Publications
2018
Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells.
Barakat TS,
Halbritter F,
Zhang M,
Rendeiro AF,
Perenthaler E,
Bock C,
Chambers I.
Cell Stem Cell. 2018 Aug 2;23(2):276-288.e8. doi: 10.1016/j.stem.2018.06.014. Epub 2018 Jul 19.
2018
CDK6 antagonizes p53-induced responses during tumorigenesis.
Bellutti F,
Tigan AS,
Nebenfuehr S,
Dolezal M,
Zojer M,
Grausenburger R,
Hartenberger S,
Kollmann S,
Doma E,
Prchal-Murphy M,
Uras IZ,
Höllein A,
Neuberg DS,
Ebert BL,
Ringler A,
Mueller AC,
Loizou JI,
Hinds PW,
Vogl C,
Heller G,
Kubicek S,
Zuber J,
Malumbres M,
Farlik M,
Villunger A,
Kollmann K,
Sexl V.
Cancer Discov. 2018 Jun 13. pii: CD-17-0912. doi: 10.1158/2159-8290.CD-17-0912. [Epub ahead of print]
2018
Coloc-stats: a unified web interface to perform colocalization analysis of genomic features.
Simovski B,
Kanduri C,
Gundersen S,
Titov D,
Domanska D,
Bock C,
Bossini-Castillo L,
Chikina M,
Favorov A,
Layer RM,
Mironov AA,
Quinlan AR,
Sheffield NC,
Trynka G,
Sandve GK.
Nucleic Acids Res. 2018 Jun 5. doi: 10.1093/nar/gky474. [Epub ahead of print]
2018
An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.
Baumgartner C,
Toifl S,
Farlik M,
Halbritter F,
Scheicher R,
Fischer I,
Sexl V,
Bock C,
Baccarini M.
Cell Stem Cell. 2018 Jun 1;22(6):879-892.e6. doi: 10.1016/j.stem.2018.05.003. Epub 2018 May 24.
2018
MIRA: An R package for DNA methylation-based inference of regulatory activity.
Lawson JT,
Tomazou EM,
Bock C,
Sheffield NC.
Bioinformatics. 2018 Mar 1. doi: 10.1093/bioinformatics/bty083. [Epub ahead of print]
2018
Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species.
Lowe R,
Barton C,
Jenkins CA,
Ernst C,
Forman O,
Fernandez-Twinn DS,
Bock C,
Rossiter SJ,
Faulkes CG,
Ozanne SE,
Walter L,
Odom DT,
Mellersh C,
Rakyan VK.
Genome Biol. 2018 Feb 16;19(1):22. doi: 10.1186/s13059-018-1397-1.
2018
Parental micronutrient deficiency distorts liver DNA methylation and expression of lipid genes associated with a fatty-liver-like phenotype in offspring.
Skjærven KH,
Jakt LM,
Fernandes JMO,
Dahl JA,
Adam AC,
Klughammer J,
Bock C,
Espe M.
Sci Rep. 2018 Feb 14;8(1):3055. doi: 10.1038/s41598-018-21211-5.
2018
Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.
Aldape K,
Amin SB,
Ashley DM,
Barnholtz-Sloan JS,
Bates AJ,
Beroukhim R,
Bock C,
Brat DJ,
Claus EB,
Costello JF,
de Groot JF,
Finocchiaro G,
French PJ,
Gan HK,
Griffith B,
Herold-Mende CC,
Horbinski C,
Iavarone A,
Kalkanis SN,
Karabatsou K,
Kim H,
Kouwenhoven MCM,
McDonald KL,
Miletic H,
Nam DH,
Ng HK,
Niclou SP,
Noushmehr H,
Ormond R,
Poisson LM,
Reifenberger G,
Roncaroli F,
Sa JK,
Sillevis Smitt PAE,
Smits M,
Souza CF,
Tabatabai G,
Van Meir EG,
Verhaak RGW,
Watts C,
Wesseling P,
Woehrer A,
Yung WKA,
Jungk C,
Hau AC,
van Dyck E,
Westerman BA,
Yin J,
Abiola O,
Zeps N,
Grimmond S,
Buckland M,
Khasraw M,
Sulman EP,
Muscat AM,
Stead L; GLASS Consortium.
Neuro Oncol. 2018 Feb 8. doi: 10.1093/neuonc/noy020. [Epub ahead of print]
2018
STAT5BN642H is a driver mutation for T cell neoplasia.
Pham HTT,
Maurer B,
Prchal-Murphy M,
Grausenburger R,
Grundschober E,
Javaheri T,
Nivarthi H,
Boersma A,
Kolbe T,
Elabd M,
Halbritter F,
Pencik J,
Kazemi Z,
Grebien F,
Hengstschläger M,
Kenner L,
Kubicek S,
Farlik M,
Bock C,
Valent P,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
J Clin Invest. 2018 Jan 2;128(1):387-401. doi: 10.1172/JCI94509. Epub 2017 Dec 4.
2018
A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.
Göschl L,
Preglej T,
Hamminger P,
Bonelli M,
Andersen L,
Boucheron N,
Gülich AF,
Müller L,
Saferding V,
Mufazalov IA,
Hirahara K,
Seiser C,
Matthias P,
Penz T,
Schuster M,
Bock C,
Waisman A,
Steiner G,
Ellmeier W.
J Autoimmun. 2018 Jan;86:51-61. doi: 10.1016/j.jaut.2017.09.008. Epub 2017 Sep 28.
