Publications
2019
Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions.
Jia R,
Kralovics R.
Int J Hematol. 2019 Nov 18. doi: 10.1007/s12185-019-02778-9.
2019
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Sdelci S,
Rendeiro AF,
Rathert P,
You W,
Lin JG,
Ringler A,
Hofstätter G,Moll HP,
Gürtl B,
Farlik M,
Schick S,
Klepsch F,
Oldach M,
Buphamalai P,Schischlik F,
Májek P,
Parapatics K,
Schmidl C,
Schuster M,
Penz T,
Buckley DL,Hudecz O,
Imre R,
Wang SY,
Maric HM,
Kralovics R,
Bennett KL,
Müller AC,
MechtlerK,
Menche J,
Bradner JE,
Winter GE,
Klavins K,
Casanova E,
Bock C,
Zuber J,Kubicek S.
Nat Genet. 2019 Jun;51(6):990-998. doi:10.1038/s41588-019-0413-z. Epub 2019 May 27.
2019
Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.
Pecquet C,
Chachoua I,
Roy A,
Balligand T,
Vertenoeil G,
Leroy E,
Albu RI,Defour JP,
Nivarthi H,
Hug E,
Xu E,
Ould-Amer Y,
Mouton C,
Colau D,
Vertommen D,
Shwe MM,
Marty C,
Plo I,
Vainchenker W,
Kralovics R,
Constantinescu SN.
Blood. 2019 Jun 20;133(25):2669-2681. doi:10.1182/blood-2018-09-874578. Epub 2019 Mar 22.
2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms.
Schischlik F,
Jäger R,
Rosebrock F,
Hug E,
Schuster M,
Holly R,
Fuchs E,Milosevic Feenstra JD,
Bogner E,
Gisslinger B,
Schalling M,
Rumi E,
Pietra D,Fischer G,
Faé I,
Vulliard L,
Menche J,
Haferlach T,
Meggendorfer M,
Stengel A,Bock C,
Cazzola M,
Gisslinger H,
Kralovics R.
Blood. 2019 Jul 11;134(2):199-210. doi: 10.1182/blood.2019000519. Epub2019 May 7.
2019
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.
Maurer B,
Nivarthi H,
Wingelhofer B,
Pham HTT,
Schlederer M,
Suske T,Grausenburger R,
Schiefer AI,
Prchal-Murphy M,
Chen D,
Winkler S,
Merkel O,Kornauth C,
Hofbauer M,
Hochgatterer B,
Hoermann G,
Hoelbl-Kovacic A,
ProchazkovaJ,
Lobello C,
Cumaraswamy AA,
Latzka J,
Kitzwögerer M,
Chott A,
Janikova A,Pospíšilova Š,
Loizou JI,
Kubicek S,
Valent P,
Kolbe T,
Grebien F,
Kenner L,Gunning PT,
Kralovics R,
Herling M,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
Haematologica. 2019 May 23. pii: haematol.2019.216986. doi:10.3324/haematol.2019.216986. [Epub ahead of print]
2019
Interplay of transcription factors STAT3, STAT1 and AP-1 mediates activity of the matrix metallo-proteinase-1 promoter in colorectal carcinoma cells.
Muller A,
Gasch J,
Albring KF,
Aberger F,
Nivarthi H,
Khemeri M,
Moriggl R,
Friedrich KH.
Neoplasma. 2019 May 23;66(3):357-366. doi: 10.4149/neo_2018_180731N560.
2019
CDK6 coordinates JAK2V617F mutant MPN via NF-κB and apoptotic networks.
Uras IZ,
Maurer B,
Nivarthi H,
Jodl P,
Kollmann K,
Prchal-Murphy M,
Milosevic Feenstra JD,
Zojer M,
Lagger S,
Grausenburger R,
Grabner B,
Holly R,
Kavirayani A, Bock C,
Gisslinger H,
Valent P,
Kralovics R,
Sexl V.
Blood. 2019;133(15):1677–1690. doi:10.1182/blood-2018-08-872648
2019
Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer.
Unterleuthner D,
Neuhold P,
Schwarz K,
Janker L,
Neuditschko B,
Nivarthi H,
Crncec I,
Kramer N,
Unger C,
Hengstschläger M,
Eferl R,
Moriggl R,
Sommergruber W,
Gerner C,
Dolznig H.
Angiogenesis. 2019 Oct 30. doi: 10.1007/s10456-019-09688-8.
2019
International external quality assurance of JAK2V617F quantification.
Asp J,
Skov V,
Bellosillo B,
Kristensen T,
Lippert E,
Dicker F,
Schwarz J,Wojtaszewska M,
Palmqvist L,
Akiki S,
Aggerholm A,
Tolstrup Andersen M,
GirodonF,
Kjær L,
Oppliger Leibundgut E,
Pancrazzi A,
Vorland M,
Andrikovics H,Kralovics R,
Cassinat B,
Coucelo M,
Eftimov A,
Haslam K,
Kusec R,
Link-LenczowskaD,
Lodé L,
Matiakowska K,
Naguib D,
Navaglia F,
Novotny GW,
Percy MJ,
SudarikovA,
Hermouet S,
Pallisgaard N.
Ann Hematol. 2019 May;98(5):1111-1118. doi:10.1007/s00277-018-3570-8. Epub 2018 Dec 8.
2018
Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo.
Verger E,
Soret-Dulphy J,
Maslah N,
Roy L,
Rey J,
Ghrieb Z,
Kralovics R,
Gisslinger H,
Grohmann-Izay B,
Klade C,
Chomienne C,
Giraudier S,
Cassinat B,
Kiladjian JJ.
Blood Cancer J. 2018 Oct 4;8(10):94. doi: 10.1038/s41408-018-0133-0.
