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Year
Paper
2021
Rizzotto D, Englmaier L, Villunger A. At a Crossroads to Cancer: How p53-Induced Cell Fate Decisions Secure Genome Integrity. Int J Mol Sci. 2021 Oct 8;22(19):10883. doi: 10.3390/ijms221910883.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34639222/
2021
Pezzè L, Meškytė EM, Forcato M, Pontalti S, Badowska KA, Rizzotto D, Skvortsova II, Bicciato S, Ciribilli Y. ETV7 regulates breast cancer stem-like cell features by repressing IFN-response genes. Cell Death Dis. 2021 Jul 27;12(8):742. doi: 10.1038/s41419-021-04005-y.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34315857/
2021
Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ. Correction: Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ. 2021 Jul 23. doi: 10.1038/s41418-021-00831-x. Online ahead of print.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34302122/
2021
Sladky VC, Eichin F, Reiberger T, Villunger A. Polyploidy control in hepatic health and disease. J Hepatol. 2021 Nov;75(5):1177-1191. doi: 10.1016/j.jhep.2021.06.030. Epub 2021 Jul 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34228992/
2022
Hutter K, Lindner SE, Kurschat C, Rülicke T, Villunger A, Herzog S. The miR-26 family regulates early B cell development and transformation. Life Sci Alliance. 2022 Apr 22;5(8):e202101303. doi: 10.26508/lsa.202101303. Print 2022 Aug.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35459737/
2022
Weiler ES, Szabo TG, Garcia-Carpio I, Villunger A. PIDD1 in cell cycle control, sterile inflammation and cell death. Biochem Soc Trans. 2022 Apr 29;50(2):813-824. doi: 10.1042/BST20211186.
Abstract: https://pubmed.ncbi.nlm.nih.gov/35343572/
2022
Flores-Romero H, Hohorst L, John M, Albert MC, King LE, Beckmann L, Szabo T, Hertlein V, Luo X, Villunger A, Frenzel LP, Kashkar H, Garcia-Saez AJ. BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. EMBO J. 2022 Dec 17;41(2):e108690. doi: 10.15252/embj.2021108690. Epub 2021 Dec 21.
Abstract: https://pubmed.ncbi.nlm.nih.gov/34931711/
2021
Hutter K, Rülicke T, Drach M, Andersen L, Villunger A, Herzog S. Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis. FEBS J. 2021 Mar;288(5):1533-1545. doi: 10.1111/febs.15493. Epub 2020 Aug 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32705746/
2021
Rizzotto D, Villunger A. P53 clears aneuploid cells by entosis. Cell Death Differ. 2021 Feb;28(2):818-820. doi: 10.1038/s41418-020-00659-x. Epub 2020 Nov 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33149274/
2021
Burigotto M, Mattivi A, Migliorati D, Magnani G, Valentini C, Roccuzzo M, Offterdinger M, Pizzato M, Schmidt A, Villunger A, Maffini S, Fava LL. Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26. EMBO J. 2021 Feb 15;40(4):e104844. doi: 10.15252/embj.2020104844. Epub 2020 Dec 22.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33350486/
2021
Sheikh TI, Vasli N, Pastore S, Kharizi K, Harripaul R, Fattahi Z, Pande S, Naeem F, Hussain A, Mir A, Islam O, Girisha KM, Irfan M, Ayub M, Schwarzer C, Najmabadi H, Shukla A, Sladky VC, Braun VZ, Garcia-Carpio I, Villunger A, Vincent JB. Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability. Transl Psychiatry. 2021 Jan 5;11(1):1. doi: 10.1038/s41398-020-01158-w.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33414379/
2020
Haschka MD, Karbon G, Soratroi C, O'Neill KL, Luo X, Villunger A. MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. Cell Death Differ. 2020 Aug;27(8):2297-2312. doi: 10.1038/s41418-020-0503-6. Epub 2020 Feb 3.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32015503/
2020
Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ. Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ. 2020 Sep;27(9):2620-2634. doi: 10.1038/s41418-020-0527-y. Epub 2020 Mar 19.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32203171/
2020
Sladky VC, Villunger A. Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation. Cell Death Differ. 2020 Jul;27(7):2037-2047. doi: 10.1038/s41418-020-0556-6. Epub 2020 May 15.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32415279/
2020
Connolly P, Garcia-Carpio I, Villunger A. Cell-Cycle Cross Talk with Caspases and Their Substrates. Cold Spring Harb Perspect Biol. 2020 Jun 1;12(6):a036475. doi: 10.1101/cshperspect.a036475.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31727679/
2020
Hutter K, Lohmüller M, Jukic A, Eichin F, Avci S, Labi V, Szabo TG, Hoser SM, Hüttenhofer A, Villunger A, Herzog S. SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts. Mol Cell. 2020 Jun 4;78(5):876-889.e6. doi: 10.1016/j.molcel.2020.05.011.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32502422/
2020
Hutter K, Rülicke T, Drach M, Andersen L, Villunger A, Herzog S. Differential roles of miR-15a/16-1 and miR-497/195 clusters in immune cell development and homeostasis. FEBS J. 2021 Mar;288(5):1533-1545. doi: 10.1111/febs.15493. Epub 2020 Aug 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/32705746/
2020
Rizzotto D, Villunger A. P53 clears aneuploid cells by entosis. Cell Death Differ. 2021 Feb;28(2):818-820. doi: 10.1038/s41418-020-00659-x. Epub 2020 Nov 4.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33149274/
2020
Sladky VC, Knapp K, Szabo TG, Braun VZ, Bongiovanni L, van den Bos H, Spierings DC, Westendorp B, Curinha A, Stojakovic T, Scharnagl H, Timelthaler G, Tsuchia K, Pinter M, Semmler G, Foijer F, de Bruin A, Reiberger T, Rohr-Udilova N, Villunger A. PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis. EMBO Rep. 2020 Dec 3;21(12):e50893. doi: 10.15252/embr.202050893. Epub 2020 Nov 23.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33225610/
2020
Burigotto M, Mattivi A, Migliorati D, Magnani G, Valentini C, Roccuzzo M, Offterdinger M, Pizzato M, Schmidt A, Villunger A, Maffini S, Fava LL. Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26. EMBO J. 2021 Feb 15;40(4):e104844. doi: 10.15252/embj.2020104844. Epub 2020 Dec 22.
Abstract: https://pubmed.ncbi.nlm.nih.gov/33350486/
2020
Sladky VC, Knapp K, Soratroi C, Heppke J, Eichin F, Rocamora-Reverte L, Szabo TG, Bongiovanni L, Westendorp B, Moreno E, van Liere EA, Bakker B, Spierings DCJ, Wardenaar R, Pereyra D, Starlinger P, Schultze S, Trauner M, Stojakovic T, Scharnagl H, Fava LL, Foijer F, de Bruin A, Villunger A. E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration. Dev Cell. 2020 Feb 10;52(3):335-349.e7. doi: 10.1016/j.devcel.2019.12.016. Epub 2020 Jan 23.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31983631
2019
Connolly P, Garcia-Carpio I, Villunger A. Cell-Cycle Cross Talk with Caspases and Their Substrates. Cold Spring Harb Perspect Biol. 2019 Nov 14. pii: a036475. doi: 10.1101/cshperspect.a036475.
Abstract: https://pubmed.ncbi.nlm.nih.gov/31727679/
2019
Schuler F, Afreen S, Manzl C, Häcker G, Erlacher M, Villunger A. Checkpoint kinase 1 is essential for fetal and adult hematopoiesis. EMBO Rep. 2019 Aug;20(8):e47026. doi: 10.15252/embr.201847026. Epub 2019 Jun 17.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31379128
2019
Schoeler K, Jakic B, Heppke J, Soratroi C, Aufschnaiter A, Hermann-Kleiter N,Villunger A, Labi V. CHK1 dosage in germinal center B cells controls humoral immunity. Cell Death Differ. 2019 Mar 20. doi: 10.1038/s41418-019-0318-5. [Epubahead of print]
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30894677
2019
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A,Rajewsky K, Labi V. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019 May 23. doi:10.1111/febs.14934. [Epub ahead of print]
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/31120187
2019
Rocamora-Reverte L, Tuzlak S, von Raffay L, Tisch M, Fiegl H, Drach M,Reichardt HM, Villunger A, Tischner D, Wiegers GJ. Glucocorticoid Receptor-Deficient Foxp3(+) Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease. Front Immunol. 2019 Mar 18;10:472. doi:10.3389/fimmu.2019.00472. eCollection 2019.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30936873
2019
Asslaber D, Wacht N, Leisch M, Qi Y, Maeding N, Hufnagl C, Jansko B, Zaborsky N, Villunger A, Hartmann TN, Greil R, Egle A. BIRC3 Expression Predicts CLL Progression and Defines Treatment Sensitivity via Enhanced NF-κB Nuclear Translocation. Clin Cancer Res. 2019 Mar 15;25(6):1901-1912. doi:10.1158/1078-0432.CCR-18-1548. Epub 2018 Nov 28.
Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30487125