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2021

Characterization of CD8 T Cell-Mediated Mutations in the Immunodominant Epitope GP33-41 of Lymphocytic Choriomeningitis Virus

Smyth M, Khamina K, Popa A, Gudipati V, Agerer B, Lercher A, Kosack L, Endler L, Baazim H, Viczenczova C, Huppa JB, Bergthaler A.
Front Immunol. 2021 Jun 14;12:638485. doi: 10.3389/fimmu.2021.638485. eCollection 2021.
2021

Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution.

Busslinger G, Weusten BLA, Bogte A, Begthel H, Brosens LAA, Clevers H.
Cell Rep. 2021 Mar 9;34(10):108819.
2021

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions

Peter Valent, Alberto Orfao, Stefan Kubicek, Philipp Staber, Torsten Haferlach, Michael Deininger, Karoline Kollmann, Thomas Lion, Irene Virgolini, Georg Winter, Oliver Hantschel, Lukas Kenner, Johannes Zuber, Florian Grebien, Richard Moriggl, Gregor Hoermann, Olivier Hermine, Michael Andreeff, Christoph Bock, Tariq Mughal, Stefan N Constantinescu, Robert Kralovics, Veronika Sexl, Radek Skoda, Giulio Superti-Furga, Ulrich Jäger.
Hemasphere. 2021 Feb 17;5(3):e536. doi: 10.1097/HS9.0000000000000536. eCollection 2021 Mar.
2021

Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression

Stefan Terlecki-Zaniewicz, Theresa Humer, Thomas Eder, Johannes Schmoellerl, Elizabeth Heyes, Gabriele Manhart, Natalie Kuchynka, Katja Parapatics, Fabio G Liberante, André C Müller, Eleni M Tomazou, Florian Grebien.
Nat Struct Mol Biol. 2021 Feb;28(2):190-201. doi: 10.1038/s41594-020-00550-w. Epub 2021 Jan 21.
2020

Clinical Course of Porto-Sinusoidal Vascular Disease Is Distinct From Idiopathic Noncirrhotic Portal Hypertension.

Kretzmer H, Biran A, Purroy N, Lemvigh C, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes S, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps 9: Wöran K, Semmler G, Jachs M, Simbrunner B, Maria Bauer DJ, Binter T, Pomej K, Stättermayer AF, Schwabl P, Bucsics T, Paternostro R, Lampichler K, Pinter M, Trauner M, Mandorfer M, Stift J, Reiberger T, Scheiner B.
Clin Gastroenterol Hepatol. 2020 Dec 3:S1542-3565(20)31629-3. doi: 10.1016/j.cgh.2020.11.039. Epub ahead of print.
2020

Targeted protein degradation: current and future challenges.

Hanzl A, Winter GE.
Curr Opin Chem Biol. 2020 Jun;56:35-41. doi: 10.1016/j.cbpa.2019.11.012. Epub 2020 Jan 2. PMID: 31901786.
2020

MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment.

Haschka MD, Karbon G, Soratroi C, O'Neill KL, Luo X, Villunger A.
Cell Death Differ. 2020 Aug;27(8):2297-2312. doi: 10.1038/s41418-020-0503-6. Epub 2020 Feb 3.
2020

Patient-derived model systems and the development of next-generation anticancer therapeutics.

Krall N, Superti-Furga G, Vladimer GI.
Curr Opin Chem Biol. 2020 Jun;56:72-78. doi: 10.1016/j.cbpa.2020.01.002. Epub 2020 Feb 18.
2020

Drp1 modulates mitochondrial stress responses to mitotic arrest.

Peña-Blanco A, Haschka MD, Jenner A, Zuleger T, Proikas-Cezanne T, Villunger A, García-Sáez AJ.
Cell Death Differ. 2020 Sep;27(9):2620-2634. doi: 10.1038/s41418-020-0527-y. Epub 2020 Mar 19.
2020

Anti-Apoptotic Molecule BCL2 Is a Therapeutic Target in Steroid-Refractory Graft-Versus-Host Disease.

Strobl J, Pandey RV, Krausgruber T, Kleissl L, Reininger B, Herac M, Bayer N, Krall C, Wohlfarth P, Mitterbauer M, Kalhs P, Rabitsch W, Bock C, Hopfinger G, Stary G.
J Invest Dermatol. 2020 Nov;140(11):2188-2198. doi: 10.1016/j.jid.2020.02.029. Epub 2020 Apr 2.