Publications
2020
Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis.
Bensimon A,
Pizzagalli MD,
Kartnig F,
Dvorak V,
Essletzbichler P,
Winter GE,
Superti-Furga G.
Cell Chem Biol. 2020 Jun 18;27(6):728-739.e9. doi: 10.1016/j.chembiol.2020.04.003. Epub 2020 May 7.
2020
Caught in the genetic network: a novel regulator of lipid metabolism.
Girardi E,
Superti-Furga G.
Nat Metab. 2020 Jun;2(6):483-484. doi: 10.1038/s42255-020-0218-5.
2020
A substrate-based ontology for human solute carriers.
Meixner E,
Goldmann U,
Sedlyarov V,
Scorzoni S,
Rebsamen M,
Girardi E,
Superti-Furga G.
Mol Syst Biol. 2020 Jul;16(7):e9652. doi: 10.15252/msb.20209652.
2020
eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition.
Wuerth JD,
Habjan M,
Kainulainen M,
Berisha B,
Bertheloot D,
Superti-Furga G,
Pichlmair A,
Weber F.
mBio. 2020 Jul 14;11(4):e00976-20. doi: 10.1128/mBio.00976-20.
2020
A guide to plasma membrane solute carrier proteins.
Pizzagalli MD,
Bensimon A,
Superti-Furga G.
FEBS J. 2021 May;288(9):2784-2835. doi: 10.1111/febs.15531. Epub 2020 Sep 18.
2020
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2.
Popa A,
Genger JW,
Nicholson MD,
Penz T,
Schmid D,
Aberle SW,
Agerer B,
Lercher A,
Endler L,
Colaço H,
Smyth M,
Schuster M,
Grau ML,
Martínez-Jiménez F,
Pich O,
Borena W,
Pawelka E,
Keszei Z,
Senekowitsch M,
Laine J,
Aberle JH,
Redlberger-Fritz M,
Karolyi M,
Zoufaly A,
Maritschnik S,
Borkovec M,
Hufnagl P,
Nairz M,
Weiss G,
Wolfinger MT,
von Laer D,
Superti-Furga G,
Lopez-Bigas N,
Puchhammer-Stöckl E,
Allerberger F,
Michor F,
Bock C,
Bergthaler A.
Sci Transl Med. 2020 Dec 9;12(573):eabe2555. doi: 10.1126/scitranslmed.abe2555. Epub 2020 Nov 23.
2020
Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import.
Girardi E,
Agrimi G,
Goldmann U,
Fiume G,
Lindinger S,
Sedlyarov V,
Srndic I,
Gürtl B,
Agerer B,
Kartnig F,
Scarcia P,
Di Noia MA,
Liñeiro E,
Rebsamen M,
Wiedmer T,
Bergthaler A,
Palmieri L,
Superti-Furga G.
Nat Commun. 2020 Dec 1;11(1):6145. doi: 10.1038/s41467-020-19871-x.
2020
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Heinz LX,
Lee J,
Kapoor U,
Kartnig F,
Sedlyarov V,
Papakostas K,
César- Razquin A,
Essletzbichler P,
Goldmann U,
Stefanovic A,
Bigenzahn JW,
Scorzoni S,
Pizzagalli MD,
Bensimon A,
Müller AC,
King FJ,
Li J,
Girardi E,
Mbow ML,
Whitehurst CE,
Rebsamen M,
Superti-Furga G.
Nature. 2020 May;581(7808):316-322. doi: 10.1038/s41586-020-2282-0. Epub 2020 May 13.
2020
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs.
Girardi E,
César-Razquin A,
Lindinger S,
Papakostas K,
Konecka J,
Hemmerich J,
Kickinger S,
Kartnig F,
Gürtl B,
Klavins K,
Sedlyarov V,
Ingles-Prieto A,
Fiume G,
Koren A,
Lardeau CH,
Kumaran Kandasamy R,
Kubicek S,
Ecker GF,
Superti-Furga G.
Nat Chem Biol. 2020 Apr;16(4):469-478. doi: 10.1038/s41589-020-0483-3. Epub 2020 Mar 9.
2019
The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis.
Mian AA,
Baumann I,
Liebermann M,
Grebien F,
Superti-Furga G,
Ruthardt M,Ottmann OG,
Hantschel O.
Leukemia. 2019 Apr 8. doi:10.1038/s41375-019-0468-y. [Epub ahead of print]
