dominik Kirchhofer, Gerald Timelthaler, Anna M Ambros, Atilla Kaya, Marcus Wieder, Gerhard F Ecker, Georg E Winter, Vincenzo Costanzo, Joanna I Loizou.
Cell Rep. 2022 Nov 29;41(9):111716. doi: 10.1016/j.celrep.2022.111716. Epub 2022 Nov 17.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36400033/
2022

Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms

Christian Pecquet, Nicolas Papadopoulos, Thomas Balligand, Ilyas Chachoua, Amandine Tisserand, Gaëlle Vertenoeil, Audrey Nédélec, Didier Vertommen, Anita Roy, Caroline Marty, Harini Nivarthi, Jean-Philippe Defour, Mira El-Khoury, Eva Hug, Andrea Majoros, Erica Xu, Oleh Zagrijtschuk, Tudor Emanuel Fertig, Daciana S Marta, Heinz Gisslinger, Bettina Gisslinger, Martin Schalling, Ilaria Carola Casetti, Elisa Rumi, Daniela Pietra, Chiara Cavalloni, Luca Arcaini, Mario Cazzola, Norio Komatsu, Yoshihiko Kihara, Yoshitaka Sunami, Yoko Edahiro, Marito Araki, Roman Lesyk, Veronika Buxhofer-Ausch, Sonja Heibl, Florence Pasquier, Isabelle Plo, William Vainchenker, Robert Kralovics, Stefan N Constantinescu.
Blood. 2022 Nov 10:blood.2022016846. doi: 10.1182/blood.2022016846. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36356299/
2022

Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia

Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F Wagner, Rudolf Zechner, Martina Schweiger.
J Cachexia Sarcopenia Muscle. 2022 Nov 9. doi: 10.1002/jcsm.13109. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36351437/
2022

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Alexander Hanzl, Ryan Casement, Hana Imrichova, Scott J Hughes, Eleonora Barone, Andrea Testa, Sophie Bauer, Jane Wright, Matthias Brand, Alessio Ciulli, Georg E Winter.
Nat Chem Biol. 2022 Nov 3. doi: 10.1038/s41589-022-01177-2. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36329119/
2022

Unsupervised discovery of tissue architecture in multiplexed imaging

Junbum Kim, Samir Rustam, Juan Miguel Mosquera, Scott H Randell, Renat Shaykhiev, André F Rendeiro, Olivier Elemento.
Nat Methods. 2022 Dec;19(12):1653-1661. doi: 10.1038/s41592-022-01657-2. Epub 2022 Oct 31.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36316562/
2022

Leptin increases hepatic triglyceride export via a vagal mechanism in humans

Matthäus Metz, Marianna Beghini, Peter Wolf, Lorenz Pfleger, Martina Hackl, Magdalena Bastian, Angelika Freudenthaler, Jürgen Harreiter, Maximilian Zeyda, Sabina Baumgartner-Parzer, Rodrig Marculescu, Nara Marella, J Thomas Hannich, Georg Györi, Gabriela Berlakovich, Michael Roden, Michael Krebs, Robert Risti, Aivar Lõokene, Michael Trauner, Alexandra Kautzky-Willer, Martin Krššák, Herbert Stangl, Clemens Fürnsinn, Thomas Scherer.
Cell Metab. 2022 Nov 1;34(11):1719-1731.e5. doi: 10.1016/j.cmet.2022.09.020. Epub 2022 Oct 10.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36220067/
2022

Tick feeding modulates the human skin immune landscape to facilitate tick-borne pathogen transmission

Johanna Strobl, Verena Mündler, Sophie Müller, Anna Gindl, Sara Berent, Anna-Margarita Schötta, Lisa Kleissl, Clement Staud, Anna Redl, Luisa Unterluggauer, Ana E Aguilar González, Sophie T Weninger, Denise Atzmüller, Romana Klasinc, Gerold Stanek, Mateusz Markowicz, Hannes Stockinger, Georg Stary.
J Clin Invest. 2022 Nov 1;132(21):e161188. doi: 10.1172/JCI161188.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36166299/
2022

Identification of MHC-I-Presented Porcine Respiratory and Reproductive Syndrome Virus (PRRSV) Peptides Reveals Immunogenic Epitopes within Several Non-Structural Proteins Recognized by CD8+ T Cells

Marlene Mötz, Melissa R Stas, Sabine E Hammer, Tereza Duckova, Frederic Fontaine, Alexandra Kiesler, Kerstin Seitz, Andrea Ladinig, André C Müller, Christiane Riedel, Armin Saalmüller, Till Rümenapf.
Viruses. 2022 Aug 26;14(9):1891. doi: 10.3390/v14091891.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36146698/
2022

TMBIM5 is the Ca2+ /H+ antiporter of mammalian mitochondria

Shane Austin, Ronald Mekis, Sami E M Mohammed, Mariafrancesca Scalise, Wen-An Wang, Michele Galluccio, Christina Pfeiffer, Tamara Borovec, Katja Parapatics, Dijana Vitko, Nora Dinhopl, Nicolas Demaurex, Keiryn L Bennett, Cesare Indiveri, Karin Nowikovsky.
EMBO Rep. 2022 Nov 2:e54978. doi: 10.15252/embr.202254978. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36321428/
2022

Author Correction: Unsupervised discovery of tissue architecture in multiplexed imaging

Junbum Kim, Samir Rustam, Juan Miguel Mosquera, Scott H Randell, Renat Shaykhiev, André F Rendeiro, Olivier Elemento.
Nat Methods. 2022 Dec;19(12):1662. doi: 10.1038/s41592-022-01717-7.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36414761/
2022

Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.

Vincent Geldhof, Laura P M H de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet.
Nat Commun. 2022 Sep 20;13(1):5511. doi: 10.1038/s41467-022-33052-y.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36127427/
2022

Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity

Marcello Polesel, Alvaro Ingles-Prieto, Eirini Christodoulaki, Evandro Ferrada, Cédric Doucerain, Patrick Altermatt, Michelle Knecht, Michael Kuhn, Anna-Lena Steck, Maria Wilhelm, Vania Manolova.
Biometals. 2022 Dec 1. doi: 10.1007/s10534-022-00474-6. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36454509/