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2015

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.

Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G.
Nature. 2015 Jan 7. doi: 10.1038/nature14107.
2015

Targeting a cell state common to triple-negative breast cancers.

Muellner MK, Mair B, Ibrahim Y, Kerzendorfer C, Lechtermann H, Trefzer C, Klepsch F, Müller AC, Leitner E, Macho-Maschler S, Superti-Furga G, Bennett KL, Baselga J, Rix U, Kubicek S, Colinge J, Serra V, Nijman SM.
Mol Syst Biol. 2015 Feb 19;11(1):789. doi: 10.15252/msb.20145664.
2015

Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.

Lorenz S, Deng P, Hantschel O, Superti-Furga G, Kuriyan J.
Biochem J. 2015 Jun 1;468(2):283-91. doi: 10.1042/BJ20141492.
2015

Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.

Kulinski TM, Casari MR, Guenzl PM, Wenzel D, Andergassen D, Hladik A, Datlinger P, Farlik M, Theussl HC, Penninger JM, Knapp S, Bock C, Barlow DP, Hudson QJ.
Dev Biol. 2015 Jun 15;402(2):291-305. doi: 10.1016/j.ydbio.2015.04.010. Epub 2015 Apr 24.
2015

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.

Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC.
Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112. Epub 2015 Feb 23.
2015

KPC1-mediated ubiquitination and proteasomal processing of NF-_B1 p105 to p50 restricts tumor growth.

Kravtsova-Ivantsiv Y, Shomer I, Cohen-Kaplan V, Snijder B, Superti-Furga G, Gonen H, Sommer T, Ziv T, Admon A, Naroditsky I, Jbara M, Brik A, Pikarsky E, Kwon YT, Doweck I, Ciechanover A.
Cell. 2015 Apr 9;161(2):333-47. doi: 10.1016/j.cell.2015.03.001.
2015

A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses.

Köberlin MS, Snijder B, Heinz LX, Baumann CL, Fauster A, Vladimer GI, Gavin AC, Superti-Furga G.
Cell. 2015 Jul 2;162(1):170-83. doi: 10.1016/j.cell.2015.05.051. Epub 2015 Jun 18.
2015

A thesaurus of genetic variation for interrogation of repetitive genomic regions.

Kerzendorfer C, Konopka T, Nijman SM.
Nucleic Acids Res. 2015 May 26;43(10):e68. doi: 10.1093/nar/gkv178. Epub 2015 Mar 27.
2015

A Modular Synthesis of Modified Phosphoanhydrides.

Hofer A, Cremosnik GS, Müller AC, Giambruno R, Trefzer C, Superti-Furga G, Bennett KL, Jessen HJ.
Chemistry. 2015 Jun 1. doi: 10.1002/chem.201500838.
2015

The RNA-binding protein HuR/ELAVL1 regulates IFN-_ mRNA abundance and the type I IFN response.

Herdy B, Karonitsch T, Vladimer GI, Tan CS, Stukalov A, Trefzer C, Bigenzahn JW, Theil T, Holinka J, Kiener HP, Colinge J, Bennett KL, Superti-Furga G.
Eur J Immunol. 2015 May;45(5):1500-11. doi: 10.1002/eji.201444979. Epub 2015 Mar 12.