Become a Starting Principal Investigator at CeMM
We are currently searching for innovative, creative, ambitious scientists to become a CeMM Starting Principal Investigator and to join our highly committed CeMM Faculty working hard and having fun conceiving and exploring new precision medicine approaches and contributing to revolutionize the medicine of the future. • Do you want to join the CeMM Faculty, an international group of highly collaborative and supportive colleagues, who help you to…
Focus on Austrian Metabolic Research: 2nd AustroMetabolism Workshop
On Wednesday 9 October 2019, around 120 researches from 15 institutions from all over Austria gathered for the second time for the AustroMetabolism Workshop at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna.AustroMetabolism is an interdisciplinary event, which aims at providing a space for Austrian basic and clinical researchers in the field of metabolic research to network, and also promoting scientific…
CeMM Outing 2019
On Friday, 4 October 2019 our yearly CeMM Outing took place, bringing together our CeMMies and adjunct members for an excursion. We enjoyed a day full of interesting talks and social activities outside the Institute. This year’s special focus was on materials and material testing. Miriam Unterlass, CeMM Adjunct PI and Assistant Professor at the Technical University of Vienna, kicked off the event by discussing materials in the context of…
EU-LIFE urges the EU Council and the European Parliament to prioritise R&I by committing an appropriate budget for Horizon Europe
EU-LIFE, the alliance of 13 leading Life Science Research Institutes in Europe urges the EU Council and the European Parliament to double Horizon Europe’s budget compared to Horizon 2020 (H2020), to 150 Billion Euros and within it, to double the budget for discovery research, including the well-proven European Research Council. In addition, we strongly support the position of the President of the European Parliament, Mr. David Sassoli, on the…
New factor in the development of childhood lymphoma
The immune system is highly complex and a detailed understanding of many underlying mechanisms is still lacking. Only the precise interaction of a variety of factors guarantees a reliable and correct immune response in a healthy body. Misregulated immune responses are a major cause of a variety of diseases, including cancer, autoimmunity, and immune deficiency. A study recently published in the renowned journal Blood, led by Kaan Boztug…
CeMM PI Andreas Bergthaler nominated "Austrian of the Year 2019, Category Research"
We congratulate CeMM PI Andreas Bergthaler, who has been nominated “Austrian of the Year 2019” in the "Research" category. Join us in supporting Andreas’ work and nomination! Vote for Andreas Bergthaler <link https://diepresse.com/unternehmen/austria19/5082997/index?cat=2 _blank external-link-new-window "Opens internal link in current window">via the online system.</link> The #Austria19 award is organized by the newspaper Die Presse in…
ERC Starting Grant for CeMM PI Georg Winter
Georg Winter, CeMM Principal Investigator has received a prestigious Starting Grant of the European Research Council (ERC) for his research proposal “Glue2Degrade: Therapeutic hijacking of E3 Ligases”. The project will be funded with 1.3 € million over a period of five years. With his research proposal Georg Winter addresses a timely and important problem, trying to fill a gap in drug development and cancer research. The Glue2Degrade project…
Novel immunodeficiency syndrome amidst immunity and carcinogenesis
For the first time, a study led by Kaan Boztug, Scientific Director of St. Anna Children's Cancer Research Institute, unveils a hitherto unknown immune deficiency syndrome, which is based on a reduced functionality of the enzyme complex polymerase δ, an essential controller in DNA replication. Mutations affecting its function lead to genomic instability, neurodevelopmental disorders and immunodeficiency. The study was recently published in the…
A molecular "Trojan Horse"
Nuno Maulide's group from the Faculty of Chemistry of the University of Vienna has, in cooperation with Stefan Kubicek's lab at CeMM, achieved the synthesis of a potential immunosuppressive agent by modification of a naturally occurring compound. In this endeavour, the researchers have employed a masking trick to "hide" a reactive species inside the target molecule. The results were recently published in the renowned "Journal of the American…
Novel paradigm in drug development: Understanding resistance mechanisms to targeted protein degradation
Targeted protein degradation (TPD) is a new paradigm in drug discovery that could lead to the development of new medicines to treat diseases such as cancer more effectively. A recent study by researchers at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences reveals global and drug-specific cellular effectors needed for TPD. The results have now been published in the scientific journal Molecular Cell. Traditional…
CeMM International Postdoc Program (Vienna, Austria)
Pre-ERC Postdoc Program in Cellular, Molecular and Digital Medicine We are recruiting a group of postdocs (13 positions available) who are eager to pursue groundbreaking biomedical research, and we will help them to establish themselves as future scientific leaders. This postdoc program is designed to prepare postdoctoral researchers for a successful ERC Starting Grant application and for an independent research career in top research…
BAFfling cancer growth strategies: new targets for chromatin remodeling mutations identified
More than one-fifth of all human cancers harbor mutations in one of the members of the BAF chromatin remodeling complex. Deep biochemical and epigenomic characterization of a cell line panel comprehensively representing all these mutations enabled researchers at the CeMM Research Center for Molecule Medicine of the Austrian Academy of Sciences to identify new approaches to target BAF mutant cancers. The study describing these findings has now…
Nature podcast with CeMM PI Georg Winter
On 27 June 2019, the ceremony for the Eppendorf Award took place at the EMBL Advanced Training Centre in Heidelberg. The laudation honoring Georg’s achievements was held by Award Jury Chairman Reinhard Jahn, Director of the Max Planck Institute for Biophysical Chemistry, Göttingen. Georg received the € 20.000 prize for his pioneering work developing a method for targeting specific proteins for degradation using heterobifunctional chemical…
An unexpected developmental hierarchy in an unusual disease
Langerhans cell histiocytosis (LCH) is a rare disease affecting primarily young children. While LCH may heal by itself without treatment in some patients, others require intensive chemotherapy and suffer from long-term consequences, or may even succumb to the disease. The reasons for these differences in disease severity are poorly understood. In a new study published in Cancer Discovery, researchers from the St. Anna Children’s Cancer Research…
A public statement by numerous European institutes calls for the amendment of the EU's almost 20-year-old GMO legislation
One year after the European Court of Justice (ECJ) ruling on genome editing: Scientists call on EU politicians to amend legislation to secure our food supply and promote sustainable agriculture. On Thursday, July 25th, 2019, numerous renowned European scientists appealed to the EU to simplify the use of new precision breeding methods to improve crops. This should enable the sustainable development of agriculture and food production in the face…
