CeMM position on genome editing in the light of recent reports about gene-edited babies
Following internal discussions at CeMM on human genome editing – prompted by recent reports on the birth of gene-edited babies using CRISPR technology in China – we distance ourselves from human trials performed without adequate ethical approval by the responsible institutions and in violation of both local regulations and the international consensus in the scientific community.
CeMM welcomes responsible research on understanding and advancing genome editing technology including CRISPR, which greatly benefits basic biomedical research and has great potential also for the treatment of many genetic diseases. Importantly, any such research must be performed in strict concordance with local, national, and international laws and regulations. Furthermore, it should be discussed and supported by the international scientific community, including biologists and medical researchers as well as ethicists, social scientists and various stakeholders of civil society, such as patients’ organizations.
There is broad consensus within the scientific community that editing of the human germline for human enhancement is entirely unacceptable. In contrast, genome editing to correct severe genetic diseases may be acceptable if there is a clear positive risk-benefit ratio, no suitable alternatives, comprehensive preparatory work supporting feasibility, full legal and regulatory compliance, and strong framework of ethical guidance and supervision.
CeMM is committed to participate in a broad societal dialog about CRISPR technology, genome editing, and other developments in the life sciences. It is important that these developments are not happening in perceived or actual secrecy at highly specialized research institutions, but that they are part of a broad discussion about chances and risks, and based on information, education and divulgation on all scientific, medical, ethical and societal aspects associated. CeMM is committed in fostering this debate and promoting genetic literacy in the general population.
To read more about the potential applications of CRISPR technology, and the use of it at CeMM, please download the <link https://cemm.at/fileadmin/img/CRISPR_Statement_CeMM_December_2018.pdf - external-link-new-window "Opens internal link in current window">full statement</link>.
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