Publications
2025
Stepwise ATP translocation into the endoplasmic reticulum by human SLC35B1
Ashutosh Gulati,
Do-Hwan Ahn,
Albert Suades,
Yurie Hult,
Gernot Wolf,
So Iwata,
Giulio Superti-Furga,
Norimichi Nomura,
David Drew.
Nature. 2025 May 21. doi: 10.1038/s41586-025-09069-w. Online ahead of print.
2025
Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12
Selina Troester,
Thomas Eder,
Nadja Wukowits,
Martin Piontek,
Pablo Fernández-Pernas,
Johannes Schmoellerl,
Ben Haladik,
Gabriele Manhart,
Melanie Allram,
Margarita Maurer-Granofszky,
Nastassja Scheidegger,
Karin Nebral,
Giulio Superti-Furga,
Roland Meisel,
Beat Bornhauser,
Peter Valent,
Michael N Dworzak,
Johannes Zuber,
Kaan Boztug,
Florian Grebien.
Nat Commun. 2025 May 19;16(1):4656. doi: 10.1038/s41467-025-59930-9.
2025
Data- and knowledge-derived functional landscape of human solute carriers
Ulrich Goldmann,
Tabea Wiedmer,
Andrea Garofoli,
Vitaly Sedlyarov,
Manuel Bichler,
Ben Haladik,
Gernot Wolf,
Eirini Christodoulaki,
Alvaro Ingles-Prieto,
Evandro Ferrada,
Fabian Frommelt,
Shao Thing Teoh,
Philipp Leippe,
Gabriel Onea,
Martin Pfeifer,
Mariah Kohlbrenner,
Lena Chang,
Paul Selzer,
Jürgen Reinhardt,
Daniela Digles,
Gerhard F Ecker,
Tanja Osthushenrich,
Aidan MacNamara,
Anders Malarstig,
David Hepworth,
Giulio Superti-Furga.
Mol Syst Biol. 2025 Jun;21(6):599-631. doi: 10.1038/s44320-025-00108-2. Epub 2025 May 12.
2025
Metabolic mapping of the human solute carrier superfamily
Tabea Wiedmer,
Shao Thing Teoh,
Eirini Christodoulaki,
Gernot Wolf,
Chengzhe Tian,
Vitaly Sedlyarov,
Abigail Jarret,
Philipp Leippe,
Fabian Frommelt,
Alvaro Ingles-Prieto,
Sabrina Lindinger,
Barbara M G Barbosa,
Svenja Onstein,
Christoph Klimek,
Julio Garcia,
Iciar Serrano,
Daniela Reil,
Diana Santacruz,
Mary Piotrowski,
Stephen Noell,
Christoph Bueschl,
Huanyu Li,
Gamma Chi,
Stefan Mereiter,
Tiago Oliveira,
Josef M Penninger,
David B Sauer,
Claire M Steppan,
Coralie Viollet,
Kristaps Klavins,
J Thomas Hannich,
Ulrich Goldmann,
Giulio Superti-Furga.
Mol Syst Biol. 2025 Jun;21(6):560-598. doi: 10.1038/s44320-025-00106-4. Epub 2025 May 12.
2025
The genetic interaction map of the human solute carrier superfamily
Gernot Wolf,
Philipp Leippe,
Svenja Onstein,
Ulrich Goldmann,
Fabian Frommelt,
Shao Thing Teoh,
Enrico Girardi,
Tabea Wiedmer,
Giulio Superti-Furga.
Mol Syst Biol. 2025 Jun;21(6):531-559. doi: 10.1038/s44320-025-00105-5. Epub 2025 May 12.
2025
The solute carrier superfamily interactome
Fabian Frommelt,
Rene Ladurner,
Ulrich Goldmann,
Gernot Wolf,
Alvaro Ingles-Prieto,
Eva Lineiro-Retes,
Zuzana Gelová,
Ann-Katrin Hopp,
Eirini Christodoulaki,
Shao Thing Teoh,
Philipp Leippe,
Brianda L Santini,
Manuele Rebsamen,
Sabrina Lindinger,
Iciar Serrano,
Svenja Onstein,
Christoph Klimek,
Barbara Barbosa,
Anastasiia Pantielieieva,
Vojtech Dvorak,
Thomas J Hannich,
Julian Schoenbett,
Gilles Sansig,
Tamara A M Mocking,
Jasper F Ooms,
Adriaan P IJzerman,
Laura H Heitman,
Peter Sykacek,
Juergen Reinhardt,
André C Müller,
Tabea Wiedmer,
Giulio Superti-Furga.
Mol Syst Biol. 2025 Jun;21(6):632-675. doi: 10.1038/s44320-025-00109-1. Epub 2025 May 12.
2025
Human genetic variants in SLC39A8 impact uptake and steady-state metal levels within the cell
Wen-An Wang,
Andrea Garofoli,
Evandro Ferrada,
Christoph Klimek,
Barbara Steurer,
Alvaro Ingles-Prieto,
Tanja Osthushenrich,
Aidan MacNamara,
Anders Malarstig,
Tabea Wiedmer,
Giulio Superti-Furga.
Life Sci Alliance. 2025 Jan 30;8(4):e202403028. doi: 10.26508/lsa.202403028. Print 2025 Apr.
2025
Transport and inhibition of the sphingosine-1-phosphate exporter SPNS2
Huanyu Z Li,
Ashley C W Pike,
Yung-Ning Chang,
Dheeraj Prakaash,
Zuzana Gelova,
Josefina Stanka,
Christophe Moreau,
Hannah C Scott,
Frank Wunder,
Gernot Wolf,
Andreea Scacioc,
Gavin McKinley,
Helena Batoulis,
Shubhashish Mukhopadhyay,
Andrea Garofoli,
Adán Pinto-Fernández,
Benedikt M Kessler,
Nicola A Burgess-Brown,
Saša Štefanić,
Tabea Wiedmer,
Katharina L Dürr,
Vera Puetter,
Alexander Ehrmann,
Syma Khalid,
Alvaro Ingles-Prieto,
Giulio Superti-Furga,
David B Sauer.
Nat Commun. 2025 Jan 16;16(1):721. doi: 10.1038/s41467-025-55942-7.
2025
The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
Gernot Wolf,
Conner Craigon,
Shao Thing Teoh,
Patrick Essletzbichler,
Svenja Onstein,
Diane Cassidy,
Esther C H Uijttewaal,
Vojtech Dvorak,
Yuting Cao,
Ariel Bensimon,
Ulrich Elling,
Alessio Ciulli,
Giulio Superti-Furga.
Cell Chem Biol. 2025 Feb 20;32(2):291-306.e6. doi: 10.1016/j.chembiol.2024.11.009. Epub 2025 Jan 3.
2024
Ex vivo imaging-based high content phenotyping of patients with rheumatoid arthritis
Felix Kartnig,
Michael Bonelli,
Ulrich Goldmann,
Noemi Mészáros,
Nikolaus Krall,
Daniel Aletaha,
Leonhard X Heinz,
Giulio Superti-Furga.
EBioMedicine. 2025 Jan;111:105522. doi: 10.1016/j.ebiom.2024.105522. Epub 2024 Dec 26.
