Publications
2021
Multimodality imaging beyond CLEM: Showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions.
Keuenhof K,
Heimel P,
Zopf LM,
Raigel M,
Turyanskaya A,
Kavirayani A,
Reier S,
Glösmann M,
Schöfer C,
Kralovics R,
Streli C,
Weninger WJ,
Geyer SH,
Slezak P,
Macfelda K,
Jäger R,
Wanek T,
Walter A.
Methods Cell Biol. 2021;162:389-415. doi: 10.1016/bs.mcb.2020.10.002. Epub 2020 Dec 2.
2021
Germline genetic factors influence the outcome of interferon-α therapy in polycythemia vera.
Jäger R,
Gisslinger H,
Fuchs E,
Bogner E,
Milosevic Feenstra JD,
Weinzierl J,
Schischlik F,
Gisslinger B,
Schalling M,
Zörer M,
Krejcy K,
Klade C,
Kralovics R.
Blood. 2021 Jan 21;137(3):387-391. doi: 10.1182/blood.2020005792.
2021
Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.
Valent P,
Orfao A,
Kubicek S,
Staber P,
Haferlach T,
Deininger M,
Kollmann K,
Lion T,
Virgolini I,
Winter G,
Hantschel O,
Kenner L,
Zuber J,
Grebien F,
Moriggl R,
Hoermann G,
Hermine O,
Andreeff M,
Bock C,
Mughal T,
Constantinescu SN,
Kralovics R,
Sexl V,
Skoda R,
Superti-Furga G,
Jäger U.
Hemasphere. 2021 Feb 17;5(3):e536. doi: 10.1097/HS9.0000000000000536. eCollection 2021 Mar.
2021
Hematopoietic expression of a chimeric murine-human CALR oncoprotein allows the assessment of anti-CALR antibody immunotherapies in vivo.
Achyutuni S,
Nivarthi H,
Majoros A,
Hug E,
Schueller C,
Jia R,
Varga C,
Schuster M,
Senekowitsch M,
Tsiantoulas D,
Kavirayani A,
Binder CJ,
Bock C,
Zagrijtschuk O,
Kralovics R.
Am J Hematol. 2021 Mar 24. doi: 10.1002/ajh.26171. Online ahead of print.
2021
Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor.
Jia R,
Balligand T,
Atamanyuk V,
Nivarthi H,
Xu E,
Kutzner L,
Weinzierl J,
Nedelec A,
Kubicek S,
Lesyk R,
Zagrijtschuk O,
Constantinescu SN,
Kralovics R.
Blood. 2021 Apr 8;137(14):1920-1931. doi: 10.1182/blood.2020006264.
2020
High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.
Maurer B,
Nivarthi H,
Wingelhofer B,
Pham HTT,
Schlederer M,
Suske T,
Grausenburger R,
Schiefer AI,
Prchal-Murphy M,
Chen D,
Winkler S,
Merkel O,
Kornauth C,
Hofbauer M,
Hochgatterer B,
Hoermann G,
Hoelbl-Kovacic A,
Prochazkova J,
Lobello C,
Cumaraswamy AA,
Latzka J,
Kitzwögerer M,
Chott A,
Janikova A,
Pospíšilova Š,
Loizou JI,
Kubicek S,
Valent P,
Kolbe T,
Grebien F,
Kenner L,
Gunning PT,
Kralovics R,
Herling M,
Müller M,
Rülicke T,
Sexl V,
Moriggl R.
Haematologica. 2020 Jan 31;105(2):435-447. doi: 10.3324/haematol.2019.216986.
2020
Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non- inferiority, phase 3 trial and its extension study.
Gisslinger H,
Klade C,
Georgiev P,
Krochmalczyk D,
Gercheva-Kyuchukova L,
Egyed M,
Rossiev V,
Dulicek P,
Illes A,
Pylypenko H,
Sivcheva L,
Mayer J,
Yablokova V,
Krejcy K,
Grohmann-Izay B,
Hasselbalch HC,
Kralovics R,
Kiladjian JJ; PROUD-PV Study Group.
Lancet Haematol. 2020 Mar;7(3):e196-e208. doi: 10.1016/S2352-3026(19)30236-4. Epub 2020 Jan 31. Erratum in: Lancet Haematol. 2020 Feb 25.
2020
Progress in elucidation of molecular pathophysiology of myeloproliferative neoplasms and its application to therapeutic decisions.
Jia R,
Kralovics R.
Int J Hematol. 2020 Feb;111(2):182-191. doi: 10.1007/s12185-019-02778-9. Epub 2019 Nov 18.
2020
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.
Balligand T,
Achouri Y,
Pecquet C,
Gaudray G,
Colau D,
Hug E,
Rahmani Y,
Stroobant V,
Plo I,
Vainchenker W,
Kralovics R,
Van den Eynde BJ,
Defour JP,
Constantinescu SN.
Leukemia. 2020 Feb;34(2):510-521. doi: 10.1038/s41375-019-0538-1. Epub 2019 Aug 30.
2019
Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.
Balligand T,
Achouri Y,
Pecquet C,
Gaudray G,
Colau D,
Hug E,
Rahmani Y,
Stroobant V,
Plo I,
Vainchenker W,
Kralovics R,
Van den Eynde BJ,
Defour JP,
Constantinescu SN.
Leukemia. 2019 Aug 30. doi: 10.1038/s41375-019-0538-1.
