Publications
2020
Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets.
Marquina-Sanchez B,
Fortelny N,
Farlik M,
Vieira A,
Collombat P,
Bock C,
Kubicek S.
Genome Biol. 2020 May 6;21(1):106. doi: 10.1186/s13059-020-02006-2.
2020
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.
Maurer B,
Nivarthi H,
Wingelhofer B,
Pham HTT,
Schlederer M,
Suske T,
Grausenburger R,
Schiefer AI,
Prchal-Murphy M,
Chen D,
Winkler S,
Merkel O,
Kornauth C,
Hofbauer M,
Hochgatterer B,
Hoermann G,
Hoelbl-Kovacic A,
Prochazkova J,
Lobello C,
Cumaraswamy AA,
Latzka J,
Kitzwögerer M,
Chott A,
Janikova A,
Pospíšilova Š,
Loizou JI,
Kubicek S,
Valent P,
Kolbe T,
Grebien F,
Kenner L,
Gunning PT,
Kralovics R,
Herling M,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986.
2020
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs.
Girardi E,
César-Razquin A,
Lindinger S,
Papakostas K,
Konecka J,
Hemmerich J,
Kickinger S,
Kartnig F,
Gürtl B,
Klavins K,
Sedlyarov V,
Ingles-Prieto A,
Fiume G,
Koren A,
Lardeau CH,
Kumaran Kandasamy R,
Kubicek S,
Ecker GF,
Superti-Furga G.
Nat Chem Biol. 2020 Apr;16(4):469-478. doi: 10.1038/s41589-020-0483-3. Epub 2020 Mar 9.
2019
Mapping the perturbome network of cellular perturbations.
Caldera M,
Müller F,
Kaltenbrunner I,
Licciardello MP,
Lardeau CH,
Kubicek S,
Menche J.
Nat Commun. 2019 Nov 13;10(1):5140. doi: 10.1038/s41467-019-13058-9.
2019
A Domino 10-Step Total Synthesis of FR252921 and Its Analogues, Complex Macrocyclic Immunosuppressants.
Chen Y,
Coussanes G,
Souris C,
Aillard P,
Kaldre D,
Runggatscher K,
Kubicek S,
Di Mauro G,
Maryasin B,
Maulide N.
J Am Chem Soc. 2019 Sep 4;141(35):13772-13777. doi: 10.1021/jacs.9b07185.
2019
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.
Kosack L,
Wingelhofer B,
Popa A,
Orlova A,
Agerer B,
Vilagos B,
Majek P,Parapatics K,
Lercher A,
Ringler A,
Klughammer J,
Smyth M,
Khamina K,
Baazim H,de Araujo ED,
Rosa DA,
Park J,
Tin G,
Ahmar S,
Gunning PT,
Bock C,
Siddle HV,Woods GM,
Kubicek S,
Murchison EP,
Bennett KL,
Moriggl R,
Bergthaler A.
Cancer Cell. 2019Jan 14;35(1):125-139.e9. doi: 10.1016/j.ccell.2018.11.018.
2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Sdelci S,
Rendeiro AF,
Rathert P,
You W,
Lin JG,
Ringler A,
Hofstätter G,Moll HP,
Gürtl B,
Farlik M,
Schick S,
Klepsch F,
Oldach M,
Buphamalai P,Schischlik F,
Májek P,
Parapatics K,
Schmidl C,
Schuster M,
Penz T,
Buckley DL,Hudecz O,
Imre R,
Wang SY,
Maric HM,
Kralovics R,
Bennett KL,
Müller AC,
MechtlerK,
Menche J,
Bradner JE,
Winter GE,
Klavins K,
Casanova E,
Bock C,
Zuber J,Kubicek S.
Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27.
2019
Benefit of second-line systemic chemotherapy for advanced biliary tract cancer: A propensity score analysis.
Moik F,
Riedl JM,
Winder T,
Terbuch A,
Rossmann CH,
Szkandera J,
Bauernhofer T,
Kasparek AK,
Schaberl-Moser R,
Reicher A,
Prinz F,
Pichler M,
Stöger H,
Stotz M,
Gerger A,
Posch F.
Sci Rep. 2019 Apr 3;9(1):5548.doi: 10.1038/s41598-019-42069-1.
2019
Mapping the Human Kinome in Response to DNA Damage.
Owusu M,
Bannauer P,
Ferreira da Silva J,
Mourikis TP,
Jones A,
Májek P,Caldera M,
Wiedner M,
Lardeau CH,
Mueller AC,
Menche J,
Kubicek S,
Ciccarelli FD,Loizou JI.
Cell Rep. 2019 Jan15;26(3):555-563.e6. doi: 10.1016/j.celrep.2018.12.087.
2019
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL.
Schmidl C,
Vladimer GI,
Rendeiro AF,
Schnabl S,
Krausgruber T,
Taubert C,Krall N,
Pemovska T,
Araghi M,
Snijder B,
Hubmann R,
Ringler A,
Runggatscher K,Demirtas D,
de la Fuente OL,
Hilgarth M,
Skrabs C,
Porpaczy E,
Gruber M,
HoermannG,
Kubicek S,
Staber PB,
Shehata M,
Superti-Furga G,
Jäger U,
Bock C.
Nat Chem Biol. 2019 Mar;15(3):232-240. doi: 10.1038/s41589-018-0205-2. Epub 2019 Jan 28.
