2025
Single-cell and chromatin accessibility profiling reveals regulatory programs of pathogenic Th2 cells in allergic asthma
Matarr Khan,
Marlis Alteneder,
Wolfgang Reiter,
Thomas Krausgruber,
Lina Dobnikar,
Moritz Madern,
Monika Waldherr,
Christoph Bock,
Markus Hartl,
Wilfried Ellmeier,
Johan Henriksson,
Nicole Boucheron.
Nat Commun. 2025 Mar 15;16(1):2565. doi: 10.1038/s41467-025-57590-3.
2025
Fluorescent PyrAte-(S)-citalopram conjugates enable imaging of the serotonin transporter in living tissue
Oliver J V Belleza,
Iakovos Saridakis,
Nadja K Singer,
Xavier Westergaard,
Sergio Armentia Matheu,
Miran Lemmerer,
Margaux Riomet,
Pedro A Sánchez-Murcia,
Nina Kastner,
Stefanie Rukavina,
Yi Xiao,
Kathrin Jäntsch,
Marco Niello,
Klaus Schicker,
David Sulzer,
Leticia González,
Nuno Maulide,
Harald H Sitte.
Chem Sci. 2025 Mar 3;16(14):6003-6013. doi: 10.1039/d4sc06949h. eCollection 2025 Apr 2.
2025
Evaluation of Patients with Combined Immunodeficiency: A Single Center Experience
Hatice Firatoglu,
Caner Aytekin,
Figen Dogu,
Sevgi Kostel Bal,
Sule Haskologlu,
Kaan Boztug,
Aydan Ikinciogullari.
Iran J Immunol. 2025 Mar 30;22(1):89-99. doi: 10.22034/iji.2025.103499.2844.
2025
Simultaneous immunomodulation and epithelial-to-mesenchymal transition drives lung adenocarcinoma progression
Junbum Kim,
Hiranmayi Ravichandran,
Liron Yoffe,
Bhavneet Bhinder,
Kyle Finos,
Arshdeep Singh,
Bradley B Pua,
Stewart Bates,
Bevan Emma Huang,
Andre F Rendeiro,
Vivek Mittal,
Nasser K Altorki,
Timothy E McGraw,
Olivier Elemento.
bioRxiv [Preprint]. 2025 Feb 22:2025.02.19.637138. doi: 10.1101/2025.02.19.637138.
2025
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation
Ci Zhu,
Nicole Boucheron,
Osamah Al-Rubaye,
Brian K Chung,
Liv Wenche Thorbjørnsen,
Thomas Köcher,
Michael Schuster,
Thierry Claudel,
Emina Halilbasic,
Victoria Kunczer,
Fanziska Muscate,
Lois L Cavanagh,
Darina Waltenberger,
Alexander Lercher,
Anna Ohradanova-Repic,
Philipp Schatzlmaier,
Tatjana Stojakovic,
Hubert Scharnagl,
Andreas Bergthaler,
Hannes Stockinger,
Samuel Huber,
Christoph Bock,
Lukas Kenner,
Tom H Karlsen,
Wilfried Ellmeier,
Michael Trauner.
Gut. 2025 Jun 6;74(7):1079-1093. doi: 10.1136/gutjnl-2024-333297.
2025
Cell-type-specific requirement for TYK2 in murine immune cells under steady state and challenged conditions
Anzhelika Karjalainen,
Agnieszka Witalisz-Siepracka,
Michaela Prchal-Murphy,
David Martin,
Felix Sternberg,
Milica Krunic,
Marlies Dolezal,
Nikolaus Fortelny,
Matthias Farlik,
Sabine Macho-Maschler,
Caroline Lassnig,
Katrin Meissl,
Lena Amenitsch,
Therese Lederer,
Elena Pohl,
Dagmar Gotthardt,
Christoph Bock,
Thomas Decker,
Birgit Strobl,
Mathias Müller.
Cell Mol Life Sci. 2025 Mar 2;82(1):98. doi: 10.1007/s00018-025-05625-9.
2025
The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation
Teresa Neuwirth,
Daniel Malzl,
Katja Knapp,
Panagiota Tsokkou,
Lisa Kleissl,
Anna Gabriel,
Baerbel Reininger,
Christian Freystätter,
Nara Marella,
Ana P Kutschat,
Elisabeth Ponweiser,
Arvand Haschemi,
Davide Seruggia,
Jörg Menche,
Erwin F Wagner,
Georg Stary.
Immunity. 2025 Mar 11;58(3):632-647.e12. doi: 10.1016/j.immuni.2025.02.011. Epub 2025 Feb 28.
2025
Altered spawning seasons of Atlantic salmon broodstock transcriptionally and epigenetically influence cell cycle and lipid-mediated regulations in their offspring
Takaya Saito,
Marit Espe,
Maren Mommens,
Christoph Bock,
Jorge M O Fernandes,
Kaja Helvik Skjærven.
PLoS One. 2025 Feb 24;20(2):e0317770. doi: 10.1371/journal.pone.0317770. eCollection 2025.
2025
Ex vivo T-lymphopoiesis assays assisting corrective treatment choice for genetically undefined T-lymphocytopenia
Zainab M Golwala,
Helena Spiridou Goncalves,
Ranjita Devi Moirangthem,
Grace Evans,
Sabrina Lizot,
Coco de Koning,
Alexandrine Garrigue,
Marta Martin Corredera,
Juan Moises Ocampo-Godinez,
Evey Howley,
Susanne Kricke,
Arnold Awuah,
Irene Obiri-Yeboa,
Rajeev Rai,
Neil Sebire,
Fanette Bernard,
Victoria Bordon Cueto De Braem,
Kaan Boztug,
Theresa Cole,
Andrew R Gennery,
Scott Hackett,
Sophie Hambleton,
Mette Holm,
Maaike A Kusters,
Adam Klocperk,
Antonio Marzollo,
Nufar Marcus,
Zohreh Nademi,
Jana Pachlopnik Schmid,
Herbert Pichler,
Anna Sellmer,
Pere Soler-Palacin,
Maarja Soomann,
Paul Torpiano,
Joris van Montfrans,
Stefan Nierkens,
Stuart Adams,
Matthew Buckland,
Kimberly Gilmour,
Austen Worth,
Adrian J Thrasher,
E Graham Davies,
Isabelle André,
Alexandra Y Kreins.
Clin Immunol. 2025 May;274:110453. doi: 10.1016/j.clim.2025.110453. Epub 2025 Feb 16.
2025
Single-cell CRISPR screening in mouse brain
Eugenia V Pankevich,
Christoph Bock.
Nat Protoc. 2025 Jul;20(7):1731-1732. doi: 10.1038/s41596-024-01128-2.
