Publications
2016
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Sdelci S,
Lardeau CH,
Tallant C,
Klepsch F,
Klaiber B,
Bennett J,
Rathert P,
Schuster M,
Penz T,
Fedorov O,
Superti-Furga G,
Bock C,
Zuber J,
Huber KV,
Knapp S,
Müller S,
Kubicek S.
Nat Chem Biol. 2016 May 9. doi: 10.1038/nchembio.2080.
2016
Crystal Structure of the Acid Sphingomyelinase-Like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity.
Gorelik A,
Heinz LX,
Illes K,
Superti-Furga G,
Nagar B.
J Biol Chem. 2016 Sep 28. pii: jbc.M116.755801.
2016
NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors.
Byrgazov K,
Kastner R,
Gorna M,
Hoermann G,
Koenig M,
Lucini CB,
Ulreich R,
Benesch M,
Strenger V,
Lackner H,
Schwinger W,
Sovinz P,
Haas OA,
van den Heuvel-Eibrink M,
Niemeyer CM,
Hantschel O,
Valent P,
Superti-Furga G,
Urban C,
Dworzak MN,
Lion T.
Leukemia. 2016 Oct 7. doi: 10.1038/leu.2016.250.
2016
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.
Martins R,
Maier J,
Gorki AD,
Huber KV,
Sharif O,
Starkl P,
Saluzzo S,
Quattrone F,
Gawish R,
Lakovits K,
Aichinger MC,
Radic-Sarikas B,
Lardeau CH,
Hladik A,
Korosec A,
Brown M,
Vaahtomeri K,
Duggan M,
Kerjaschki D,
Esterbauer H,
Colinge J,
Eisenbarth SC,
Decker T,
Bennett KL,
Kubicek S,
Sixt M,
Superti-Furga G,
Knapp S.
Nat Immunol. 2016 Oct 31. doi: 10.1038/ni.3590.
2016
Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.
Matsumoto Y,
La Rose J,
Kent OA,
Wagner MJ,
Narimatsu M,
Levy AD,
Omar MH,
Tong J,
Krieger JR,
Riggs E,
Storozhuk Y,
Pasquale J,
Ventura M,
Yeganeh B,
Post M,
Moran MF,
Grynpas MD,
Wrana JL,
Superti-Furga G,
Koleske AJ,
Pendergast AM,
Rottapel R.
J Clin Invest. 2016 Dec 1;126(12):4482-4496. doi: 10.1172/JCI87802.
2016
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
Peter B,
Winter GE,
Blatt K,
Bennett KL,
Stefanzl G,
Rix U,
Eisenwort G,
Hadzijusufovic E,
Gridling M,
Dutreix C,
Hoermann G,
Schwaab J,
Radia D,
Roesel J,
Manley PW,
Reiter A,
Superti-Furga G,
Valent P.
Leukemia. 2016 Feb;30(2):464-72. doi: 10.1038/leu.2015.242.
2016
NANS-mediated synthesis of sialic acid is required for brain and skeletal development.
van Karnebeek CD,
Bonafé L,
Wen XY,
Tarailo-Graovac M,
Balzano S,
Royer-Bertrand B,
Ashikov A,
Garavelli L,
Mammi I,
Turolla L,
Breen C,
Donnai D,
Cormier V,
Heron D,
Nishimura G,
Uchikawa S,
Campos-Xavier B,
Rossi A,
Hennet T,
Brand-Arzamendi K,
Rozmus J,
Harshman K,
Stevenson BJ,
Girardi E,
Superti-Furga G,
Dewan T,
Collingridge A,
Halparin J,
Ross CJ,
Van Allen MI,
Rossi A,
Engelke UF,
Kluijtmans LA,
van der Heeft E,
Renkema H,
de Brouwer A,
Huijben K,
Zijlstra F,
Heisse T,
Boltje T,
Wasserman WW,
Rivolta C,
Unger S,
Lefeber DJ,
Wevers RA,
Superti-Furga A.
Nat Genet. 2016 May 23. doi: 10.1038/ng.3578.
2016
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.
Tortola L,
Nitsch R,
Bertrand MJ,
Kogler M,
Redouane Y,
Kozieradzki I,
Uribesalgo I,
Fennell LM,
Daugaard M,
Klug H,
Wirnsberger G,
Wimmer R,
Perlot T,
Sarao R,
Rao S,
Hanada T,
Takahashi N,
Kernbauer E,
Demiröz D,
Superti-Furga G,
Decker T,
Pichler A,
Ikeda F,
Kroemer G,
Vandenabeele P,
Sorensen PH,
Penninger JM.
Cell Rep. 2016 May 17;15(7):1481-92. doi: 10.1016/j.celrep.2016.04.032. Epub 2016 May 5.
2016
Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.
Pathria G,
Garg B,
Borgdorff V,
Garg K,
Wagner C,
Superti-Furga G,
Wagner SN.
Cell Death Dis. 2016 Mar 10;7:e2135. doi: 10.1038/cddis.2015.369.
2016
Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.
Müller AC,
Giambruno R,
Weißer J,
Májek P,
Hofer A,
Bigenzahn JW,
Superti-Furga G,
Jessen HJ,
Bennett KL.
Sci Rep. 2016 Jun 27;6:28107. doi: 10.1038/srep28107.
