Publications
2013
A reversible gene trap collection empowers haploid genetics in human cells.
Bürckstümmer T,
Banning C,
Hainzl P,
Schobesberger R,
Kerzendorfer C,
Pauler FM,
Chen D,
Them N,
Schischlik F,
Rebsamen M,
Smida M,
Fece de la Cruz F,
Lapao A,
Liszt M,
Eizinger B,
Guenzl PM,
Blomen VA,
Konopka T,
Gapp B,
Parapatics K,
Maier B,
Stöckl J,
Fischl W,
Salic S,
Taba Casari MR,
Knapp S,
Bennett KL,
Bock C,
Colinge J,
Kralovics R,
Ammerer G,
Casari G,
Brummelkamp TR,
Superti-Furga G,
Nijman SM.
Nat Methods. 2013 Oct;10(10):965-71.
2013
Cancer. Potential of the synthetic lethality principle.
Nijman SM,
Friend SH.
Potential of the synthetic lethality principle. Science. 2013 Nov 15;342(6160):809-11. doi: 10.1126/science.1244669.
2013
In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen.
Kretschy N,
Teichmann M,
Kopf S,
Atanasov AG,
Saiko P,
Vonach C,
Viola K,
Giessrigl B,
Huttary N,
Raab I,
Krieger S,
Jäger W,
Szekeres T,
Nijman SM,
Mikulits W,
Dirsch VM,
Dolznig H,
Grusch M,
Krupitza G.
Br J Cancer. 2013 Feb 19;108(3):570-8.
2012
Ubiquitin-Specific Protease 4 Inhibits Mono-Ubiquitination of the Master Growth Factor Signaling Kinase PDK1.
Uras IZ,
List T,
Nijman SM.
PloS One 2012;7(2):e31003.
2012
Functional drug-gene interactions in lung cancer.
Smida M,
Nijman SM.
Expert Rev. Mol. Diagn. 2012 Apr;12(3):291-302.
2011
p19(ARF) /p14(ARF) controls oncogenic functions of signal transducer and activator of transcription 3 in hepatocellular carcinoma.
Schneller D,
Machat G,
Sousek A,
Proell V,
van Zijl F,
Zulehner G,
Huber H,
Mair M,
Muellner MK,
Nijman SM,
Eferl R,
Moriggl R,
Mikulits W.
Hepatology. 2011 Jul;54(1):164-72.
2011
Synthetic lethality: general principles, utility and detection using genetic screens in human cells.
Nijman SM.
FEBS Lett. 2011 Jan 3;585(1):1-6.
2011
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.
Muellner MK,
Uras IZ,
Gapp BV,
Kerzendorfer C,
Smida M,
Lechtermann H,
Craig-Mueller N,
Colinge J,
Duernberger G,
Nijman SM.
Nat Chem Biol. 2011 Nov;7(11):787-93.
2011
Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis.
Hoermann G,
Cerny-Reiterer S,
Perne A,
Klauser M,
Hoetzenecker K,
Klein K,
Mullauer L,
Groger M,
Nijman SM,
Klepetko W,
Valent P,
Mayerhofer M.
Am J Pathol. 2011 May;178(5):2344-56.
2010
Syntehtic lethality: General principles, utility and detection using genetic screens in human cells.
Nijman SM.
FEBS Lett. 2010 Nov 19.
