Publications
Year
Paper
2009
Aebersold R, Auffray C, ..., Superti-Furga G, et al. Report on EU-USA workshop: how systems biology can advance cancer research. Mol Oncol, 2009 Feb;3(1):9-17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19383362
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19383362
2009
Amir S, Binder CJ. Experimental immunotherapeutic approaches for atherosclerosis. Clin Immunol, Epub 2009 Aug 8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19666239
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19666239
2009
Barlow DP. Non-coding RNAs: A higher level of genome encoded information. RNA Biol, 2009 Apr;6(2):93. Editorial.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19885992
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19885992
2009
Bochkov VN, Oskolkova OV, Birukov KG, Levonen AL, Binder CJ, Stöckl J. Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal, Epub 2009 Aug 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19686040
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19686040
2009
Brehme M, Hantschel O, Colinge J, Kaupe I, Planyavsky M, Köcher T, Mechtler K, Bennett KL, Superti-Furga G. Charting the molecular network of the drug target Bcr-Abl. Proc Natl Acad Sci USA, 2009 May 5;106(18): 7414-9. Epub 2009 Apr 20.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19380743
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19380743
2009
Brehme M. Intercell – accelerating innovation. N Biotechnol, 2009 Apr;25(4):181-4. Epub 2009 Feb 21.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19429533
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19429533
2009
Buxhofer-Ausch V, Gisslinger H, Berg T, Gisslinger B, Kralovics R. Acquired resistance to interferon alpha therapy associated with homozygous MPL-W515L mutation and chromosome 20q deletion in primary myelofifibrosis. Eur J Haematol, 2009 Feb;82(2):161-3.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19018861
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19018861
2009
Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H, Planyavsky M, Bilban M, Colinge J, Bennett KL, Superti-Furga G. An orthogonal proteomic-genomic screen identififies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol, 2009 Mar;10(3):266-72. Epub 2009 Jan 21.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19158679
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19158679
2009
Chou MY, Fogelstrand L, Hartvigsen K, Hansen LF, Woelkers D, Shaw PX, Choi J, Perkmann T, Bäckhed F, Miller YI, Hörkkö S, Corr M, Witztum JL, Binder CJ. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest, 2009 May;119(5):1335-49. Epub 2009 Apr 13.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19363291
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19363291
2009
Fernbach NV, Planyavsky M, Müller A, Breitwieser FP, Colinge J, Rix U, Bennett KL. Acid elution and one-dimensional shotgun analysis on an orbitrap mass spectrometer – an application to drug affifinity chromatography. J 2009 Oct;8(10):4753-65.Proteome Res,.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19653696
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19653696
2009
Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S. Peptide Bbeta (15-42) preserves endothelial barrier function in shock. PLoS ONE, 2009;4(4): e5391. Epub 2009 Apr 29.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19401765
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19401765
2009
Habjan M, Pichlmair A, Elliott RM, Overby AK, Glatter T, Gstaiger M, Superti-Furga G, Unger H, Weber F. NSs protein of rift valley fever virus induces the specific degradation of the double stranded RNA-dependent protein kinase. J Virol, 2009 May;83(9):4365-75. Epub 2009 Feb 11.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19211744
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19211744
2009
Hartvigsen K, Chou MY, Hansen LF, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. The role of innate immunity in atherogenesis. J Lipid Res, 2009 Apr;50 Suppl:S388-93.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19106070
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19106070
2009
Hoshida Y, Nijman SM, Kobayashi M, Chan JA, Brunet JP, Chiang DY, Villanueva A, Newell P, Ikeda K, Hashimoto M, Watanabe G, Gabriel S, Friedman SL, Kumada H, Llovet JM, Golub TR. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res, 2009 Sep 15; 69(18):7385-92. Epub 2009 Sep 1.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19723656
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19723656
2009
Karayel E, Bürckstümmer T, Weitzer S, Martinez J, Superti-Furga G. The TLR independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature. Eur J Immunol, 2009 Jul;39(7):1929-36.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19551900
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19551900
2009
Kelly JA, Griffifin ME, Fava RA, Wood SG, Bessette KA, Miller ER, Huber SA, Binder CJ, Witztum JL, Morganelli PM. Inhibition of arterial lesion progression in CD16-defificient mice: evidence for altered immunity and the role of IL-10. Cardiovasc Res, Epub 2009 Sep 19.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19720605
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19720605
2009
Koerner MV, Pauler FM, Huang R, Barlow DP. The function of non-coding RNAs in genomic imprinting. Development, 2009 Jun;136(11): 1771-83.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19429783
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19429783
2009
Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia. J Immunol, 2009 Aug;183(3): 2027-36. Epub 2009 Jul 13.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19596984
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19596984
2009
Latos PA, Barlow DP. Regulation of imprinted expression by macro non-coding RNAs. RNA Biol, 2009 Apr;6(2):100-6. Epub 2009 Apr 14.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19229135
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19229135
2009
Latos PA, Stricker SH, Steenpass L, Pauler FM, Huang R, Senergin BH, Regha K, Koerner MV, Warczok KE, Unger C, Barlow DP. An in vitro ES cell imprinting model shows that imprinted expression of the Igf2r gene arises from an allelespecifific expression bias. Development, 2009 Feb;136(3):437-48 (Featured article).
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19141673
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19141673
2009
Lutz HU, Binder CJ, Kaveri S. Naturally occurring auto-antibodies in homeostasis and disease. Trends Immunol, 2009 Jan;30(1):43-51.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19058756
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19058756
2009
Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S. B15-42 protects against acid-induced acute lung injury and secondary Pseudomonas pneumonia in vivo. Am J Respir Crit Care Med, 2009 Dec;180(12):1208-17. Epub 2009 Sep 17.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19762562
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19762562
2009
Moser C, Pohl G, Haslinger I, Knapp S, Rowczenio D, Russel T, Lachmann HJ, Lang U, Kovarik J. Successful treatment of familial Mediterranean fever with Anakinra and outcome after renal transplantation. Nephrol Dial Transplant, 2009 Feb;24(2):676-8.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19033248
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19033248
2009
Olcaydu D, Harutyunyan A, Jäger R, Berg T, Gisslinger B, Pabinger I, Gisslinger H, Kralovics R. A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms. Nature Genetics, 2009 41(4):450-4. Epub 2009 Mar 15.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19287385
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19287385
2009
Olcaydu D, Skoda RC, Looser R, Li S, Cazzola M, Pietra D, Passamonti F, Lippert E, Carillo S, Girodon F, Vannucchi A, Reading NS, Prchal JT Ay C, Pabinger I, Gisslinger H, Kralovics R. The GGCC haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation positive polycythemia vera. Leukemia, 2009 Oct;23(10):1924-6. Epub 2009 May 14.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19440215
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19440215
2009
Pauler FM, Sloane MA, Huang R, Regha K, Koerner MV, Tamir I, Sommer A, Aszodi A, Jenuwein T, Barlow DP. H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res, 2009 Feb;19(2):221-33.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19047520
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19047520
2009
Perne A, Muellner MK, Steinrueck M, Craig- Mueller N, Mayerhofer J, Schwarzinger I, Sloane M, Uras IZ, Hoermann G, Nijman SM, Mayerhofer M. Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. PLoS One, 2009 Dec 16; 4(12):e8292.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20016840
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/20016840
2009
Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G, Reis e Sousa C. Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol, 2009 Oct;83(20):10761-9. Epub 2009 Aug 5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19656871
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19656871
2009
Remsing Rix LL, Rix U, Colinge J, Hantschel O, Bennett KL, Stranzl T, Müller A, Baumgartner C, Valent P, Augustin M, Till JH, Superti-Furga G. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells. Leukemia, 2009 Mar;23(3):477-85.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19039322
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19039322
2009
Rix U, Remsing Rix LL, Terker AS, Fernbach NV, Hantschel O, Planyavsky M, Breitwieser FP, Herrmann H, Colinge J, Bennett KL, Augustin M, Till JH, Heinrich MC, Valent P, Superti-Furga G. A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profifiling and chemical proteomics in chronic myeloid leukemia cells. Leukemia, Epub 2009 Nov 5.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19890374
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19890374
2009
Rix U, Superti-Furga G. Target profiling of small molecules by chemical proteomics. Nat Chem Biol, 2009 Sep;5(9):616-24.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19690537
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19690537
2009
Schaub FX, Jäger R, Looser R, Hao-Shen H, Hermouet S, Girodon F, Tichelli A, Gisslinger H, Kralovics R, Skoda RC. Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F. Blood, 2009 Feb;113(9):2022-7.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19047681
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19047681
2009
Schwartz-Albiez R, Monteiro RC, Rodriguez M, Binder CJ, Shoenfeld Y. Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation. Clin Exp Immunol, 2009 Dec;158 Suppl 1:43-50.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19883423
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19883423
2009
Sillaber C, Herrmann H, Bennett K, Rix U, Baumgartner C, Böhm A, Herndlhofer S, Tschachler E, Superti-Furga G, Jäger U, Valent P. Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily. Eur J Clin Invest, 2009 Dec;39(12): 1098-109.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19744184
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19744184
2009
Superti-Furga G. A biomedical adventurers’ guide to navigating between careers in academia and industry. Nat Rev Mol Cell Biol, 2009 Dec;10(12):884-7.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19859061
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19859061
2009
Winger JA, Hantschel O, Superti-Furga G, Kuriyan J. The structure of the leukemia drug imatinib bound to human quinine reductase 2 (NQO2). BMC Struct Biol, 2009 Feb;9:7.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19236722
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19236722
2009
von Schlieffen E, Oskolkova OV, Schabbauer G, Gruber F, Blüml S, Genest M, Kadl A, Marsik C, Knapp S, Chow J, Leitinger N, Binder BR, Bochkov VN. Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids. Arterioscler Thromb Vasc Biol, 2009 Mar; 29(3):356-62. Epub 2008 Dec 26.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19112167
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/19112167