Publications
2023
Decreased platelet activation predicts hepatic decompensation and mortality in patients with cirrhosis
Benedikt S Hofer,
Ksenia Brusilovskaya,
Benedikt Simbrunner,
Lorenz Balcar,
Beate Eichelberger,
Silvia Lee,
Lukas Hartl,
Philipp Schwabl,
Mattias Mandorfer,
Simon Panzer,
Thomas Reiberger,
Thomas Gremmel.
Hepatology. 2023 Dec 27. doi: 10.1097/HEP.0000000000000740. Online ahead of print.
2023
Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome
Benedikt Simbrunner,
Ida Falk Villesen,
Bernhard Scheiner,
Rafael Paternostro,
Philipp Schwabl,
Albert Friedrich Stättermayer,
Rodrig Marculescu,
Matthias Pinter,
Peter Quehenberger,
Michael Trauner,
Morten Karsdal,
Ton Lisman,
Thomas Reiberger,
Diana Julie Leeming,
Mattias Mandorfer.
Hepatol Int. 2023 Dec;17(6):1532-1544. doi: 10.1007/s12072-023-10577-y. Epub 2023 Aug 21.
2023
GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling
Claudia D Fuchs,
Thierry Claudel,
Veronika Mlitz,
Alessandra Riva,
Moritz Menz,
Ksenia Brusilovskaya,
Felix Haller,
Maximilian Baumgartner,
Philipp Königshofer,
Lukas W Unger,
Wilhelm Sjöland,
Hubert Scharnagl,
Tatjana Stojakovic,
Georg Busslinger,
Thomas Reiberger,
Hanns-Ulrich Marschall,
Michael Trauner.
Cell Mol Gastroenterol Hepatol. 2023;16(5):847-856. doi: 10.1016/j.jcmgh.2023.08.003. Epub 2023 Aug 10.
2023
Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis
Benedikt Simbrunner,
Lukas Hartl,
Mathias Jachs,
David J M Bauer,
Bernhard Scheiner,
Benedikt Silvester Hofer,
Albert Friedrich Stättermayer,
Rodrig Marculescu,
Michael Trauner,
Mattias Mandorfer,
Thomas Reiberger.
JHEP Rep. 2023 Feb 24;5(5):100712. doi: 10.1016/j.jhepr.2023.100712. eCollection 2023 May.
2023
Disturbances in sodium and chloride homeostasis predict outcome in stable and critically ill patients with cirrhosis
Georg Semmler,
Bernhard Scheiner,
Lorenz Balcar,
Rafael Paternostro,
Benedikt Simbrunner,
Matthias Pinter,
Michael Trauner,
Marta Bofill Roig,
Elias Laurin Meyer,
Benedikt Silvester Hofer,
Mattias Mandorfer,
David James Pinato,
Christian Zauner,
Thomas Reiberger,
Georg-Christian Funk.
Aliment Pharmacol Ther. 2023 Jul;58(1):71-79. doi: 10.1111/apt.17507. Epub 2023 Apr 4.
2023
Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response
Benedikt Simbrunner,
Esther Caparrós,
Teresa Neuwirth,
Philipp Schwabl,
Philipp Königshofer,
David Bauer,
Rodrig Marculescu,
Michael Trauner,
Bernhard Scheiner,
Georg Stary,
Mattias Mandorfer,
Thomas Reiberger,
Rubén Francés.
Hepatol Int. 2023 Aug;17(4):1045-1056. doi: 10.1007/s12072-023-10496-y. Epub 2023 Mar 7.
2022
Imaging features facilitate diagnosis of porto-sinusoidal vascular disorder
Katharina Lampichler,
Georg Semmler,
Katharina Wöran,
Benedikt Simbrunner,
Mathias Jachs,
Lukas Hartl,
David Josef Maria Bauer,
Lorenz Balcar,
Lukas Burghart,
Michael Trauner,
Dietmar Tamandl,
Ahmed Ba-Ssalamah,
Mattias Mandorfer,
Thomas Reiberger,
Bernhard Scheiner,
Martina Scharitzer.
Eur Radiol. 2023 Feb;33(2):1422-1432. doi: 10.1007/s00330-022-09132-4. Epub 2022 Sep 27.
2022
Assessment of portal hypertension severity using machine learning models in patients with compensated cirrhosis
Jiří Reiniš,
Oleksandr Petrenko,
Benedikt Simbrunner,
Benedikt S Hofer,
Filippo Schepis,
Marco Scoppettuolo,
Dario Saltini,
Federica Indulti,
Tomas Guasconi,
Agustin Albillos,
Luis Téllez,
Càndid Villanueva,
Anna Brujats,
Juan Carlos Garcia-Pagan,
Valeria Perez-Campuzano,
Virginia Hernández-Gea,
Pierre-Emmanuel Rautou,
Lucile Moga,
Thomas Vanwolleghem,
Wilhelmus J Kwanten,
Sven Francque,
Jonel Trebicka,
Wenyi Gu,
Philip G Ferstl,
Lise Lotte Gluud,
Flemming Bendtsen,
Søren Møller,
Stefan Kubicek,
Mattias Mandorfer,
Thomas Reiberger.
J Hepatol. 2023 Feb;78(2):390-400. doi: 10.1016/j.jhep.2022.09.012. Epub 2022 Sep 22.
2022
Systemic inflammation is linked to liver fibrogenesis in patients with advanced chronic liver disease
Benedikt Simbrunner,
Ida Falk Villesen,
Philipp Königshofer,
Bernhard Scheiner,
David Bauer,
Rafael Paternostro,
Philipp Schwabl,
Gerald Timelthaler,
Dariga Ramazanova,
Katharina Wöran,
Judith Stift,
Ernst Eigenbauer,
Albert Friedrich Stättermayer,
Rodrig Marculescu,
Matthias Pinter,
Søren Møller,
Michael Trauner,
Morten Karsdal,
Diana Julie Leeming,
Thomas Reiberger,
Mattias Mandorfer.
Liver Int. 2022 Nov;42(11):2501-2512. doi: 10.1111/liv.15365. Epub 2022 Aug 25.
2022
Angiopoietin 2 levels decrease after HCV-cure and reflect the evolution of portal hypertension
David Bauer,
Karin Kozbial,
Philipp Schwabl,
David Chromy,
Benedikt Simbrunner,
Albert F Stättermayer,
Matthias Pinter,
Petra Steindl-Munda,
Michael Trauner,
Peter Ferenci,
Thomas Reiberger,
Mattias Mandorfer.
Dig Liver Dis. 2022 Sep;54(9):1222-1229. doi: 10.1016/j.dld.2022.02.013. Epub 2022 Apr 3.
