Publications
2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Sdelci S,
Rendeiro AF,
Rathert P,
You W,
Lin JG,
Ringler A,
Hofstätter G,Moll HP,
Gürtl B,
Farlik M,
Schick S,
Klepsch F,
Oldach M,
Buphamalai P,Schischlik F,
Májek P,
Parapatics K,
Schmidl C,
Schuster M,
Penz T,
Buckley DL,Hudecz O,
Imre R,
Wang SY,
Maric HM,
Kralovics R,
Bennett KL,
Müller AC,
MechtlerK,
Menche J,
Bradner JE,
Winter GE,
Klavins K,
Casanova E,
Bock C,
Zuber J,Kubicek S.
Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27.
2019
Identification and characterization of cancer vulnerabilities via targeted protein degradation.
Mayor-Ruiz C,
Winter GE.
Drug Discov Today Technol. 2019Apr;31:81-90. doi: 10.1016/j.ddtec.2018.12.003. Epub 2019 Jan 2. Review.
2019
Locus-Specific Knock-In of a Degradable Tag for Target Validation Studies.
Brand M,
Winter GE.
Methods Mol Biol. 2019;1953:105-119. doi:10.1007/978-1-4939-9145-7_7.
2019
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation.
Mayor-Ruiz C,
Jaeger MG,
Bauer S,
Brand M,
Sin C,
Hanzl A,
Mueller AC,
Menche J,
Winter GE.
Mol Cell. 2019 Aug 22;75(4):849-858.e8. doi: 10.1016/j.molcel.2019.07.013.
2019
Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells.
Ferreira da Silva J,
Salic S,
Wiedner M,
Datlinger P,
Essletzbichler P,
Hanzl A,
Superti-Furga G,
Bock C,
Winter G,
Loizou JI.
Sci Rep. 2019 Oct 31;9(1):15751. doi: 10.1038/s41598-019-52078-9.
2019
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML.
Brand M,
Jiang B,
Bauer S,
Donovan KA,
Liang Y,
Wang ES,
Nowak RP,
Yuan JC,Zhang T,
Kwiatkowski N,
Müller AC,
Fischer ES,
Gray NS,
Winter GE.
Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. doi:10.1016/j.chembiol.2018.11.006. Epub 2018 Dec 27.
2019
Stick it to E3s.
Brand M,
Winter GE.
Nat Chem Biol. 2019 Jul;15(7):655-656.doi: 10.1038/s41589-019-0312-8.
