Publications
2024
Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function
Valentina Stolz,
Rafael de Freitas E Silva,
Ramona Rica,
Ci Zhu,
Teresa Preglej,
Patricia Hamminger,
Daniela Hainberger,
Marlis Alteneder,
Lena Müller,
Monika Waldherr,
Darina Waltenberger,
Anastasiya Hladik,
Benedikt Agerer,
Michael Schuster,
Tobias Frey,
Thomas Krausgruber,
Sylvia Knapp,
Clarissa Campbell,
Klaus Schmetterer,
Michael Trauner,
Andreas Bergthaler,
Christoph Bock,
Nicole Boucheron,
Wilfried Ellmeier.
Elife. 2024 Oct 28;13:e78738. doi: 10.7554/eLife.78738.
2024
Insights into the multifaceted role of interleukin-37 on human immune cell regulation
Lisa U Teufel,
Vasiliki Matzaraki,
Lukas Folkman,
Rob Ter Horst,
Simone J C F M Moorlag,
Catharina M Mulders-Manders,
Mihai G Netea,
Thomas Krausgruber,
Leo A B Joosten,
Rob J W Arts.
Clin Immunol. 2024 Nov;268:110368. doi: 10.1016/j.clim.2024.110368. Epub 2024 Sep 20.
2024
GPT-4 as a biomedical simulator
Moritz Schaefer,
Stephan Reichl,
Rob Ter Horst,
Adele M Nicolas,
Thomas Krausgruber,
Francesco Piras,
Peter Stepper,
Christoph Bock,
Matthias Samwald.
Comput Biol Med. 2024 Aug;178:108796. doi: 10.1016/j.compbiomed.2024.108796. Epub 2024 Jun 22.
2024
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
Leon U B Enk,
Malte Hellmig,
Kristoffer Riecken,
Christoph Kilian,
Paul Datlinger,
Saskia L Jauch-Speer,
Tobias Neben,
Zeba Sultana,
Varshi Sivayoganathan,
Alina Borchers,
Hans-Joachim Paust,
Yu Zhao,
Nariaki Asada,
Shuya Liu,
Theodora Agalioti,
Penelope Pelczar,
Thorsten Wiech,
Christoph Bock,
Tobias B Huber,
Samuel Huber,
Stefan Bonn,
Nicola Gagliani,
Boris Fehse,
Ulf Panzer,
Christian F Krebs.
Sci Immunol. 2024 Jun 14;9(96):eadd6774. doi: 10.1126/sciimmunol.add6774. Epub 2024 Jun 14.
2024
Mapping the brain's gene-regulatory maze
Gaia Novarino,
Christoph Bock.
Science. 2024 May 24;384(6698):860-861. doi: 10.1126/science.adp4663. Epub 2024 May 23.
2024
JAK-STAT signaling maintains homeostasis in T cells and macrophages
Nikolaus Fortelny,
Matthias Farlik,
Victoria Fife,
Anna-Dorothea Gorki,
Caroline Lassnig,
Barbara Maurer,
Katrin Meissl,
Marlies Dolezal,
Laura Boccuni,
Aarathy Ravi Sundar Jose Geetha,
Mojoyinola Joanna Akagha,
Anzhelika Karjalainen,
Stephen Shoebridge,
Asma Farhat,
Ulrike Mann,
Rohit Jain,
Shweta Tikoo,
Nina Zila,
Wolfgang Esser-Skala,
Thomas Krausgruber,
Katarzyna Sitnik,
Thomas Penz,
Anastasiya Hladik,
Tobias Suske,
Sophie Zahalka,
Martin Senekowitsch,
Daniele Barreca,
Florian Halbritter,
Sabine Macho-Maschler,
Wolfgang Weninger,
Heidi A Neubauer,
Richard Moriggl,
Sylvia Knapp,
Veronika Sexl,
Birgit Strobl,
Thomas Decker,
Mathias Müller,
Christoph Bock.
Nat Immunol. 2024 May;25(5):847-859. doi: 10.1038/s41590-024-01804-1. Epub 2024 Apr 24.
2024
Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia
Tobias Suske,
Helena Sorger,
Gabriele Manhart,
Frank Ruge,
Nicole Prutsch,
Mark W Zimmerman,
Thomas Eder,
Diaaeldin I Abdallah,
Barbara Maurer,
Christina Wagner,
Susann Schönefeldt,
Katrin Spirk,
Alexander Pichler,
Tea Pemovska,
Carmen Schweicker,
Daniel Pölöske,
Emina Hubanic,
Dennis Jungherz,
Tony Andreas Müller,
Myint Myat Khine Aung,
Anna Orlova,
Ha Thi Thanh Pham,
Kerstin Zimmel,
Thomas Krausgruber,
Christoph Bock,
Mathias Müller,
Maik Dahlhoff,
Auke Boersma,
Thomas Rülicke,
Roman Fleck,
Elvin Dominic de Araujo,
Patrick Thomas Gunning,
Tero Aittokallio,
Satu Mustjoki,
Takaomi Sanda,
Sylvia Hartmann,
Florian Grebien,
Gregor Hoermann,
Torsten Haferlach,
Philipp Bernhard Staber,
Heidi Anne Neubauer,
Alfred Thomas Look,
Marco Herling,
Richard Moriggl.
J Clin Invest. 2024 Apr 15;134(8):e168536. doi: 10.1172/JCI168536.
2024
Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice
Zsofia Hevesi,
Joanne Bakker,
Evgenii O Tretiakov,
Csaba Adori,
Anika Raabgrund,
Swapnali S Barde,
Martino Caramia,
Thomas Krausgruber,
Sabrina Ladstätter,
Christoph Bock,
Tomas Hökfelt,
Tibor Harkany.
Nat Commun. 2024 Mar 29;15(1):2762. doi: 10.1038/s41467-024-47054-5.
2024
Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual
Katharina Kocher,
Carolin Moosmann,
Felix Drost,
Christine Schülein,
Pascal Irrgang,
Philipp Steininger,
Jahn Zhong,
Johannes Träger,
Bernd Spriewald,
Christoph Bock,
Dirk H Busch,
Christian Bogdan,
Benjamin Schubert,
Thomas H Winkler,
Matthias Tenbusch,
Ev-Marie Schuster,
Kilian Schober.
Lancet Infect Dis. 2024 May;24(5):e272-e274. doi: 10.1016/S1473-3099(24)00134-8. Epub 2024 Mar 4.
2024
One-carbon metabolism nutrients impact the interplay between DNA methylation and gene expression in liver, enhancing protein synthesis in Atlantic salmon
Takaya Saito,
Marit Espe,
Vibeke Vikeså,
Christoph Bock,
Tårn H Thomsen,
Anne-Catrin Adam,
Jorge M O Fernandes,
Kaja H Skjaerven.
Epigenetics. 2024 Dec;19(1):2318517. doi: 10.1080/15592294.2024.2318517. Epub 2024 Feb 25.
