Publications
2026
Blood-based Vienna 3P/5P risk models accurately predict first hepatic decompensation in compensated advanced chronic liver disease
Georg Kramer,
Benedikt Simbrunner,
Mathias Jachs,
Lorenz Balcar,
Benedikt Silvester Hofer,
Nina Dominik,
Lukas Hartl,
Michael Schwarz,
Georg Semmler,
Christian Sebesta,
Paul Thöne,
Sophia Geisselbrecht,
Benjamin Maasoumy,
Eduardo Alvarez,
Martin Sebastian McCoy,
Oleksandr Petrenko,
Jiří Reiniš,
Philipp Schwabl,
Albert F Stättermayer,
Michael Trauner,
Mattias Mandorfer,
Thomas Reiberger.
JHEP Rep. 2025 Oct 17;8(2):101642. doi: 10.1016/j.jhepr.2025.101642. eCollection 2026 Feb.
2025
Editorial: Extracellular Matrix Biomarkers Illuminate the Architecture of Portal Hypertension in End-Stage Liver Disease-Authors' Reply
Mattias Mandorfer,
Benedikt Simbrunner,
Diana Julie Leeming.
Aliment Pharmacol Ther. 2026 Mar;63(5):743-744. doi: 10.1111/apt.70499. Epub 2025 Dec 21.
2025
Hepatic Recompensation Before Systemic Therapy for Hepatocellular Carcinoma Yields Comparable Survival to Compensated Cirrhosis
Lorenzo Lani,
Bernhard Scheiner,
Matthias Pinter,
Thomas Reiberger.
Liver Int. 2025 Dec;45(12):e70413. doi: 10.1111/liv.70413.
2025
Biomarkers of Extracellular Matrix Remodelling Are Linked to Severity and Outcome of Advanced Chronic Liver Disease
Benedikt Simbrunner,
Ida Falk Villesen,
Georg Semmler,
Lorenz Balcar,
Georg Kramer,
Joana Almeida Calvão,
Benedikt Silvester Hofer,
Mathias Jachs,
Lukas Hartl,
Jurij Maurer,
Bernhard Scheiner,
Kerstin Zinober,
Rodrig Marculescu,
Michael Trauner,
Morten Karsdal,
Thomas Reiberger,
Mattias Mandorfer,
Diana Julie Leeming.
Aliment Pharmacol Ther. 2026 Mar;63(5):648-661. doi: 10.1111/apt.70407. Epub 2025 Oct 12.
2025
Impact of Underlying Portal Hypertension on Severity and Course of Acute-On-Chronic Liver Failure
Vlad Taru,
Georg Kramer,
Benedikt S Hofer,
Nina Dominik,
Lorenz Balcar,
Mathias Schneeweiss-Gleixner,
Bogdan Procopet,
Michael Trauner,
Mattias Mandorfer,
Philipp Schwabl,
Thomas Reiberger,
Benedikt Simbrunner.
Liver Int. 2025 Oct;45(10):e70363. doi: 10.1111/liv.70363.
2025
Loss of Bile Salt Export Pump (Bsep/Abcb11) Ameliorates Toxin-induced Hepatic Fibrosis via Suppression of Hepatocellular Jun Amino-terminal Kinase Signaling and Hepatic Stellate Cell Activation
Claudia D Fuchs,
Emmanuel D Dixon,
Philipp Königshofer,
Thierry Claudel,
Veronika Mlitz,
Hubert Scharnagl,
Tatjana Stojakovic,
Thomas Reiberger,
Michael Trauner.
Cell Mol Gastroenterol Hepatol. 2026;20(1):101630. doi: 10.1016/j.jcmgh.2025.101630. Epub 2025 Sep 12.
2025
Molecular patterns of the NO-sGC-cGMP pathway in progressive and regressive liver fibrosis models
Thomas Sorz-Nechay,
Ksenia Brusilovskaya,
Philipp Königshofer,
Benedikt S Hofer,
Oleksandr Petrenko,
Benedikt Simbrunner,
Vlad Taru,
Katharina Bonitz,
Henriette Horstmeier,
Kerstin Zinober,
Katharina Regnat,
Carolin Lackner,
Michael Trauner,
Peng Sun,
Ines Truebenbach,
Stefan G Kauschke,
Philipp Schwabl,
Thomas Reiberger.
Sci Rep. 2025 Jul 25;15(1):27051. doi: 10.1038/s41598-025-12381-0.
2025
Author's reply: "Aetiology-specific inflammation patterns in patients and rat models of compensated cirrhosis: New perspectives and recommendations"
Benedikt Silvester Hofer,
Thomas Reiberger.
Dig Liver Dis. 2025 Jun;57(6):1350-1351. doi: 10.1016/j.dld.2025.04.022. Epub 2025 May 2.
2025
Author's Reply: "Comment on: Aetiology-specific inflammation patterns in patients and rat models of compensated cirrhosis"
Benedikt Silvester Hofer,
Thomas Reiberger.
Dig Liver Dis. 2025 Jun;57(6):1344-1345. doi: 10.1016/j.dld.2025.03.018. Epub 2025 Apr 2.
2024
Inflammation remains a dynamic component of portal hypertension in regressive alcohol-related cirrhosis
Benedikt Silvester Hofer,
Benedikt Simbrunner,
Philipp Königshofer,
Ksenia Brusilovskaya,
Oleksandr Petrenko,
Vlad Taru,
Thomas Sorz-Nechay,
Kerstin Zinober,
Katharina Regnat,
Georg Semmler,
Carolin Lackner,
Michael Trauner,
Mattias Mandorfer,
Philipp Schwabl,
Thomas Reiberger.
United European Gastroenterol J. 2025 Apr;13(3):317-329. doi: 10.1002/ueg2.12643. Epub 2024 Dec 21.
