2025
Author Correction: CD8+ T cells induce cachexia during chronic viral infection
Hatoon Baazim,
Martina Schweiger,
Michael Moschinger,
Haifeng Xu,
Thomas Scherer,
Alexandra Popa,
Suchira Gallage,
Adnan Ali,
Kseniya Khamina,
Lindsay Kosack,
Bojan Vilagos,
Mark Smyth,
Alexander Lercher,
Joachim Friske,
Doron Merkler,
Alan Aderem,
Thomas H Helbich,
Mathias Heikenwälder,
Philipp A Lang,
Rudolf Zechner,
Andreas Bergthaler.
Nat Immunol. 2026 Jan;27(1):166. doi: 10.1038/s41590-025-02369-3.
2025
A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis
Tuan-Anh Nguyen,
Jung-Ming G Lin,
Anne-Sophie M C Marques,
Maximilian Fottner,
Ludwig G Bauer,
Andreas Reicher,
Diana Daum,
Lorenzo Scrofani,
Yusi Liu,
Carol Cheng,
Luna D'Angelo L D D,
Juan Sanchez,
Christoph Bueschl,
Nara Marella,
Pisanu Buphamalai,
Florian Traversi,
Maša Bereš,
Herwig P Moll,
Marton Siklos,
Jakob-Wendelin Genger,
Gerald Hofstaetter,
Ludovica Villanti,
Monika Malik,
Christoph Klimek,
Kathrin Runggatscher,
Bettina Guertl,
Jesper S Hansen,
Sarah Dobner,
Olga Babosova,
Tina Becirovic,
Laura P M H de Rooij,
Emilio Casanova,
Anna Koren,
D Sean Froese,
David S Rosenblatt,
Kristaps Klavins,
Andreas Bergthaler,
Jörg Menche,
J Thomas Hannich,
Miriam Abele,
Sara Sdelci,
Kathrin Lang,
Kilian V M Huber,
Stefan Kubicek.
Science. 2025 Dec 11;390(6778):1143-1150. doi: 10.1126/science.adv4257. Epub 2025 Nov 6.
2025
Tyrosine kinase targeting uncovers oncogenic pathway plasticity in Tasmanian devil transmissible cancers
Anna Schönbichler,
Anna Orlova,
Carmen Kreindl,
Lukas Endler,
Richard Wilson,
Lindsay Kosack,
Anna Hofmann,
Csilla Viczenczova,
Jocelyn Darby,
Fettah Erdogan,
Amanda L Patchett,
Anna Koren,
Stefan Kubicek,
Mathias Müller,
Andrew S Flies,
Andreas Bergthaler,
Richard Moriggl.
EMBO J. 2025 Nov 3. doi: 10.1038/s44318-025-00603-0. Online ahead of print.
2025
Mitochondrial ROS drive foam cell formation via STAT5 signaling in atherosclerosis
Laura Boccuni,
Frieda Marka,
Manuel Salzmann,
Alessia Schirripa,
Elisabeth Ableitner,
Magdalena Siller,
Mira Brekalo,
Patrick Haider,
Stefan Stojkovic,
Christoph Neumayer,
Tiit Örd,
Karoline Kollmann,
Alice Assinger,
Thomas Decker,
Thomas Köcher,
Michael B Fischer,
Marion Mußbacher,
Andreas Bergthaler,
Christian Hengstenberg,
Bruno K Podesser,
Minna U Kaikkonen,
Johann Wojta,
Philipp J Hohensinner.
Sci Adv. 2025 Aug 29;11(35):eadw9952. doi: 10.1126/sciadv.adw9952. Epub 2025 Aug 27.
2025
EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer
Dana Krauß,
Veronica Moreno-Viedma,
Emi Adachi-Fernandez,
Cristiano de Sá Fernandes,
Jakob-Wendelin Genger,
Ourania Fari,
Bernadette Blauensteiner,
Dominik Kirchhofer,
Nikolina Bradaric,
Valeriya Gushchina,
Georgios Fotakis,
Thomas Mohr,
Ifat Abramovich,
Inbal Mor,
Martin Holcmann,
Andreas Bergthaler,
Arvand Haschemi,
Zlatko Trajanoski,
Juliane Winkler,
Eyal Gottlieb,
Maria Sibilia.
EMBO Mol Med. 2025 Jun;17(6):1355-1392. doi: 10.1038/s44321-025-00240-4. Epub 2025 May 6.
2025
Analysis insights to support the use of wastewater and environmental surveillance data for infectious diseases and pandemic preparedness
K M O'Reilly,
M J Wade,
K Farkas,
F Amman,
A Lison,
J D Munday,
J Bingham,
Z E Mthombothi,
Z Fang,
C S Brown,
R R Kao,
L Danon.
Epidemics. 2025 Jun;51:100825. doi: 10.1016/j.epidem.2025.100825. Epub 2025 Mar 28.
2025
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation
Ci Zhu,
Nicole Boucheron,
Osamah Al-Rubaye,
Brian K Chung,
Liv Wenche Thorbjørnsen,
Thomas Köcher,
Michael Schuster,
Thierry Claudel,
Emina Halilbasic,
Victoria Kunczer,
Fanziska Muscate,
Lois L Cavanagh,
Darina Waltenberger,
Alexander Lercher,
Anna Ohradanova-Repic,
Philipp Schatzlmaier,
Tatjana Stojakovic,
Hubert Scharnagl,
Andreas Bergthaler,
Hannes Stockinger,
Samuel Huber,
Christoph Bock,
Lukas Kenner,
Tom H Karlsen,
Wilfried Ellmeier,
Michael Trauner.
Gut. 2025 Jun 6;74(7):1079-1093. doi: 10.1136/gutjnl-2024-333297.
2024
Optimising Transformation Efficiency in Borrelia: Unravelling the Role of the Restriction-Modification System of Borrelia afzelii and Borrelia garinii
Margarida Ruivo,
Noémi Zsuzsa Kovács,
Anna-Margarita Schötta,
Theresa Stelzer,
Laura Hermann,
Verena Mündler,
Andreas Bergthaler,
Michael Reiter,
Michiel Wijnveld.
Int J Mol Sci. 2024 Oct 22;25(21):11343. doi: 10.3390/ijms252111343.
2024
Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function
Valentina Stolz,
Rafael de Freitas E Silva,
Ramona Rica,
Ci Zhu,
Teresa Preglej,
Patricia Hamminger,
Daniela Hainberger,
Marlis Alteneder,
Lena Müller,
Monika Waldherr,
Darina Waltenberger,
Anastasiya Hladik,
Benedikt Agerer,
Michael Schuster,
Tobias Frey,
Thomas Krausgruber,
Sylvia Knapp,
Clarissa Campbell,
Klaus Schmetterer,
Michael Trauner,
Andreas Bergthaler,
Christoph Bock,
Nicole Boucheron,
Wilfried Ellmeier.
Elife. 2024 Oct 28;13:e78738. doi: 10.7554/eLife.78738.
2024
Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection
Katja Knapp,
Romana Klasinc,
Anna Koren,
Magdalena Siller,
Ruth Dingelmaier-Hovorka,
Mathias Drach,
Juan Sanchez,
David Chromy,
Marlene Kranawetter,
Christoph Grimm,
Andreas Bergthaler,
Stefan Kubicek,
Hannes Stockinger,
Georg Stary.
Cell Rep Med. 2024 Jul 16;5(7):101643. doi: 10.1016/j.xcrm.2024.101643. Epub 2024 Jul 8.
