Publications
2012
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia.
Hantschel O,
Warsch W,
Eckelhart E,
Kaupe I,
Grebien F,
Wagner KU,
Superti-Furga G,
Sexl V.
Nat Chem Biol. 2012 Jan 29;8(3):285-93.
2012
Cell biology: a key driver of therapeutic innovation.
Hantschel O,
Superti-Furga G.
J Cell Biol. 2012 Nov 12;199(4):571-5.
2012
The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL.
Hantschel O,
Grebien F,
Superti-Furga G.
Cancer Res. 2012 Oct 1;72(19):4890-5.
2012
SAMHD1 is a nucleic acid-binding protein that is mislocalised due to Aicardi-Goutières syndrome-associated mutations.
Goncalves A,
Karayel E,
Rice GI,
Bennett KL,
Crow YJ,
Superti-Furga G,
Bürckstümmer T.
Human Mut. 2012 Jul;33(7):1116-22.
2011
An integrated chemical biology approach identifies specific vulnerability of Ewing’s sarcoma to combined inhibition of Aurora kinases A and B.
Winter GE,
Rix U,
Lissat A,
Stukalov A,
Mullner MK,
Bennett KL,
Colinge J,
Nijman SM,
Kubicek S,
Kovar H,
Kontny U,
Superti-Furga G.
Mol Cancer Ther. 2011 Oct;10(10):1846-56.
2011
IFIT1 is an antiviral protein that recognizes 5’-triphosphate RNA.
Pichlmair A,
Lassnig C,
Eberle CA,
Gorna MW,
Baumann CL,
Burkard TR,
Burckstummer T,
Stefanovic A,
Krieger S,
Bennett KL,
Rulicke T,
Weber F,
Colinge J,
Muller M,
Superti-Furga G.
Nat Immunol. 2011 Jul;12(7):624-30.
2011
After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders.
Huber K,
Superti-Furga G.
Bioorg Med Chem. 2011 Jun 15;19(12):3616-24.
2011
Targeting allosteric regulatory modules in oncoproteins: “drugging the undruggable”.
Hantschel O,
Grebien F,
Superti-Furga G.
Oncotarget. 2011 Nov;2(11):828-9.
2011
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
Grebien F,
Hantschel O,
Wojcik J,
Kaupe I,
Kovacic B,
Wyrzucki AM,
Gish GD,
Cerny-Reiterer S,
Koide A,
Beug H,
Pawson T,
Valent P,
Koide S,
Superti-Furga G.
Cell. 2011 Oct 14;147(2):306-19.
2011
Functional dissection of the TBK1 molecular network.
Goncalves A,
Burckstummer T,
Dixit E,
Scheicher R,
Gorna MW,
Karayel E,
Sugar C,
Stukalov A,
Berg T,
Kralovics R,
Planyavsky M,
Bennett KL,
Colinge J,
Superti-Furga G.
PLoS One. 2011;6(9):e23971.
