Publications
2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.
Schischlik F,
Jäger R,
Rosebrock F,
Hug E,
Schuster M,
Holly R,
Fuchs E,Milosevic Feenstra JD,
Bogner E,
Gisslinger B,
Schalling M,
Rumi E,
Pietra D,Fischer G,
Faé I,
Vulliard L,
Menche J,
Haferlach T,
Meggendorfer M,
Stengel A,Bock C,
Cazzola M,
Gisslinger H,
Kralovics R.
Blood. 2019 Jul 11;134(2):199-210. doi: 10.1182/blood.2019000519. Epub2019 May 7.
2019
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation.
Mayor-Ruiz C,
Jaeger MG,
Bauer S,
Brand M,
Sin C,
Hanzl A,
Mueller AC,
Menche J,
Winter GE.
Mol Cell. 2019 Aug 22;75(4):849-858.e8. doi: 10.1016/j.molcel.2019.07.013.
2019
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.
Schick S,
Rendeiro AF,
Runggatscher K,
Ringler A,
Boidol B,
Hinkel M,
Májek P,
Vulliard L,
Penz T,
Parapatics K,
Schmidl C,
Menche J,
Boehmelt G,
Petronczki M,
Müller AC, Bock C,
Kubicek S.
Nat Genet. 2019;51(9):1399–1410. doi:10.1038/s41588-019-0477-9
2018
Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module.
Sharma A,
Kitsak M,
Cho MH,
Ameli A,
Zhou X,
Jiang Z,
Crapo JD,
Beaty TH,
Menche J,
Bakke PS,
Santolini M,
Silverman EK.
Sci Rep. 2018 Sep 27;8(1):14439. doi: 10.1038/s41598-018-32173-z.
2018
Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
Sharma A,
Halu A,
Decano JL,
Padi M,
Liu YY,
Prasad RB,
Fadista J,
Santolini M,
Menche J,
Weiss ST,
Vidal M,
Silverman EK,
Aikawa M,
Barabási AL,
Groop L,
Loscalzo J.
NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018.
2018
Non-classical monocytes as mediators of tissue destruction in arthritis.
Puchner A,
Saferding V,
Bonelli M,
Mikami Y,
Hofmann M,
Brunner JS,
Caldera M,
Goncalves-Alves E,
Binder NB,
Fischer A,
Simader E,
Steiner CW,
Leiss H,
Hayer S,
Niederreiter B,
Karonitsch T,
Koenders MI,
Podesser BK,
O'Shea JJ,
Menche J,
Smolen JS,
Redlich K,
Blüml S.
Ann Rheum Dis. 2018 Oct;77(10):1490-1497. doi: 10.1136/annrheumdis-2018-213250. Epub 2018 Jun 29.
2018
Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.
Aguirre-Plans J,
Piñero J,
Menche J,
Sanz F,
Furlong LI,
Schmidt HHHW,
Oliva B,
Guney E.
Pharmaceuticals (Basel). 2018 Jun 22;11(3). pii: E61. doi: 10.3390/ph11030061.
2018
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.
Velimezi G,
Robinson-Garcia L,
Muñoz-Martínez F,
Wiegant WW,
Ferreira da Silva J,
Owusu M,
Moder M,
Wiedner M,
Rosenthal SB,
Fisch KM,
Moffat J,
Menche J,
van Attikum H,
Jackson SP,
Loizou JI.
Nat Commun. 2018 Jun 11;9(1):2280. doi: 10.1038/s41467-018-04649-z.
2017
Interactome-based approaches to human disease.
M Caldera*,
P Buphamalai*,
F Müller,
J Menche.
Current Opinions in Systems Biology 3:88; 2017.
2017
Integrating personalized gene expression profiles into predictive disease-associated gene pool.
J Menche*,
E Guney*,
A.
npj Systems Biology & Applications 3:10; 2017. doi:10.1038/s41540-017-0009-0
