2021
Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells.
Saluzzo S,
Pandey RV,
Gail LM,
Dingelmaier-Hovorka R,
Kleissl L,
Shaw L,
Reininger B,
Atzmüller D,
Strobl J,
Touzeau-Römer V,
Beer A,
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Farlik M,
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Immunity. 2021 Nov 16;S1074-7613(21)00459-3. doi: 10.1016/j.immuni.2021.10.021. Online ahead of print.
2021
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
Casteels T,
Zhang Y,
Frogne T,
Sturtzel C,
Lardeau CH,
Sen I,
Liu X,
Hong S,
Pauler FM,
Penz T,
Brandstetter M,
Barbieux C,
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Heuser T,
Bock C,
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Mol Metab. 2021 Dec;54:101329. doi: 10.1016/j.molmet.2021.101329. Epub 2021 Aug 25.
2021
High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells.
Jia R,
Kutzner L,
Koren A,
Runggatscher K,
Májek P,
Müller AC,
Schuster M,
Bock C,
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Kralovics R.
Blood Cancer J. 2021 Jul 31;11(7):137. doi: 10.1038/s41408-021-00531-2.
2021
Profiling biological perturbations with high-content imaging in single cells and heterogeneous populations.
Vulliard L,
Hancock J,
Kamnev A,
Fell CW,
Ferreira da Silva J,
Loizou JI,
Nagy V,
Dupré L,
Menche J.
jl: Profiling biological perturbations with high-content imaging in single cells and heterogeneous populations. Bioinformatics. 2021 Dec 22;38(6):1692-9. doi: 10.1093/bioinformatics/btab853. Online ahead of print.
2021
Discovering common pathogenetic processes between COVID-19 and diabetes mellitus by differential gene expression pattern analysis.
Rahman MR,
Islam T,
Shahjaman M,
Islam MR,
Lombardo SD,
Bramanti P,
Ciurleo R,
Bramanti A,
Tchorbanov A,
Fisicaro F,
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Nicoletti F,
Pennisi M.
Brief Bioinform. 2021 Nov 5;22(6):bbab262. doi: 10.1093/bib/bbab262.
2021
Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators.
Pennemann FL,
Mussabekova A,
Urban C,
Stukalov A,
Andersen LL,
Grass V,
Lavacca TM,
Holze C,
Oubraham L,
Benamrouche Y,
Girardi E,
Boulos RE,
Hartmann R,
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Imler JL,
Meignin C,
Pichlmair A.
Nat Commun. 2021 Dec 1;12(1):7009. doi: 10.1038/s41467-021-27192-w.
2021
The Immunological Factors Predisposing to Severe Covid-19 Are Already Present in Healthy Elderly and Men.
Kilic G,
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Jaeger M,
Ter Horst R,
Koeken VACM,
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Front Immunol. 2021 Aug 9;12:720090. doi: 10.3389/fimmu.2021.720090. eCollection 2021.
2021
Breast Cancer Transcriptional Regulatory Network Reprogramming by using the CRISPR/Cas9 System: An Oncogenetics Perspective.
Singh DD,
Verma R,
Tripathi SK,
Sahu R,
Trivedi P,
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Curr Top Med Chem. 2021;21(31):2800-2813. doi: 10.2174/1568026621666210902120754.
2021
Human resident memory T cells exit the skin and mediate systemic Th2-driven inflammation.
Strobl J,
Gail LM,
Kleissl L,
Pandey RV,
Smejkal V,
Huber J,
Puxkandl V,
Unterluggauer L,
Dingelmaier-Hovorka R,
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J Exp Med. 2021 Nov 1;218(11):e20210417. doi: 10.1084/jem.20210417. Epub 2021 Oct 13.
2021
24-Norursodeoxycholic acid reshapes immunometabolism in CD8(+) T cells and alleviates hepatic inflammation.
Zhu C,
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Müller AC,
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Claudel T,
Halilbasic E,
Baazim H,
Lercher A,
Viczenczova C,
Hainberger D,
Preglej T,
Sandner L,
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Gülich AF,
Khan M,
Hamminger P,
Remetic J,
Ohradanova-Repic A,
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Donner C,
Fuchs CD,
Stojakovic T,
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J Hepatol. 2021 Nov;75(5):1164-1176. doi: 10.1016/j.jhep.2021.06.036. Epub 2021 Jul 7.
