2015
DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.
Prochazkova J,
Sakaguchi S,
Owusu M,
Mazouzi A,
Wiedner M,
Velimezi G,
Moder M,
Turchinovich G,
Hladik A,
Gurnhofer E,
Hayday A,
Behrens A,
Knapp S,
Kenner L,
Ellmeier W,
Loizou JI.
PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015.
2015
Programmed DNA breaks in lymphoid cells: Repair mechanisms and consequences in human disease.
Prochazkova J,
Loizou JI.
Immunology. 2015 Oct 12. doi: 10.1111/imm.12547.
2015
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
Peter B,
Winter GE,
Blatt K,
Bennett KL,
Stefanzl G,
Rix U,
Eisenwort G,
Hadzijusufovic E,
Gridling M,
Dutreix C,
Hoermann G,
Schwaab J,
Radia D,
Roesel J,
Manley PW,
Reiter A,
Superti-Furga G,
Valent P.
Leukemia. 2015 Sep 9. doi: 10.1038/leu.2015.242.
2015
Functional genomics to uncover drug mechanism of action.
Nijman SM.
Nat Chem Biol. 2015 Dec;11(12):942-8. doi: 10.1038/nchembio.1963. Epub 2015 Nov 17. Review.
2015
Whole exome sequencing identifies novel MPL and JAK2 mutations in triple negative myeloproliferative neoplasms.
Milosevic Feenstra JD,
Nivarthi H,
Gisslinger H,
Leroy E,
Rumi E,
Chachoua I,
Bagienski K,
Kubesova B,
Pietra D,
Gisslinger B,
Milanesi C,
Jäger R,
Chen D,
Berg T,
Schalling M,
Schuster M,
Bock C,
Constantinescu SN,
Cazzola M,
Kralovics R.
Blood. 2015 Sep 30. pii: blood-2015-07-661835.
2015
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis.
Marty C,
Pecquet C,
Nivarthi H,
Elkhoury M,
Chachoua I,
Tulliez M,
Villeval JL,
Raslova H,
Kralovics R,
Constantinescu SN,
Plo I,
Vainchenker W.
Blood. 2015 Nov 25. pii: blood-2015-11-679571.
2015
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation.
Licciardello MP,
Müllner MK,
Dürnberger G,
Kerzendorfer C,
Boidol B,
Trefzer C,
Sdelci S,
Berg T,
Penz T,
Schuster M,
Bock C,
Kralovics R,
Superti-Furga G,
Colinge J,
Nijman SM,
Kubicek S.
Oncogene. 2015 Jul;34(29):3780-90. doi: 10.1038/onc.2014.319. Epub 2014 Sep 29.
2015
Inflammatory bowel disease phenotype in a young girl with prolidase deficiency: A new spectrum of clinical manifestation.
Kuloglu Z,
Kansu A,
Serwas N,
Demir A,
Yaman A,
Ensari A,
Boztug K.
Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency. Genet Couns. 2015;26(2):205-11.
2015
A human haploid gene trap collection to study lncRNAs with unusual RNA biology.
Kornienko AE,
Vlatkovic I,
Neesen J,
Barlow DP,
Pauler FM.
RNA Biol. 2015 Dec 15:0.
2015
Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis.
Kooij G,
Braster R,
Koning JJ,
Laan LC,
van Vliet SJ,
Los T,
Eveleens AM,
van der Pol SM,
Förster-Waldl E,
Boztug K,
Belot A,
Szilagyi K,
van den Berg TK,
van Buul JD,
van Egmond M,
de Vries HE,
Cummings RD,
Dijkstra CD,
van Die I.
Acta Neuropathol Commun. 2015 Jul 25;3:45. doi: 10.1186/s40478-015-0223-1.