2025
Defining the vascular niche of human adipose tissue across metabolic states
Ibrahim AlZaim,
Mohamed N Hassan,
Maja Schröter,
Luca Mannino,
Katarina Dragicevic,
Marie Balle Sjogaard,
Joseph Festa,
Lolita Dokshokova,
Sophie Weinbrenner,
Blanca Tardajos Ayllon,
Bettina Hansen,
Rikke Kongsgaard Rasmussen,
Julie N Christensen,
Olivia Wagman,
Ruby Schipper,
Min Cai,
Wouter Dheedene,
Anja Bille Bohn,
Jean Farup,
Lin Lin,
Samuele Soraggi,
Anna Dalsgaard Thorsen,
Amanda Bæk,
Henrik Holm Thomsen,
Maximilian von Heesen,
Lena-Christin Conradi,
Paul Evans,
Carolina E Hagberg,
None Joerg Heeren,
Margo Emont,
Evan D Rosen,
Aernout Luttun,
Anders Etzerodt,
Lucas Massier,
Mikael Rydén,
Niklas Mejhert,
Matthias Blüher,
Konstantin Khodosevich,
Robert A Fenton,
Bilal N Sheikh,
Niels Jessen,
Laura P M H de Rooij,
Joanna Kalucka.
bioRxiv [Preprint]. 2025 Sep 22:2024.09.22.610444. doi: 10.1101/2024.09.22.610444.
2025
Systematic discovery of CRISPR-boosted CAR T cell immunotherapies
Paul Datlinger,
Eugenia V Pankevich,
Cosmas D Arnold,
Nicole Pranckevicius,
Jenny Lin,
Daria Romanovskaia,
Moritz Schaefer,
Francesco Piras,
Anne-Christine Orts,
Amelie Nemc,
Paulina N Biesaga,
Michelle Chan,
Teresa Neuwirth,
Artem V Artemov,
Wentao Li,
Sabrina Ladstätter,
Thomas Krausgruber,
Christoph Bock.
Nature. 2025 Oct;646(8086):963-972. doi: 10.1038/s41586-025-09507-9. Epub 2025 Sep 24.
2025
Impact of Underlying Portal Hypertension on Severity and Course of Acute-On-Chronic Liver Failure
Vlad Taru,
Georg Kramer,
Benedikt S Hofer,
Nina Dominik,
Lorenz Balcar,
Mathias Schneeweiss-Gleixner,
Bogdan Procopet,
Michael Trauner,
Mattias Mandorfer,
Philipp Schwabl,
Thomas Reiberger,
Benedikt Simbrunner.
Liver Int. 2025 Oct;45(10):e70363. doi: 10.1111/liv.70363.
2025
Loss of Bile Salt Export Pump (Bsep/Abcb11) Ameliorates Toxin-induced Hepatic Fibrosis via Suppression of Hepatocellular Jun Amino-terminal Kinase Signaling and Hepatic Stellate Cell Activation
Claudia D Fuchs,
Emmanuel D Dixon,
Philipp Königshofer,
Thierry Claudel,
Veronika Mlitz,
Hubert Scharnagl,
Tatjana Stojakovic,
Thomas Reiberger,
Michael Trauner.
Cell Mol Gastroenterol Hepatol. 2026;20(1):101630. doi: 10.1016/j.jcmgh.2025.101630. Epub 2025 Sep 12.
2025
The Role of Enoxaparin in Influenza Virus Infections and Its Therapeutic Implications
Marta Bermejo-Jambrina,
Viktoria Zaderer,
Julia Eder,
Gabriel Diem,
Killian E Vlaming,
Wilfried Posch,
Teunis B H Geijtenbeek,
Doris Wilflingseder.
J Infect Dis. 2025 Sep 10:jiaf470. doi: 10.1093/infdis/jiaf470. Online ahead of print.
2025
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation
Loïc Dupré,
Irinka Castanon,
Kaan Boztug.
Nat Rev Immunol. 2026 Feb;26(2):89-111. doi: 10.1038/s41577-025-01214-w. Epub 2025 Sep 10.
2025
A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers
Antonio José Cabrera-Serrano,
Lucía Ruiz-Durán,
Juan Francisco Gutiérrez-Bautista,
María Carretero-Fernández,
Rob Ter Horst,
Yang Li,
Fernando Jesús Reyes-Zurita,
Francisco José García-Verdejo,
Mihai G Netea,
Pedro Sánchez-Rovira,
Miguel Ángel López-Nevot,
Antonio Sampedro,
Juan Sainz.
Front Immunol. 2025 Aug 18;16:1639825. doi: 10.3389/fimmu.2025.1639825. eCollection 2025.
2025
Artificial Intelligence and Network Medicine: Path to Precision Medicine
Lucia Altucci,
Lina Badimon,
Jean-Luc Balligand,
Jan Baumbach,
Alberico L Catapano,
Feixong Cheng,
Dawn DeMeo,
Rajat Gupta,
Marcus Hacker,
Yang-Yu Liu,
Joseph Loscalzo,
Sabrina Maniscalco,
Jörg Menche,
Giulia Menichetti,
Paolo Parini,
Harald H H W Schmidt,
Marinka Zitnik.
NEJM AI. 2025 Sep;2(9):10.1056/aira2401229. doi: 10.1056/aira2401229. Epub 2025 Aug 28.
2025
Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia
Antonio José Cabrera-Serrano,
José Manuel Sánchez-Maldonado,
Juan José Rodríguez-Sevilla,
Fernando Jesús Reyes-Zurita,
Rosa Collado,
Anna Puiggros,
Elena Cornejo-Calvo,
Paloma García-Martín,
Rob Ter Horst,
Yolanda Benavente,
Andrés Jerez,
Stefano Landi,
Blanca Espinet,
Rossana Maffei,
Miguel Ángel López-Nevot,
Silvia Ramos-Campoy,
Carmen González-Olmedo,
Tzu-Hua Chen-Liang,
Víctor Moreno,
Fatin Jannus,
Rafael Marcos-Gragera,
María Carretero-Fernández,
Belém Sampaio-Marques,
Irene Gámez,
María García-Álvarez,
Nicola J Camp,
Trinidad Dierssen-Sotos,
Joanna Kamaso,
Eva María Pérez,
Aaron D Norman,
Mario Luppi,
Yang Li,
Miguel Alcoceba,
Daniele Campa,
Silvia de San José,
Roberto Marasca,
Paula Ludovico,
Alyssa Clay-Gilmour,
Federico Canzian,
Marian Ibañez,
Mihai G Netea,
James McKay,
Delphine Casabonne,
Sonja I Berndt,
Susan L Slager,
Juan Sainz.
Blood Adv. 2025 Dec 9;9(23):6076-6089. doi: 10.1182/bloodadvances.2025017345.
2025
Chemokine Receptor Profiles as Predictors of Survival and Early Progression in Follicular Lymphoma
Antonella Zupo,
Katrin Pansy,
Lukas Gaksch,
Julia Waldhart,
Andrea Brunner,
Johanna Strobl,
Marta Szmyra-Polomka,
Sandra Haingartner,
Peter V Tomazic,
Hildegard T Greinix,
Barbara Uhl,
Julia Feichtinger,
Georg Stary,
Johannes Haybaeck,
Fotini Rosi Vagena,
Martin Zacharias,
Christine Beham-Schmid,
Peter Neumeister,
Katharina Theresa Prochazka,
Alexander J A Deutsch.
EJHaem. 2025 Aug 28;6(5):e70131. doi: 10.1002/jha2.70131. eCollection 2025 Oct.
