Publications
2019
NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.
Simonović N,
Witalisz-Siepracka A,
Meissl K,
Lassnig C,
Reichart U,
Kolbe T,
Farlik M,
Bock C,
Sexl V,
Müller M,
Strobl B.
J Immunol. 2019 Mar 15;202(6):1724-1734. doi: 10.4049/jimmunol.1701649.Epub 2019 Feb 4.
2019
Growth dynamics in naturally progressing chronic lymphocytic leukaemia.
Gruber M,
Bozic I,
Leshchiner I,
Livitz D,
Stevenson K,
Rassenti L,
RosebrockD,
Taylor-Weiner A,
Olive O,
Goyetche R,
Fernandes SM,
Sun J,
Stewart C,
Wong A,
Cibulskis C,
Zhang W,
Reiter JG,
Gerold JM,
Gribben JG,
Rai KR,
Keating MJ,
BrownJR,
Neuberg D,
Kipps TJ,
Nowak MA,
Getz G,
Wu CJ.
Nature. 2019 Jun;570(7762):474-479.doi: 10.1038/s41586-019-1252-x. Epub 2019 May 29.
2019
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease.
Kosack L,
Wingelhofer B,
Popa A,
Orlova A,
Agerer B,
Vilagos B,
Majek P,Parapatics K,
Lercher A,
Ringler A,
Klughammer J,
Smyth M,
Khamina K,
Baazim H,de Araujo ED,
Rosa DA,
Park J,
Tin G,
Ahmar S,
Gunning PT,
Bock C,
Siddle HV,Woods GM,
Kubicek S,
Murchison EP,
Bennett KL,
Moriggl R,
Bergthaler A.
Cancer Cell. 2019Jan 14;35(1):125-139.e9. doi: 10.1016/j.ccell.2018.11.018.
2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Sdelci S,
Rendeiro AF,
Rathert P,
You W,
Lin JG,
Ringler A,
Hofstätter G,Moll HP,
Gürtl B,
Farlik M,
Schick S,
Klepsch F,
Oldach M,
Buphamalai P,Schischlik F,
Májek P,
Parapatics K,
Schmidl C,
Schuster M,
Penz T,
Buckley DL,Hudecz O,
Imre R,
Wang SY,
Maric HM,
Kralovics R,
Bennett KL,
Müller AC,
MechtlerK,
Menche J,
Bradner JE,
Winter GE,
Klavins K,
Casanova E,
Bock C,
Zuber J,Kubicek S.
Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27.
2019
RnBeads 2.0: comprehensive analysis of DNA methylation data.
Müller F,
Scherer M,
Assenov Y,
Lutsik P,
Walter J,
Lengauer T,
Bock C.
0: comprehensive analysis of DNA methylation data. Genome Biol. 2019Mar 14;20(1):55. doi: 10.1186/s13059-019-1664-9.
2019
Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells.
Puhm F,
Afonyushkin T,
Resch U,
Obermayer G,
Rohde M,
Penz T,
Schuster M,Wagner G,
Rendeiro AF,
Melki I,
Kaun C,
Wojta J,
Bock C,
Jilma B,
Mackman N,Boilard E,
Binder CJ.
Circ Res. 2019 Jun 21;125(1):43-52. doi:10.1161/CIRCRESAHA.118.314601. Epub 2019 May 8.
2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.
Schischlik F,
Jäger R,
Rosebrock F,
Hug E,
Schuster M,
Holly R,
Fuchs E,Milosevic Feenstra JD,
Bogner E,
Gisslinger B,
Schalling M,
Rumi E,
Pietra D,Fischer G,
Faé I,
Vulliard L,
Menche J,
Haferlach T,
Meggendorfer M,
Stengel A,Bock C,
Cazzola M,
Gisslinger H,
Kralovics R.
Blood. 2019 Jul 11;134(2):199-210. doi: 10.1182/blood.2019000519. Epub2019 May 7.
2019
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL.
Schmidl C,
Vladimer GI,
Rendeiro AF,
Schnabl S,
Krausgruber T,
Taubert C,Krall N,
Pemovska T,
Araghi M,
Snijder B,
Hubmann R,
Ringler A,
Runggatscher K,Demirtas D,
de la Fuente OL,
Hilgarth M,
Skrabs C,
Porpaczy E,
Gruber M,
HoermannG,
Kubicek S,
Staber PB,
Shehata M,
Superti-Furga G,
Jäger U,
Bock C.
Nat Chem Biol. 2019 Mar;15(3):232-240. doi: 10.1038/s41589-018-0205-2. Epub 2019 Jan 28.
2019
CRISPR/Cas9 guided genome and epigenome engineering and its therapeutic applications in immune mediated diseases.
Singh DD,
Hawkins RD,
Lahesmaa R,
Tripathi SK.
Semin Cell Dev Biol. 2019 Jun 19. pii: S1084-9521(18)30111-3. doi:10.1016/j.semcdb.2019.05.007. [Epub ahead of print] Review.
2019
Spatiotemporal structure of cell fate decisions in murine neural crest.
Soldatov R,
Kaucka M,
Kastriti ME,
Petersen J,
Chontorotzea T,
Englmaier L,Akkuratova N,
Yang Y,
Häring M,
Dyachuk V,
Bock C,
Farlik M,
Piacentino ML,Boismoreau F,
Hilscher MM,
Yokota C,
Qian X,
Nilsson M,
Bronner ME,
Croci L,Hsiao WY,
Guertin DA,
Brunet JF,
Consalez GG,
Ernfors P,
Fried K,
Kharchenko PV,
Adameyko I.
Science. 2019 Jun 7;364(6444). pii: eaas9536. doi:10.1126/science.aas9536.
