An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis

Nelson M LaMarche, Samarth Hegde, Matthew D Park, Barbara B Maier, Leanna Troncoso, Jessica Le Berichel, Pauline Hamon, Meriem Belabed, Raphaël Mattiuz, Clotilde Hennequin, Theodore Chin, Amanda M Reid, Iván Reyes-Torres, Erika Nemeth, Ruiyuan Zhang, Oakley C Olson, Deborah B Doroshow, Nicholas C Rohs, Jorge E Gomez, Rajwanth Veluswamy, Nicole Hall, Nicholas Venturini, Florent Ginhoux, Zhaoyuan Liu, Mark Buckup, Igor Figueiredo, Vladimir Roudko, Kensuke Miyake, Hajime Karasuyama, Edgar Gonzalez-Kozlova, Sacha Gnjatic, Emmanuelle Passegué, Seunghee Kim-Schulze, Brian D Brown, Fred R Hirsch, Brian S Kim, Thomas U Marron, Miriam Merad.
Nature. 2024 Jan;625(7993):166-174. doi: 10.1038/s41586-023-06797-9. Epub 2023 Dec 6.
Abstract: https://pubmed.ncbi.nlm.nih.gov/38057662/

TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer

Matthew D Park, Ivan Reyes-Torres, Jessica LeBerichel, Pauline Hamon, Nelson M LaMarche, Samarth Hegde, Meriem Belabed, Leanna Troncoso, John A Grout, Assaf Magen, Etienne Humblin, Achuth Nair, Martina Molgora, Jinchao Hou, Jenna H Newman, Adam M Farkas, Andrew M Leader, Travis Dawson, Darwin D'Souza, Steven Hamel, Alfonso Rodriguez Sanchez-Paulete, Barbara Maier, Nina Bhardwaj, Jerome C Martin, Alice O Kamphorst, Ephraim Kenigsberg, Maria Casanova-Acebes, Amir Horowitz, Brian D Brown, Lucas Ferrari De Andrade, Marco Colonna, Thomas U Marron, Miriam Merad.
Nat Immunol. 2023 May;24(5):792-801. doi: 10.1038/s41590-023-01475-4. Epub 2023 Apr 20.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37081148/

A progressive T cell exhaustion program mapped across tissues in patients with lung cancer on immune checkpoint blockade

Carolina Mangana, Barbara B Maier.
Cancer Cell. 2023 Apr 10;41(4):653-655. doi: 10.1016/j.ccell.2023.02.020. Epub 2023 Mar 30.
Abstract: https://pubmed.ncbi.nlm.nih.gov/37001525/

Macrophage and monocyte subsets as new therapeutic targets in cancer immunotherapy

B Fendl, A S Berghoff, M Preusser, B Maier.
ESMO Open. 2023 Feb;8(1):100776. doi: 10.1016/j.esmoop.2022.100776. Epub 2023 Feb 1.
Abstract: https://pubmed.ncbi.nlm.nih.gov/36731326/