2008
Lipoteichoic Acid-induced Lung Inflammation depends on TLR2 and the concerted action of TLR4 and Platelet-activating Factor Receptor.
Knapp S,
von Aulock S,
Leendertse M,
Haslinger I,
Draing C,
Golenbock DT,
van der Poll T.
Journal of Immunology 2008, 180: 3478–3484.
2008
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury.
Imai Y,
Kuba K,
Neely GG,
Yaghubian-Malhami R,
Perkmann T,
van Loo G,
Ermolaeva M,
Veldhuizen R,
Leung YH,
Wang H,
Liu H,
Sun Y,
Pasparakis M,
Kopf M,
Mech C,
Bavari S,
Peiris JS,
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Hultqvist M,
Holmdahl R,
Nicholls J,
Jiang C,
Binder CJ,
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Cell. 2008, Apr 18;133(2):235–49.
2008
Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib.
Hantschel O,
Rix U,
Superti-Furga G.
Leuk Lymphoma, 2008 Apr;49(4):615-9. Review.
2008
The chemokine IL-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in CML.
Hantschel O,
Gstoettenbauer A,
Colinge J,
Kaupe I,
Bilban M,
Burkard TR,
Valent P,
Superti-Furga G.
Molecular Oncology, Vol 2/Issue3/ October 2008, 272–281.
2008
Structural coupling of Fes and Abl SH2-tyrosine kinase domains links substrate recognition and kinase activation.
Filippakopoulos P,
Kofler M,
Hantschel O,
Gish GD,
Grebien F,
Salah E,
Neudecker P,
Kay LE,
Turk BE,
Superti-Furga G,
Pawson T,
Knapp S.
Cell. 2008 Sep 5;134(5): 793–803.
2008
Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCRABL1 fusion protein kinases.
De Keersmaecker K,
Versele M,
Cools J,
Superti-Furga G,
Hantschel O.
Leukemia. 2008, Dec;22(12):2208–16.
2008
Oxidation-specific epitopes are important targets of innate immunity.
Chou MY,
Hartvigsen K,
Hansen LF,
Fogelstrand L,
Shaw PX,
Boullier A,
Binder CJ,
Witztum JL.
J Intern Med. 2008, May;263(5):479–88. Review.
2008
A neutralizing antibody against receptor for advanced glycation end products (RAGE) reduces atherosclerosis in uremic mice.
Bro S,
Flyvbjerg A,
Binder CJ,
Bang CA,
Denner L,
Olgaard K,
Nielsen LB.
Atherosclerosis. 2008, Dec;201(2):274–80.
