Publications
2019
HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response.
Hamdane N,
Jühling F,
Crouchet E,
El Saghire H,
Thumann C,
Oudot MA,
BandieraS,
Saviano A,
Ponsolles C,
Roca Suarez AA,
Li S,
Fujiwara N,
Ono A,
Davidson I,Bardeesy N,
Schmidl C,
Bock C,
Schuster C,
Lupberger J,
Habersetzer F,
Doffoël M,Piardi T,
Sommacale D,
Imamura M,
Uchida T,
Ohdan H,
Aikata H,
Chayama K,Boldanova T,
Pessaux P,
Fuchs BC,
Hoshida Y,
Zeisel MB,
Duong FHT,
Baumert TF.
Gastroenterology. 2019 Jun;156(8):2313-2329.e7.doi: 10.1053/j.gastro.2019.02.038. Epub 2019 Mar 2.
2019
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach A,
Luginina A,
Marin E,
Brouillette RL,
Besserer-Offroy É,
Longpré JM,
Ishchenko A,
Popov P,
Patel N,
Fujimoto T,
Maruyama T,
Stauch B,
Ergasheva M,
Romanovskaia D,
Stepko A,
Kovalev K,
Shevtsov M,
Gordeliy V,
Han GW,
Katritch V,
Borshchevskiy V,
Sarret P,
Mishin A,
Cherezov V.
Nat Commun. 2019 Dec 6;10(1):5573. doi: 10.1038/s41467-019-13348-2.
2019
B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.
Griss J,
Bauer W,
Wagner C,
Simon M,
Chen M,
Grabmeier-Pfistershammer K,
Maurer-Granofszky M,
Roka F,
Penz T, Bock C,
Zhang G,
Herlyn M,
Glatz K,
Läubli H,
Mertz KD,
Petzelbauer P,
Wiesner T,
Hartl M,
Pickl WF,
Somasundaram R,
Steinberger P,
Wagner SN.
Nat Commun. 2019;10(1):4186. Published 2019 Sep 13. doi:10.1038/s41467-019-12160-2
2019
Epigenomics and Single-Cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.
Halbritter F,
Farlik M,
Schwentner R,
Jug G,
Fortelny N,
Schnöller T,
Pisa H,
Schuster LC,
Reinprecht A,
Czech T,
Gojo J,
Holter W,
Minkov M,
Bauer W,
Simonitsch-Klupp I,
Bock C,
Hutter C.
Cancer Discov. 2019 Oct;9(10):1406-1421. doi: 10.1158/2159-8290.CD-19-0138.
2019
Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants [published online ahead of print, 2019 Nov 21].
Korchynska S,
Krassnitzer M,
Malenczyk K,
Prasad RB,
Tretiakov EO,
Rehman S,
Cinquina V,
Gernedl V,
Farlik M,
Petersen J,
Hannes S,
Schachenhofer J,
Reisinger SN,
Zambon A,
Asplund O,
Artner I,
Keimpema E,
Lubec G,
Mulder J, Bock C,
Pollak DD,
Romanov RA,
Pifl C,
Groop L,
Hökfelt TG,
Harkany T.
EMBO J. 2019;e100882. doi:10.15252/embj.2018100882
2019
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation.
Miragaia RJ,
Gomes T,
Chomka A,
Jardine L,
Riedel A,
Hegazy AN,
Whibley N,
Tucci A,
Chen X,
Lindeman I,
Emerton G,
Krausgruber T,
Shields J,
Haniffa M,
Powrie F,
Teichmann SA.
Immunity. 2019 Feb 19;50(2):493-504.e7. doi: 10.1016/j.immuni.2019.01.001.
2019
Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells.
Piper CJM,
Rosser EC,
Oleinika K,
Nistala K,
Krausgruber T,
Rendeiro AF,
Banos A,
Drozdov I,
Villa M,
Thomson S,
Xanthou G, Bock C,
Stockinger B,
Mauri C.
Cell Rep. 2019;29(7):1878–1892.e7. doi:10.1016/j.celrep.2019.10.018
2019
CDK6 coordinates JAK2V617F mutant MPN via NF-κB and apoptotic networks.
Uras IZ,
Maurer B,
Nivarthi H,
Jodl P,
Kollmann K,
Prchal-Murphy M,
Milosevic Feenstra JD,
Zojer M,
Lagger S,
Grausenburger R,
Grabner B,
Holly R,
Kavirayani A, Bock C,
Gisslinger H,
Valent P,
Kralovics R,
Sexl V.
Blood. 2019;133(15):1677–1690. doi:10.1182/blood-2018-08-872648
2019
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.
Schick S,
Rendeiro AF,
Runggatscher K,
Ringler A,
Boidol B,
Hinkel M,
Májek P,
Vulliard L,
Penz T,
Parapatics K,
Schmidl C,
Menche J,
Boehmelt G,
Petronczki M,
Müller AC, Bock C,
Kubicek S.
Nat Genet. 2019;51(9):1399–1410. doi:10.1038/s41588-019-0477-9
2019
Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection.
Ulz P,
Perakis S,
Zhou Q,
Moser T,
Belic J,
Lazzeri I,
Wölfler A,
Zebisch A,
Gerger A,
Pristauz G,
Petru E,
White B,
Roberts CES,
John JS,
Schimek MG,
Geigl JB,
Bauernhofer T,
Sill H, Bock C,
Heitzer E,
Speicher MR.
Nat Commun. 2019;10(1):4666. Published 2019 Oct 11. doi:10.1038/s41467-019-12714-4
