Publications
2021
RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.
Paolino M,
Koglgruber R,
Cronin SJF,
Uribesalgo I,
Rauscher E,
Harreiter J,
Schuster M,
Bancher-Todesca D,
Pranjic B,
Novatchkova M,
Fededa JP,
White AJ,
Sigl V,
Dekan S,
Penz T,
Bock C,
Kenner L,
Holländer GA,
Anderson G,
Kautzky-Willer A,
Penninger JM.
Nature. 2021 Jan;589(7842):442-447. doi: 10.1038/s41586-020-03071-0. Epub 2020 Dec 23.
2021
The Organoid Cell Atlas.
Bock C,
Boutros M,
Camp JG,
Clarke L,
Clevers H,
Knoblich JA,
Liberali P,
Regev A,
Rios AC,
Stegle O,
Stunnenberg HG,
Teichmann SA,
Treutlein B,
Vries RGJ; Human Cell Atlas ‘Biological Network’ Organoids.
Nat Biotechnol. 2021 Jan;39(1):13-17. doi: 10.1038/s41587-020-00762-x.
2021
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.
Müller JA,
Groß R,
Conzelmann C,
Krüger J,
Merle U,
Steinhart J,
Weil T,
Koepke L,
Bozzo CP,
Read C,
Fois G,
Eiseler T,
Gehrmann J,
van Vuuren J,
Wessbecher IM,
Frick M,
Costa IG,
Breunig M,
Grüner B,
Peters L,
Schuster M,
Liebau S,
Seufferlein T,
Stenger S,
Stenzinger A,
MacDonald PE,
Kirchhoff F,
Sparrer KMJ,
Walther P,
Lickert H,
Barth TFE,
Wagner M,
Münch J,
Heller S,
Kleger A.
Nat Metab. 2021 Feb;3(2):149-165. doi: 10.1038/s42255-021-00347-1. Epub 2021 Feb 3.
2021
Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements.
Thomas HF,
Kotova E,
Jayaram S,
Pilz A,
Romeike M,
Lackner A,
Penz T,
Bock C,
Leeb M,
Halbritter F,
Wysocka J,
Buecker C.
Mol Cell. 2021 Mar 4;81(5):969-982.e13. doi: 10.1016/j.molcel.2020.12.047. Epub 2021 Jan 21.
2021
Persistence of mature dendritic cells, T(H)2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade.
Bangert C,
Rindler K,
Krausgruber T,
Alkon N,
Thaler FM,
Kurz H,
Ayub T,
Demirtas D,
Fortelny N,
Vorstandlechner V,
Bauer WM,
Quint T,
Mildner M,
Jonak C,
Elbe-Bürger A,
Griss J,
Bock C,
Brunner PM.
Sci Immunol. 2021 Jan 22;6(55):eabe2749. doi: 10.1126/sciimmunol.abe2749.
2021
Acute BAF perturbation causes immediate changes in chromatin accessibility.
Schick S,
Grosche S,
Kohl KE,
Drpic D,
Jaeger MG,
Marella NC,
Imrichova H,
Lin JG,
Hofstätter G,
Schuster M,
Rendeiro AF,
Koren A,
Petronczki M,
Bock C,
Müller AC,
Winter GE,
Kubicek S.
Nat Genet. 2021 Mar;53(3):269-278. doi: 10.1038/s41588-021-00777-3. Epub 2021 Feb 8.
2021
Tumor mutational burden and immune infiltrates in renal cell carcinoma and matched brain metastases.
Steindl A,
Alpar D,
Heller G,
Mair MJ,
Gatterbauer B,
Dieckmann K,
Widhalm G,
Hainfellner JA,
Schmidinger M,
Bock C,
Müllauer L,
Preusser M,
Berghoff AS.
ESMO Open. 2021 Apr;6(2):100057. doi: 10.1016/j.esmoop.2021.100057. Epub 2021 Feb 12.
2021
EZH2 inactivation in RAS-driven myeloid neoplasms hyperactivates RAS-signaling and increases MEK inhibitor sensitivity.
Berg JL,
Perfler B,
Hatzl S,
Uhl B,
Reinisch A,
Pregartner G,
Berghold A,
Penz T,
Schuster M,
Geissler K,
Prokesch A,
Müller-Tidow C,
Hoefler G,
Kashofer K,
Wölfler A,
Sill H,
Caraffini V,
Zebisch A.
Leukemia. 2021 Feb 15. doi: 10.1038/s41375-021-01161-0. Online ahead of print.
2021
Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.
Valent P,
Orfao A,
Kubicek S,
Staber P,
Haferlach T,
Deininger M,
Kollmann K,
Lion T,
Virgolini I,
Winter G,
Hantschel O,
Kenner L,
Zuber J,
Grebien F,
Moriggl R,
Hoermann G,
Hermine O,
Andreeff M,
Bock C,
Mughal T,
Constantinescu SN,
Kralovics R,
Sexl V,
Skoda R,
Superti-Furga G,
Jäger U.
Hemasphere. 2021 Feb 17;5(3):e536. doi: 10.1097/HS9.0000000000000536. eCollection 2021 Mar.
2021
Histone deacetylase 1 controls CD4(+) T cell trafficking in autoinflammatory diseases.
Hamminger P,
Marchetti L,
Preglej T,
Platzer R,
Zhu C,
Kamnev A,
Rica R,
Stolz V,
Sandner L,
Alteneder M,
Kaba E,
Waltenberger D,
Huppa JB,
Trauner M,
Bock C,
Lyck R,
Bauer J,
Dupré L,
Seiser C,
Boucheron N,
Engelhardt B,
Ellmeier W.
J Autoimmun. 2021 May;119:102610. doi: 10.1016/j.jaut.2021.102610. Epub 2021 Feb 20.
