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Andreas Bergthaler

Andreas Bergthaler

Systemic Immunometabolism in Viral Infection and Advanced Pathogen Surveillance on the Population Level

2019

Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.

Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T.
 JCI Insight. 2019;4(20):e124164. Published 2019 Oct 17. doi:10.1172/jci.insight.124164
2018

Human tripartite motif protein 52 is required for cell context-dependent proliferation.

Benke S, Agerer B, Haas L, Stöger M, Lercher A, Gabler L, Kiss I, Scinicariello S, Berger W, Bergthaler A, Obenauf AC, Versteeg GA.
Oncotarget. 2018 Feb 5;9(17):13565-13581. doi: 10.18632/oncotarget.24422. eCollection 2018 Mar 2.
2017

Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.

Khamina K , Lercher  A , Caldera M, Schliehe C , Vilagos B , Sahin M, Kosack L, Bhattacharya A, Májek P, Stukalov A, Sacco R, James LC, Pinschewer DD, Bennett KL, Menche J, Bergthaler A.
PLoS Pathogens 13(12): e1006758; 2017.
2017

The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis.

Kosack L, Gawish R, Lercher A, Vilagos B, Hladik A, Lakovits K, Bhattacharya A, Schliehe C, Mesteri I, Knapp S, Bergthaler A.
Sci Rep. 2017 Sep 12;7(1):11289. doi: 10.1038/s41598-017-10637-y.
2017

The immune system as a social network.

Bergthaler A, Menche J.
Nat Immunol. 2017 Apr 18;18(5):481-482. doi: 10.1038/ni.3727. No abstract available.
2017

Vaccinia virus G1 protein: absence of autocatalytic self-processing.

Leite FGG, Bergthaler A, Skern T.
Arch Virol. 2017 May 18. doi: 10.1007/s00705-017-3409-y. [Epub ahead of print]
2017

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation.

Hegazy AN, West NR, Stubbington MJT, Wendt E, Suijker KIM, Datsi A, This S, Danne C, Campion S, Duncan SH, Owens BMJ, Uhlig HH, McMichael A; Oxford IBD Cohort Investigators, Bergthaler A, Teichmann SA, Keshav S, Powrie F.
Gastroenterology. 2017 Nov;153(5):1320-1337.e16. doi: 10.1053/j.gastro.2017.07.047. Epub 2017 Aug 4.
2017

The fitness cost of mis-splicing is the main determinant of alternative splicing patterns.

Saudemont B, Popa A, Parmley JL, Rocher V, Blugeon C, Necsulea A, Meyer E, Duret L.
Genome Biol. 2017 Oct 30;18(1):208. doi: 10.1186/s13059-017-1344-6.
2016

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.
Cell Rep. 2016 Sep 20;16(12):3311-21. doi: 10.1016/j.celrep.2016.08.056.
2016

MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.

Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181.