2025
Advances in Bioprinting to Model Immune-Mediated Skin Diseases
Andrea Ulloa-Fernández,
Marica Markovic,
Julia Fernández-Pérez,
Georg Stary,
Aleksandr Ovsianikov.
Adv Healthc Mater. 2025 Nov 27:e03806. doi: 10.1002/adhm.202503806. Online ahead of print.
2025
Harnessing the E3 ligase SPOP for targeted degradation of the NUP98::KDM5A fusion oncoprotein
Ecem Kirkiz,
Gabriel Kaufmann,
Simone Bergqvist,
Pablo Fernández-Pernas,
Thomas Eder,
Laura Quell,
Melanie Allram,
Gabriele Manhart,
Wencke Walter,
Torsten Haferlach,
Florian Grebien.
Cell Rep. 2025 Dec 23;44(12):116602. doi: 10.1016/j.celrep.2025.116602. Epub 2025 Nov 25.
2025
Inhibitors supercharge kinase turnover through native proteolytic circuits
Natalie S Scholes,
Martino Bertoni,
Arnau Comajuncosa-Creus,
Katharina Kladnik,
Xuefei Guo,
Fabian Frommelt,
Matthias Hinterndorfer,
Hlib Razumkov,
Polina Prokofeva,
Martin P Schwalm,
Florian Born,
Sandra Roehm,
Hana Imrichova,
Brianda L Santini,
Eleonora Barone,
Caroline Schätz,
Miquel Muñoz I Ordoño,
Severin Lechner,
Andrea Rukavina,
Iciar Serrano,
Miriam Abele,
Anna Koren,
Stefan Kubicek,
Stefan Knapp,
Nathanael S Gray,
Giulio Superti-Furga,
Bernhard Kuster,
Yigong Shi,
Patrick Aloy,
Georg E Winter.
Nature. 2025 Nov 26. doi: 10.1038/s41586-025-09763-9. Online ahead of print.
2025
Interleukin-38 is a negative regulator of trained immunity-A retrospective multi-omics study
Lisa U Teufel,
Vasiliki Matzaraki,
Lukas Folkman,
Dennis M de Graaf,
Rob Ter Horst,
Simone J C F M Moorlag,
Jéssica C Dos Santos,
Catharina M Mulders-Manders,
Thomas Krausgruber,
Charles Dinarello,
Mihai G Netea,
Leo A B Joosten,
Rob J W Arts.
iScience. 2025 Oct 14;28(11):113758. doi: 10.1016/j.isci.2025.113758. eCollection 2025 Nov 21.
2025
Long-term outcome of bone marrow transplantation in NIK deficiency: non-redundant role of non-canonical NF-κB signaling in thymic reconstitution and secondary lymphoid organ development
Sevgi Köstel Bal,
Şule Haskoloğlu,
Bernhard Ransmayr,
Selin Sevinç,
Candan İslamoğlu,
Kübra Baskın,
Nazlı Deveci,
Berna Savaş,
Suat Fitoz,
Alphan Küpesiz,
Tanıl Kendirli,
Kaan Boztug,
Figen Doğu,
Kamile Aydan İkincioğulları.
Front Immunol. 2025 Nov 7;16:1682642. doi: 10.3389/fimmu.2025.1682642. eCollection 2025.
2025
Immune cells composition in the skin and subcutaneous adipose tissue of patients with systemic sclerosis
Marija Geroldinger-Simić,
Ana E Aguilar González,
Gerald Exler,
Georg Stary.
J Dtsch Dermatol Ges. 2025 Nov 20. doi: 10.1111/ddg.15864. Online ahead of print.
2025
Author Correction: CD8+ T cells induce cachexia during chronic viral infection
Hatoon Baazim,
Martina Schweiger,
Michael Moschinger,
Haifeng Xu,
Thomas Scherer,
Alexandra Popa,
Suchira Gallage,
Adnan Ali,
Kseniya Khamina,
Lindsay Kosack,
Bojan Vilagos,
Mark Smyth,
Alexander Lercher,
Joachim Friske,
Doron Merkler,
Alan Aderem,
Thomas H Helbich,
Mathias Heikenwälder,
Philipp A Lang,
Rudolf Zechner,
Andreas Bergthaler.
Nat Immunol. 2026 Jan;27(1):166. doi: 10.1038/s41590-025-02369-3.
2025
Multimodal learning enables chat-based exploration of single-cell data
Moritz Schaefer,
Peter Peneder,
Daniel Malzl,
Salvo Danilo Lombardo,
Mihaela Peycheva,
Jake Burton,
Anna Hakobyan,
Varun Sharma,
Thomas Krausgruber,
Celine Sin,
Jörg Menche,
Eleni M Tomazou,
Christoph Bock.
Nat Biotechnol. 2025 Nov 11. doi: 10.1038/s41587-025-02857-9. Online ahead of print.
2025
A non-enzymatic role of Nudix hydrolase 5 in repressing purine de novo synthesis
Tuan-Anh Nguyen,
Jung-Ming G Lin,
Anne-Sophie M C Marques,
Maximilian Fottner,
Ludwig G Bauer,
Andreas Reicher,
Diana Daum,
Lorenzo Scrofani,
Yusi Liu,
Carol Cheng,
Luna D'Angelo L D D,
Juan Sanchez,
Christoph Bueschl,
Nara Marella,
Pisanu Buphamalai,
Florian Traversi,
Maša Bereš,
Herwig P Moll,
Marton Siklos,
Jakob-Wendelin Genger,
Gerald Hofstaetter,
Ludovica Villanti,
Monika Malik,
Christoph Klimek,
Kathrin Runggatscher,
Bettina Guertl,
Jesper S Hansen,
Sarah Dobner,
Olga Babosova,
Tina Becirovic,
Laura P M H de Rooij,
Emilio Casanova,
Anna Koren,
D Sean Froese,
David S Rosenblatt,
Kristaps Klavins,
Andreas Bergthaler,
Jörg Menche,
J Thomas Hannich,
Miriam Abele,
Sara Sdelci,
Kathrin Lang,
Kilian V M Huber,
Stefan Kubicek.
Science. 2025 Dec 11;390(6778):1143-1150. doi: 10.1126/science.adv4257. Epub 2025 Nov 6.
2025
Tyrosine kinase targeting uncovers oncogenic pathway plasticity in Tasmanian devil transmissible cancers
Anna Schönbichler,
Anna Orlova,
Carmen Kreindl,
Lukas Endler,
Richard Wilson,
Lindsay Kosack,
Anna Hofmann,
Csilla Viczenczova,
Jocelyn Darby,
Fettah Erdogan,
Amanda L Patchett,
Anna Koren,
Stefan Kubicek,
Mathias Müller,
Andrew S Flies,
Andreas Bergthaler,
Richard Moriggl.
EMBO J. 2025 Nov 3. doi: 10.1038/s44318-025-00603-0. Online ahead of print.
