Publications

2016

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

Mazouzi A, Stukalov A, Müller AC, Chen D, Wiedner M, Prochazkova J, Chiang SC, Schuster M, Breitwieser FP, Pichlmair A, El-Khamisy SF, Bock C, Kralovics R, Colinge J, Bennett KL, Loizou JI.
Cell Rep. 2016 Apr 14. pii: S2211-1247(16)30366-7. doi: 10.1016/j.celrep.2016.03.077.
2016

Uras, Barbara Mair, Abdelghani Mazouzi, Tereza Suchankova, Tomasz Konopka, Amanda M.

Michal Smida, Ferran Fece de la Cruz, Claudia Kerzendorfer, Iris Z.
Nature Communications 2016 Dec 6. doi:10.1038/NCOMMS13701
2016

Perturbed hematopoiesis in mice lacking ATMIN.

Anjos-Afonso F, Loizou JI, Bradburn A, Kanu N, Purewal S, Da Costa C, Bonnet D, Behrens A.
Blood 2016 Sep. doi:10.1182/blood-2015-09-672980.
2015

DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.

Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI.
PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015.
2015

Programmed DNA breaks in lymphoid cells: Repair mechanisms and consequences in human disease.

Prochazkova J, Loizou JI.
Immunology. 2015 Oct 12. doi: 10.1111/imm.12547.
2014

Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, Loizou JI.

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.
DNA Repair (Amst). 2014 Sep 24. pii: S1568-7864(14)00223-7. doi: 10.1016/j.dnarep.2014.09.001. [Epub ahead of print] PMID: 25262557.
2014

Mazouzi A, Velimezi G, Loizou JI.

DNA replication stress: Causes, resolution and disease.
Exp Cell Res. 2014 Sep 30. pii: S0014-4827(14)00435-2. doi: 10.1016/j.yexcr.2014.09.030. [Epub ahead of print] Review.PMID: 25281304.
2014

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.

Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G.
Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2.