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Sylvia Knapp

The innate immune response to bacterial infections

Publications

2016

Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice.

Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S.
Eur J Immunol. 2016 Sep;46(9):2175-86. doi: 10.1002/eji.201546201.
2016

Expanding the Interactome of the Noncanonical NF-_B Signaling Pathway.

Willmann KL, Sacco R, Martins R, Garncarz W, Krolo A, Knapp S, Bennett KL, Boztug K.
J Proteome Res. 2016 Sep 2;15(9):2900-9. doi: 10.1021/acs.jproteome.5b01004.
2016

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S.
Nat Immunol. 2016 Oct 31. doi: 10.1038/ni.3590.
2016

IgE and mast cells in host defense against parasites and venoms.

Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ.
Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Review.
2016

Neutrophils are not required for resolution of acute gouty arthritis in mice.

Reber LL, Gaudenzio N, Starkl P, Galli SJ.
Nat Med. 2016 Dec 6;22(12):1382-1384. doi: 10.1038/nm.4216.
2016

A TNFRSF14-Fc_RI-mast cell pathway contributes to development of multiple features of asthma pathology in mice.

Sibilano R, Gaudenzio N, DeGorter MK, Reber LL, Hernandez JD, Starkl PM, Zurek OW, Tsai M, Zahner S, Montgomery SB, Roers A, Kronenberg M, Yu M, Galli SJ.
Nat Commun. 2016 Dec 16;7:13696. doi: 10.1038/ncomms13696.
2016

Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways.

Kral JB, Kuttke M, Schrottmaier WC, Birnecker B, Warszawska J, Wernig C, Paar H, Salzmann M, Sahin E, Brunner JS, Österreicher C, Knapp S, Assinger A, Schabbauer G.
Sci Rep. 2016 Mar 14;6:23034. doi: 10.1038/srep23034.
2016

Pentraxin-3 levels in graft-versus-host disease during allogeneic hematopoietic stem cell transplantation.

Doehn JM, Winkler A, Kuzmina Z, Hladik A, Greinix H, Knapp S, Robak O.
Exp Hematol. 2016 Jul 9. pii: S0301-472X(16)30460-X.
2015

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity.

Heinz LX, Baumann CL, Köberlin MS, Snijder B, Gawish R, Shui G, Sharif O, Aspalter IM, Müller AC, Kandasamy RK, Breitwieser FP, Pichlmair A, Bruckner M, Rebsamen M, Blüml S, Karonitsch T, Fauster A, Colinge J, Bennett KL, Knapp S, Wenk MR, Superti-Furga G.
Cell Rep. 2015 Jun 30;11(12):1919-28. doi: 10.1016/j.celrep.2015.05.006.