Publications
2021
Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor.
Jia R,
Balligand T,
Atamanyuk V,
Nivarthi H,
Xu E,
Kutzner L,
Weinzierl J,
Nedelec A,
Kubicek S,
Lesyk R,
Zagrijtschuk O,
Constantinescu SN,
Kralovics R.
Blood. 2021 Apr 8;137(14):1920-1931. doi: 10.1182/blood.2020006264.
2020
Myelomonocytic Skewing In Vitro Discriminates Subgroups of Patients with Myelofibrosis with A Different Phenotype, A Different Mutational Profile and Different Prognosis.
Geissler K,
Gisslinger B,
Jäger E,
Jäger R,
Schiefer AI,
Bogner E,
Fuchs E,
Schischlik F,
Alpar D,
Simonitsch-Klupp I,
Kralovics R,
Gisslinger H.
Cancers (Basel). 2020 Aug 14;12(8):2291. doi: 10.3390/cancers12082291.
2020
Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age Groups.
Gisslinger H,
Klade C,
Georgiev P,
Krochmalczyk D,
Gercheva-Kyuchukova L,
Egyed M,
Rossiev V,
Dulicek P,
Illes A,
Pylypenko H,
Sivcheva L,
Mayer J,
Yablokova V,
Krejcy K,
Hasselbalch HC,
Kralovics R,
Kiladjian JJ.
Hemasphere. 2020 Oct 20;4(6):e485. doi: 10.1097/HS9.0000000000000485.
2020
5-Arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones with selective inhibitory activity against some leukemia cell lines.
Subtelna I,
Kryshchyshyn-Dylevych A,
Jia R,
Lelyukh M,
Ringler A,
Kubicek S,
Zagrijtschuk O,
Kralovics R,
Lesyk R.
Arch Pharm (Weinheim). 2021 Apr;354(4):e2000342. doi: 10.1002/ardp.202000342. Epub 2020 Nov 25.
2020
Multimodality imaging beyond CLEM: Showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions.
Keuenhof K,
Heimel P,
Zopf LM,
Raigel M,
Turyanskaya A,
Kavirayani A,
Reier S,
Glösmann M,
Schöfer C,
Kralovics R,
Streli C,
Weninger WJ,
Geyer SH,
Slezak P,
Macfelda K,
Jäger R,
Wanek T,
Walter A.
Methods Cell Biol. 2021;162:389-415. doi: 10.1016/bs.mcb.2020.10.002. Epub 2020 Dec 2.
2020
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.
Maurer B,
Nivarthi H,
Wingelhofer B,
Pham HTT,
Schlederer M,
Suske T,
Grausenburger R,
Schiefer AI,
Prchal-Murphy M,
Chen D,
Winkler S,
Merkel O,
Kornauth C,
Hofbauer M,
Hochgatterer B,
Hoermann G,
Hoelbl-Kovacic A,
Prochazkova J,
Lobello C,
Cumaraswamy AA,
Latzka J,
Kitzwögerer M,
Chott A,
Janikova A,
Pospíšilova Š,
Loizou JI,
Kubicek S,
Valent P,
Kolbe T,
Grebien F,
Kenner L,
Gunning PT,
Kralovics R,
Herling M,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986.
2020
Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non- inferiority, phase 3 trial and its extension study.
Gisslinger H,
Klade C,
Georgiev P,
Krochmalczyk D,
Gercheva-Kyuchukova L,
Egyed M,
Rossiev V,
Dulicek P,
Illes A,
Pylypenko H,
Sivcheva L,
Mayer J,
Yablokova V,
Krejcy K,
Grohmann-Izay B,
Hasselbalch HC,
Kralovics R,
Kiladjian JJ; PROUD-PV Study Group.
Lancet Haematol. 2020 Mar;7(3):e196-e208. doi: 10.1016/S2352-3026(19)30236-4. Epub 2020 Jan 31. Erratum in: Lancet Haematol. 2020 Feb 25.
2020
Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions.
Jia R,
Kralovics R.
Int J Hematol. 2020 Feb;111(2):182-191. doi: 10.1007/s12185-019-02778-9. Epub 2019 Nov 18.
2020
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.
Balligand T,
Achouri Y,
Pecquet C,
Gaudray G,
Colau D,
Hug E,
Rahmani Y,
Stroobant V,
Plo I,
Vainchenker W,
Kralovics R,
Van den Eynde BJ,
Defour JP,
Constantinescu SN.
Leukemia. 2020 Feb;34(2):510-521. doi: 10.1038/s41375-019-0538-1. Epub 2019 Aug 30.
2019
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.
Balligand T,
Achouri Y,
Pecquet C,
Gaudray G,
Colau D,
Hug E,
Rahmani Y,
Stroobant V,
Plo I,
Vainchenker W,
Kralovics R,
Van den Eynde BJ,
Defour JP,
Constantinescu SN.
Leukemia. 2019 Aug 30. doi: 10.1038/s41375-019-0538-1.
