2015

Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection.

Sommerstein R, Flatz L, Remy MM, Malinge P, Magistrelli G, Fischer N, Sahin M, Bergthaler A, Igonet S, Ter Meulen J, Rigo D, Meda P, Rabah N, Coutard B, Bowden TA, Lambert PH, Siegrist CA, Pinschewer DD.
PLoS Pathog. 2015 Nov 20;11(11):e1005276. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/26587982
2014

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.

Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett AL, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein MM, Symer DE, Aderem A, Bergthaler A.
Nature Immunology. 2014 Nov 24.
2015

Protective Efficacy of Individual CD8+ T Cell Specificities in Chronic Viral Infection.

Johnson S*, Bergthaler A*, Graw F, Flatz L, Bonilla WV, Siegrist CA, Lambert PH, Regoes RR, Pinschewer DD.
J Immunol. 2015 Feb 15;194(4):1755-62. doi: 10.4049/jimmunol.1401771. Epub 2015 Jan 7. (* these authors contributed equally)
2015

Superoxide dismutase 1 protects from type I interferon-driven oxidative damage in viral hepatitis.

Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Schliehe C, Panse I, Vilagos B, Khamina K, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A.
Immunity Volume 43, Issue 5, p974–986, 17 November 2015.
2013

Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.

Kreutzfeldt M, Bergthaler A, Fernandez M, Brück W, Steinbach K, Vorm M, Coras R, Blümcke I, Bonilla WV, Fleige A, Forman R, Müller W, Becher B, Misgeld T, Kerschensteiner M, Pinschewer DD, Merkler D.
J Exp Med. 2013 Sep 23;210(10):2087-103. doi: 10.1084/jem.20122143. Epub 2013 Sep 2.
2012

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.

Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A.
Nature. 2012 Oct 18;490(7420):421-5.