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Andreas Bergthaler

Andreas Bergthaler

Systemic Immunometabolism in Viral Infection and Advanced Pathogen Surveillance on the Population Level

2021

Slow viral propagation during initial phase of infection leads to viral persistence in mice.

Xu HC, Wang R, Shinde PV, Walotka L, Huang A, Poschmann G, Huang J, Liu W, Stühler K, Schaal H, Bergthaler A, Pandyra AA, Hardt C, Lang KS, Lang PA.
Commun Biol. 2021 Apr 29;4(1):508. doi: 10.1038/s42003-021-02028-x.
2021

Characterization of CD8 T Cell-Mediated Mutations in the Immunodominant Epitope GP33-41 of Lymphocytic Choriomeningitis Virus

Smyth M, Khamina K, Popa A, Gudipati V, Agerer B, Lercher A, Kosack L, Endler L, Baazim H, Viczenczova C, Huppa JB, Bergthaler A.
Front Immunol. 2021 Jun 14;12:638485. doi: 10.3389/fimmu.2021.638485. eCollection 2021.
2020

Selective Mediator dependence of cell-type-specifying transcription.

Jaeger MG, Schwalb B, Mackowiak SD, Velychko T, Hanzl A, Imrichova H, Brand M, Agerer B, Chorn S, Nabet B, Ferguson FM, Müller AC, Bergthaler A, Gray NS, Bradner JE, Bock C, Hnisz D, Cramer P, Winter GE.
Nat Genet. 2020 Jul;52(7):719-727. doi: 10.1038/s41588-020-0635-0. Epub 2020 Jun 1.
2020

Structural cells are key regulators of organ-specific immune responses.

Krausgruber T, Fortelny N, Fife-Gernedl V, Senekowitsch M, Schuster LC, Lercher A, Nemc A, Schmidl C, Rendeiro AF, Bergthaler A, Bock C.
Nature. 2020 Jul;583(7815):296-302. doi: 10.1038/s41586-020-2424-4. Epub 2020 Jul 1.
2020

Tumor-Associated Neutrophils Dampen Adaptive Immunity and Promote Cutaneous Squamous Cell Carcinoma Development.

Khou S, Popa A, Luci C, Bihl F, Meghraoui-Kheddar A, Bourdely P, Salavagione E, Cosson E, Rubod A, Cazareth J, Barbry P, Mari B, Rezzonico R, Anjuère F, Braud VM.
Cancers (Basel). 2020 Jul 10;12(7):1860. doi: 10.3390/cancers12071860.
2020

100 days of solitude: The spring of COVID-19 through the eyes of 15 young virologists of the INITIATE program.

Keszei Z, Vendrell XM, Soultsioti M, Molina PR, Wirth L, Weiss H, Alexandridi M, Aloise C, Susma B, Guy C, Loverre A, Martinez SM, Mazej J, Spahn A, Sularea M, Hiscott J, Hoogen BVD.
Virus Res. 2020 Oct 2;287:198093. doi: 10.1016/j.virusres.2020.198093. Epub 2020 Jul 28.
2020

Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska- Curie innovative training network.

van den Hoogen B, Santoni A, Sciumé G, Bowie A, O'Farrelly C, O'Neill L, Anthonsen M, Pardali K, Young S, Bergthaler A, Manel N, Zahn R, Kikkert M, Snijder E, van Kuppeveld F, Fouchier R, Hiscott J.
Virus Res. 2020 Oct 2;287:198094. doi: 10.1016/j.virusres.2020.198094. Epub 2020 Jul 28.
2020

Emergence of coronavirus disease 2019 (COVID-19) in Austria.

Kreidl P, Schmid D, Maritschnik S, Richter L, Borena W, Genger JW, Popa A, Penz T, Bock C, Bergthaler A, Allerberger F.
Wien Klin Wochenschr. 2020 Nov;132(21-22):645-652. doi: 10.1007/s00508-020-01723-9. Epub 2020 Aug 20.
2020

Human recombinant soluble ACE2 in severe COVID-19.

Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM.
Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Erratum in: Lancet Respir Med. 2020 Nov;8(11):e78.
2020

Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis.

Lercher A, Popa AM, Viczenczova C, Kosack L, Klavins K, Agerer B, Opitz CA, Lanz TV, Platten M, Bergthaler A.
PLoS Pathog. 2020 Oct 12;16(10):e1008973. doi: 10.1371/journal.ppat.1008973.