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Year
Paper
2014
ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, Loizou JI. DNA Repair (Amst). 2014 Sep 24. pii: S1568-7864(14)00223-7. doi: 10.1016/j.dnarep.2014.09.001. [Epub ahead of print] PMID: 25262557.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25262557
2014
Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, Bressac-de Paillerets B, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Grgurević N, Gut I, Heijmans BT, Hermouet S, Houwing-Duistermaat J, Iacobucci I, Ilaš J, Kandimalla R, Krauss-Etschmann S, Lasko P, Lehmann S, Lindroth A, Majdič G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Nickel D, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Potočnik U, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidaković M, Widschwendter M. Relationship between genome and epigenome--challenges and requirements for future research. BMC Genomics. 2014 Jun 18;15:487. doi: 10.1186/1471-2164-15-487.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24942464
2014
Assenov Y, Müller F, Lutsik P, Walter J, Lengauer T, Bock C. Comprehensive analysis of DNA methylation data with RnBeads. Nature Methods 11, 1138–1140 (2014) doi:10.1038/nmeth.3115.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25262207
2014
Ban SA, Salzer E, Eibl MM, Linder A, Geier CB, Santos-Valente E, Garncarz W, Lion T, Ott R, Seelbach C, Boztug K, Wolf HM. Combined Immunodeficiency Evolving into Predominant CD4+ Lymphopenia Caused by Somatic Chimerism in JAK3. J Clin Immunol. 2014 Sep 10. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25205547
2014
Barlow DP, Bartolomei MS. Genomic imprinting in mammals. Cold Spring Harb Perspect Biol. 2014 Feb 1;6(2). pii: a018382. doi: 10.1101/cshperspect.a018382.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24492710
2014
Bassett AR, Akhtar A, Barlow DP, Bird AP, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith AC, Gingeras TR, Haerty W, Higgs DR, Miska EA, Ponting CP. Considerations when investigating lncRNA function in vivo. Elife. 2014 Aug 14;3:e03058. doi: 10.7554/eLife.03058.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25124674
2014
Becker D, Lutsik P, Ebert P, Bock C, Lengauer T, Walter J. BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W501-7. doi: 10.1093/nar/gku457. Epub 2014 May 29.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24875479
2014
Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras IZ, Menzl I, Putz EM, Hoermann G, Schuster C, Fajmann S, Leitner E, Kubicek S, Moriggl R, Gouilleux F, Sexl V. PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis. Leukemia. 2014 Mar;28(3):629-41. doi: 10.1038/leu.2013.351. Epub 2013 Nov 22.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24263804
2014
Beşer OF, Conde CD, Kutlu T, Cokuğraş FC, Boztuğ K, Erkan T. Inflammatory Bowel Disease With Lethal Disease Course Caused By A Nonsense Mutation in BIRC4 Encoding X-linked Inhibitor of Apoptosis Protein (XIAP). J Pediatr Gastroenterol Nutr. 2014 Jul 11. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25023582
2014
Bock C. Synergy and competition between cancer genome sequencing and epigenome mapping projects. Genome Med. 2014 May 30;6(5):41. doi: 10.1186/gm557. eCollection 2014.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25031623
2014
Bonafé L, Liang J, Gorna MW, Zhang Q, Ha-Vinh R, Campos-Xavier AB, Unger S, Beckmann JS, Le Béchec A, Stevenson B, Giedion A, Liu X, Superti-Furga G, Wang W, Spahr A, Superti-Furga A. MMP13 mutations are the cause of recessive metaphyseal dysplasia, Spahr type. Am J Med Genet A. 2014 May;164A(5):1175-9. doi: 10.1002/ajmg.a.36431. Epub 2014 Mar 19.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24648384
2014
Boucheron N, Tschismarov R, Goeschl L, A Moser M, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W. Corrigendum: CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. Nat Immunol. 2014 Aug 19;15(9):894.doi:10.1038/ni0914-894e.
Abstract: http://www.nature.com/ni/journal/v15/n9/full/ni0914-894e.html
2014
Boucheron N, Tschismarov R, Goeschl L, Moser M, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Haust L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W. CD4 T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. Nat Immunol. 2014 May;15(5):439-48. doi: 10.1038/ni.2864. Epub 2014 Mar 30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24681565
2014
Boztug K, Järvinen PM, Salzer E, Racek T, Mönch S, Garncarz W, Gertz EM, Schäffer AA, Antonopoulos A, Haslam SM, Schieck L, Puchałka J, Diestelhorst J, Appaswamy G, Lescoeur B, Giambruno R, Bigenzahn JW, Elling U, Pfeifer D, Conde CD, Albert MH, Welte K, Brandes G, Sherkat R, van der Werff Ten Bosch J, Rezaei N, Etzioni A, Bellanné-Chantelot C, Superti-Furga G, Penninger JM, Bennett KL, von Blume J, Dell A, Donadieu J, Klein C. JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia. Nat Genet. 2014 Sep;46(9):1021-7. doi: 10.1038/ng.3069. Epub 2014 Aug 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25129144
2014
Braun CJ, Boztug K, Paruzynski A, Witzel M, Schwarzer A, Rothe M, Modlich U, Beier R, Göhring G, Steinemann D, Fronza R, Ball CR, Haemmerle R, Naundorf S, Kühlcke K, Rose M, Fraser C, Mathias L, Ferrari R, Abboud MR, Al-Herz W, Kondratenko I, Maródi L, Glimm H, Schlegelberger B, Schambach A, Albert MH, Schmidt M, von Kalle C, Klein C. Gene therapy for wiskott-Aldrich syndrome--long-term efficacy and genotoxicity. Sci Transl Med. 2014 Mar 12;6(227):227ra33. doi: 10.1126/scitranslmed.3007280.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24622513
2014
Broséus J, Lippert E, Harutyunyan AS, Jeromin S, Zipperer E, Florensa L, Milosevic JD, Haferlach T, Germing U, Luño E, Schnittger S, Kralovics R, Girodon F. Low rate of calreticulin mutations in refractory anaemia with ring sideroblasts and marked thrombocytosis. Leukemia. 2014 Jun;28(6):1374-6. doi: 10.1038/leu.2014.49. Epub 2014 Jan 30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24476766
2014
Buxhofer-Ausch V, Olcaydu D, Gisslinger B, Schalling M, Frantal S, Thiele J, Müllauer L, Kvasnicka HM, Watzke H, Kralovics R, Gisslinger H. Decanucleotide insertion polymorphism of F7 significantly influences the risk of thrombosis in patients with essential thrombocythemia. Eur J Haematol. 2014 Aug;93(2):103-11. doi: 10.1111/ejh.12307. Epub 2014 Apr 23.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24617727
2014
Cazzola M, Kralovics R. From Janus kinase 2 to calreticulin: the clinically relevant genomic landscape of myeloproliferative neoplasms. Blood. 2014 Jun 12;123(24):3714-9. doi: 10.1182/blood-2014-03-530865. Epub 2014 Apr 30.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24786775
2014
Cazzola M, Kralovics R. JAK inhibitor in CALR-mutant myelofibrosis. N Engl J Med. 2014 Mar 20;370(12):1169. doi: 10.1056/NEJMc1400499. Comment.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24645955
2014
Choudhary A, Hu He K, Mertins P, Udeshi ND, Dančík V, Fomina-Yadlin D, Kubicek S, Clemons PA, Schreiber SL, Carr SA, Wagner BK. Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming. PLoS One. 2014 Apr 23;9(4):e95194. doi: 10.1371/journal.pone.0095194.
Abstract: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0095194
2014
Colinge J, César-Razquin A, Huber K, Breitwieser FP, Májek P, Superti-Furga G. Building and exploring an integrated human kinase network: global organization and medical entry points. J Proteomics. 2014 Jul 31;107:113-27. doi: 10.1016/j.jprot.2014.03.028. Epub 2014 Apr 3.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24704859
2014
DNA replication stress: Causes, resolution and disease.Mazouzi A, Velimezi G, Loizou JI.Exp Cell Res. 2014 Sep 30. pii: S0014-4827(14)00435-2. doi: 10.1016/j.yexcr.2014.09.030. [Epub ahead of print] Review.PMID: 25281304.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25281304
2014
Dancík V, Carrel H, Bodycombe NE, Seiler KP, Fomina-Yadlin D, Kubicek ST, Hartwell K, Shamji AF, Wagner BK, Clemons PA. Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses. J Biomol Screen. 2014 Jan 24;19(5):771-781. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24464433
2014
Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F. Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a. Cell Rep. 2014 Aug 7;8(3):743-53. doi: 10.1016/j.celrep.2014.06.048. Epub 2014 Jul 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25066127
2014
Eberle CA, Zayas M, Stukalov A, Pichlmair A, Alvisi G, Müller AC, Bennett KL, Bartenschlager R, Superti-Furga G. The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production. Virology. 2014 Aug;462-463:34-41. doi: 10.1016/j.virol.2014.05.016. Epub 2014 Jun 14.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25092459
2014
Ghafari M, Whittle N, Miklósi AG, Kotlowski C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G. Erratum to: Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice. Brain Struct Funct. 2014 Jun 26. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24965486
2014
Ghafari M, Whittle N, Miklósi AG, Kotlowsky C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G. Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice. Brain Struct Funct. 2014 May 8. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24807818
2014
Giansanti P, Preisinger C, Huber KV, Gridling M, Superti-Furga G, Bennett KL, Heck AJ. Evaluating the promiscuous nature of tyrosine kinase inhibitors assessed in A431 epidermoid carcinoma cells by both chemical- and phosphoproteomics. ACS Chem Biol. 2014 Jul 18;9(7):1490-8. doi: 10.1021/cb500116c. Epub 2014 May 14.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24804581
2014
Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. Atheroprotective immunization with malondialdehyde modified LDL is hapten-specific and dependent on advanced MDA-adducts: Implications for development of an atheroprotective vaccine. J Lipid Res. 2014 Oct;55(10):2137-55. doi: 10.1194/jlr.M053256. Epub 2014 Aug 20.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25143462
2014
Gridling M, Ficarro S, Breitwieser FP, Song L, Parapatics K, Colinge J, Haura EB, Marto J, Superti-Furga G, Bennett KL, Rix U. Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics. Mol Cancer Ther. 2014 Sep 4. pii: molcanther.0152.2014. [Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25189542
2014
Herzog VA, Lempradl A, Trupke J, Okulski H, Altmutter C, Ruge F, Boidol B, Kubicek S, Schmauss G, Aumayr K, Ruf M, Pospisilik A, Dimond A, Senergin HB, Vargas ML, Simon JA, Ringrose L. A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element. Nat Genet. 2014 Sep;46(9):973-81. doi: 10.1038/ng.3058. Epub 2014 Aug 10.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25108384
2014
Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24695225
2014
Huber ML, Sacco R, Parapatics K, Skucha A, Khamina K, Müller AC, Rudashevskaya EL, Bennett KL. abFASP-MS: Affinity-Based Filter-Aided Sample Preparation Mass Spectrometry for Quantitative Analysis of Chemically Labeled Protein Complexes. J Proteome Res. 2014 Feb 7;13(2):1147-55. doi: 10.1021/pr4009892. Epub 2014 Jan 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24400740
2014
Jae LT, Raaben M, Herbert AS, Kuehne AI, Wirchnianski AS, Soh TK, Stubbs SH, Janssen H, Damme M, Saftig P, Whelan SP, Dye JM, Brummelkamp TR. Virus entry. Lassa virus entry requires a trigger-induced receptor switch. Science. 2014 Jun 27;344(6191):1506-10. doi: 10.1126/science.1252480.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24970085
2014
Jais A, Einwallner E, Sharif O, Gossens K, Lu TT, Soyal SM, Medgyesi D, Neureiter D, Paier-Pourani J, Dalgaard K, Duvigneau JC, Lindroos-Christensen J, Zapf TC, Amann S, Saluzzo S, Jantscher F, Stiedl P, Todoric J, Martins R, Oberkofler H, Müller S, Hauser-Kronberger C, Kenner L, Casanova E, Sutterlüty-Fall H, Bilban M, Miller K, Kozlov AV, Krempler F, Knapp S, Lumeng CN, Patsch W, Wagner O, Pospisilik JA, Esterbauer H. Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell. 2014 Jul 3;158(1):25-40. doi: 10.1016/j.cell.2014.04.043.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24995976
2014
Jäger R, Harutyunyan AS, Rumi E, Pietra D, Berg T, Olcaydu D, Houlston RS, Cazzola M, Kralovics R. Common germline variation at the TERT locus contributes to familial clustering of myeloproliferative neoplasms. Am J Hematol. 2014 Sep 5. doi: 10.1002/ajh.23842.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25196853
2014
Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, Superti-Furga G, Pichlmair A, Weber F. Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-Box Protein FBXO3 To Degrade Subunit p62 of General Transcription Factor TFIIH. J Virol. 2014 Mar;88(6):3464-73. doi: 10.1128/JVI.02914-13. Epub 2014 Jan 8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24403578
2014
Karonitsch T, Dalwigk K, Holinka J, Niederreiter B, Steiner CW, Bilban M, Wanivenhaus A, Windhager R, Smolen JS, Kiener HP, Superti-Furga G.1. A dual role of MTOR in the rheumatoid mesenchymal tissue response to inflammation. Ann Rheum Dis. 2014 Mar 1;73 Suppl 1:A3-4. doi: 10.1136/annrheumdis-2013-205124.8.
Abstract: http://ard.bmj.com/content/73/Suppl_1/A3.3
2014
Köffel R, Meshcheryakova A, Warszawska J, Hennig A, Wagner K, Jörgl A, Gubi D, Moser D, Hladik A, Hoffmann U, Fischer MB, van den Berg W, Koenders M, Scheinecker C, Gesslbauer B, Knapp S, Strobl H. Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation. Blood. 2014 Sep 11. pii: blood-2014-07-588178.[Epub ahead of print]
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25214442
2014
Liehl P, Zuzarte-Luís V, Chan J, Zillinger T, Baptista F, Carapau D, Konert M, Hanson KK, Carret C, Lassnig C, Müller M, Kalinke U, Saeed M, Chora AF, Golenbock DT, Strobl B, Prudêncio M, Coelho LP, Kappe SH, Superti-Furga G, Pichlmair A, Vigário AM, Rice CM, Fitzgerald KA, Barchet W, Mota MM. Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nat Med. 2014 Jan;20(1):47-53. doi: 10.1038/nm.3424. Epub 2013 Dec 22.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24362933
2014
Lundberg P, Karow A, Nienhold R, Looser R, Hao-Shen H, Nissen I, Girsberger S, Lehmann T, Passweg J, Stern M, Beisel C, Kralovics R, Skoda RC. Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood. 2014 Apr 3;123(14):2220-8. doi: 10.1182/blood-2013-11-537167. Epub 2014 Jan 29.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24478400
2014
Mair B, Kubicek S, Nijman SM. Exploiting epigenetic vulnerabilities for cancer therapeutics. Trends Pharmacol Sci. 2014 Mar;35(3):136-145. doi: 10.1016/j.tips.2014.01.001. Epub 2014 Feb 12. Review.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24529765
2014
Marty C, Saint-Martin C, Pecquet C, Grosjean S, Saliba J, Mouton C, Leroy E, Harutyunyan AS, Abgrall JF, Favier R, Toussaint A, Solary E, Kralovics R, Constantinescu SN, Najman A, Vainchenker W, Plo I, Bellanné-Chantelot C. Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors. Blood. 2014 Feb 27;123(9):1372-83. doi: 10.1182/blood-2013-05-504555. Epub 2014 Jan 7.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24398328
2014
Maurer M, Müller AC, Parapatics K, Pickl WF, Wagner C, Rudashevskaya EL, Breitwieser FP, Colinge J, Garg K, Griss J, Bennett KL, Wagner SN. Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma. J Proteome Res. 2014 Jun 6;13(6):2830-45. doi: 10.1021/pr401270y. Epub 2014 May 6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24803318
2014
Muellner MK, Duernberger G, Ganglberger F, Kerzendorfer C, Uras IZ, Schoenegger A, Bagienski K, Colinge J, Nijman SM. TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens. BMC Bioinformatics. 2014 Apr 8;15:98. doi: 10.1186/1471-2105-15-98.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24712852
2014
Rumi E, Harutyunyan AS, Pietra D, Milosevic JD, Casetti IC, Bellini M, Them NC, Cavalloni C, Ferretti VV, Milanesi C, Berg T, Sant'antonio E, Boveri E, Pascutto C, Astori C, Kralovics R, Cazzola M. CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis. Blood. 2014 Apr 10;123(15):2416-9. doi: 10.1182/blood-2014-01-550434. Epub 2014 Feb 19.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24553179
2014
Salzer E, Kansu A, Sic H, Májek P, Ikincioğullari A, Dogu FE, Prengemann NK, Santos-Valente E, Pickl WF, Bilic I, Ban SA, Kuloğlu Z, Demir AM, Ensari A, Colinge J, Rizzi M, Eibel H, Boztug K. Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency. J Allergy Clin Immunol. 2014 Jun;133(6):1651-9.e12. doi: 10.1016/j.jaci.2014.02.034. Epub 2014 Apr 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24746753
2014
Salzer E, Kansu A, Sic H, Májek P, Ikincioğullari A, Dogu FE, Prengemann NK, Santos-Valente E, Pickl WF, Bilic I, Ban SA, Kuloğlu Z, Demir AM, Ensari A, Colinge J, Rizzi M, Eibel H, Boztug K. Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency. J Allergy Clin Immunol. 2014 Jun;133(6):1651-9.e12. doi: 10.1016/j.jaci.2014.02.034. Epub 2014 Apr 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24746753
2014
Sanchez-Mut JV, Aso E, Heyn H, Matsuda T, Bock C, Ferrer I, Esteller M. Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease. Hippocampus. 2014 Apr;24(4):363-8. doi: 10.1002/hipo.22245. Epub 2014 Jan 28.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24436131
2014
Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett AL, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein MM, Symer DE, Aderem A, Bergthaler A. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nature Immunology. 2014 Nov 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25419628
2014
Schuh C, Wimmer I, Hametner S, Haider L, Van Dam AM, Liblau RS, Smith KJ, Probert L, Binder CJ, Bauer J, Bradl M, Mahad D, Lassmann H. Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models. Acta Neuropathol. 2014 Aug;128(2):247-66. doi: 10.1007/s00401-014-1263-5. Epub 2014 Mar 13.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24622774
2014
Seidel MG, Duerr C, Woutsas S, Schwerin-Nagel A, Sadeghi K, Neesen J, Uhrig S, Santos-Valente E, Pickl WF, Schwinger W, Urban C, Boztug K*, Förster-Waldl E*.A novel immunodeficiency syndrome associated with partial trisomy 19p13. J Med Genet. 2014 Apr;51(4):254-63. doi: 10.1136/jmedgenet-2013-102122. Epub 2014 Jan 15. (*equal contributing authors)
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24431329
2014
Serwas NK, Cagdas D, Ban SA, Bienemann K, Salzer E, Tezcan I, Borkhardt A, Sanal O, Boztug K. Identification of ITK deficiency as a novel genetic cause of idiopathic CD4+ T-cell lymphopenia. Blood. 2014 Jul 24;124(4):655-7. doi: 10.1182/blood-2014-03-564930.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25061172
2014
Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M, Knapp S. The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia. PLoS Pathog. 2014 Jun 12;10(6):e1004167. doi: 10.1371/journal.ppat.1004167. eCollection 2014.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24945405
2014
Snijder B, Kandasamy RK, Superti-Furga G. Toward effective sharing of high-dimensional immunology data. Nat Biotechnol. 2014 Aug;32(8):755-9. doi: 10.1038/nbt.2974.
Abstract: http://www.nature.com/nbt/journal/v32/n8/full/nbt.2974.html
2014
Szilagyi K, Meijer AB, Neele AE, Verkuijlen P, Leitges M, Dabernat S, Förster-Waldl E, Boztug K, Belot A, Kuijpers TW, Kraal G, de Winther MP, van den Berg TK. PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages. Cardiovasc Res. 2014 Sep 24. pii: cvu213.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25253077
2014
Tsiantoulas D, Diehl CJ, Witztum JL, Binder CJ. B cells and humoral immunity in atherosclerosis. Circ Res. 2014 May 23;114(11):1743-56. doi: 10.1161/CIRCRESAHA.113.301145.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24855199
2014
Vladimer GI, Górna MW, Superti-Furga G. IFITs: Emerging Roles as Key Anti-Viral Proteins. Front Immunol. 2014 Mar 10;5:94. doi: 10.3389/fimmu.2014.00094. eCollection 2014.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24653722
2014
Winter GE, Radic B, Mayor-Ruiz C, Blomen VA, Trefzer C, Kandasamy RK, Huber KV, Gridling M, Chen D, Klampfl T, Kralovics R, Kubicek S, Fernandez-Capetillo O, Brummelkamp TR, Superti-Furga G. The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity. Nat Chem Biol. 2014 Sep;10(9):768-73. doi: 10.1038/nchembio.1590. Epub 2014 Jul 27.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25064833
2014
Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu SW, Perlot T, Järvinen P, Dürnberger G, Kozieradzki I, Sarao R, De Martino A, Boztug K, Mechtler K, Kuchler K, Klein C, Elling U, Penninger JM. Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. Nat Genet. 2014 Sep;46(9):1028-33. doi: 10.1038/ng.3070. Epub 2014 Aug 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/25129145
2014
Wolf D, Jehle F, Michel NA, Bukosza N, Rivera J, Chen YC, Hoppe N, Dufner B, Ortiz Rodriguez A, Colberg C, Nieto L, Rupprecht B, Wiedemann A, Schulte L, Peikert A, Bassler N, Lozhkin A, Hergeth SP, Stachon P, Hilgendorf I, Willecke F, von zur Muhlen C, von Elverfeld D, Binder CJ, Aichele P, Varo N, Febbraio M, Libby P, Bode C, Peter K and Zirlik A. Co-inhibitory suppression of T cell activation by CD40 protects from obesity and adipose tissue inflammation in mice. Circulation. Circulation. 2014 Jun 10;129(23):2414-25. doi: 10.1161/CIRCULATIONAHA.113.008055. Epub 2014 Mar 24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/24664276