Publications
2021
Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.
Valent P,
Orfao A,
Kubicek S,
Staber P,
Haferlach T,
Deininger M,
Kollmann K,
Lion T,
Virgolini I,
Winter G,
Hantschel O,
Kenner L,
Zuber J,
Grebien F,
Moriggl R,
Hoermann G,
Hermine O,
Andreeff M,
Bock C,
Mughal T,
Constantinescu SN,
Kralovics R,
Sexl V,
Skoda R,
Superti-Furga G,
Jäger U.
Hemasphere. 2021 Feb 17;5(3):e536. doi: 10.1097/HS9.0000000000000536. eCollection 2021 Mar.
2021
Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C,
Bauer S,
Brand M,
Kozicka Z,
Siklos M,
Imrichova H,
Kaltheuner IH,
Hahn E,
Seiler K,
Koren A,
Petzold G,
Fellner M,
Bock C,
Müller AC,
Zuber J,
Geyer M,
Thomä NH,
Kubicek S,
Winter GE.
Nat Chem Biol. 2021 Mar;17(3):361. doi: 10.1038/s41589-021-00735-4.
2021
Fast-acting chemical tools to delineate causality in transcriptional control.
Jaeger MG,
Winter GE.
Mol Cell. 2021 Apr 15;81(8):1617-1630. doi: 10.1016/j.molcel.2021.02.015. Epub 2021 Mar 8.
2021
The role of reversible and irreversible covalent chemistry in targeted protein degradation.
Kiely-Collins H,
Winter GE,
Bernardes GJL.
Cell Chem Biol. 2021 Mar 25:S2451-9456(21)00144-6. doi: 10.1016/j.chembiol.2021.03.005. Online ahead of print.
2021
Identification and selectivity profiling of small-molecule degraders via multi-omics approaches.
Scholes NS,
Mayor-Ruiz C,
Winter GE.
Cell Chem Biol. 2021 Mar 29:S2451-9456(21)00146-X. doi: 10.1016/j.chembiol.2021.03.007. Online ahead of print.
2020
Targeted protein degradation: current and future challenges.
Hanzl A,
Winter GE.
Curr Opin Chem Biol. 2020 Jun;56:35-41. doi: 10.1016/j.cbpa.2019.11.012. Epub 2020 Jan 2. PMID: 31901786.
2020
Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis.
Bensimon A,
Pizzagalli MD,
Kartnig F,
Dvorak V,
Essletzbichler P,
Winter GE,
Superti-Furga G.
Cell Chem Biol. 2020 Jun 18;27(6):728-739.e9. doi: 10.1016/j.chembiol.2020.04.003. Epub 2020 May 7.
2020
Selective Mediator dependence of cell-type-specifying transcription.
Jaeger MG,
Schwalb B,
Mackowiak SD,
Velychko T,
Hanzl A,
Imrichova H,
Brand M,
Agerer B,
Chorn S,
Nabet B,
Ferguson FM,
Müller AC,
Bergthaler A,
Gray NS,
Bradner JE,
Bock C,
Hnisz D,
Cramer P,
Winter GE.
Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1.
2020
Rational discovery of molecular glue degraders via scalable chemical profiling.
Mayor-Ruiz C,
Bauer S,
Brand M,
Kozicka Z,
Siklos M,
Imrichova H,
Kaltheuner IH,
Hahn E,
Seiler K,
Koren A,
Petzold G,
Fellner M,
Bock C,
Müller AC,
Zuber J,
Geyer M,
Thomä NH,
Kubicek S,
Winter GE.
Nat Chem Biol. 2020 Nov;16(11):1199-1207. doi: 10.1038/s41589-020-0594-x. Epub 2020 Aug 3. Erratum in: Nat Chem Biol. 2021 Mar;17(3):361.
2020
Direct stimulation of ERBB2 highlights a novel cytostatic signaling pathway driven by the receptor Thr(701) phosphorylation.
Gaviraghi M,
Rabellino A,
Andolfo A,
Brand M,
Brombin C,
Bagnato P,
De Feudis G,
Raimondi A,
Locatelli A,
Tosoni D,
Mazza D,
Gianni L,
Tonon G,
Yarden Y,
Tacchetti C,
Daniele T.
Sci Rep. 2020 Oct 9;10(1):16906. doi: 10.1038/s41598-020-73835-1.
