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2016

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.

Tortola L, Nitsch R, Bertrand MJ, Kogler M, Redouane Y, Kozieradzki I, Uribesalgo I, Fennell LM, Daugaard M, Klug H, Wirnsberger G, Wimmer R, Perlot T, Sarao R, Rao S, Hanada T, Takahashi N, Kernbauer E, Demiröz D, Superti-Furga G, Decker T, Pichler A, Ikeda F, Kroemer G, Vandenabeele P, Sorensen PH, Penninger JM.
Cell Rep. 2016 May 17;15(7):1481-92. doi: 10.1016/j.celrep.2016.04.032. Epub 2016 May 5.
2016

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis.

Shimizu T, Kubovcakova L, Nienhold R, Zmajkovic J, Meyer SC, Hao-Shen H, Geier F, Dirnhofer S, Guglielmelli P, Vannucchi AM, Feenstra JD, Kralovics R, Orkin SH, Skoda RC.
J Exp Med. 2016 Jul 25;213(8):1479-96. doi: 10.1084/jem.20151136.
2016

LNK mutations in familial myeloproliferative neoplasms.

Rumi E, Harutyunyan AS, Pietra D, Feenstra JD, Cavalloni C, Roncoroni E, Casetti I, Bellini M, Milanesi C, Renna MC, Gotti M, Astori C, Kralovics R, Cazzola M.
Blood. 2016 Jul 7;128(1):144-5. doi: 10.1182/blood-2016-04-711150
2016

Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks.

Rendeiro AF, Schmidl C, Strefford JC, Walewska R, Davis Z, Farlik M, Oscier D, Bock C.
Nat Commun. 2016 Jun 27;7:11938. doi: 10.1038/ncomms11938.
2016

Overcoming MITF-conferred drug resistance through dual AURKA/MAPK targeting in human melanoma cells.

Pathria G, Garg B, Borgdorff V, Garg K, Wagner C, Superti-Furga G, Wagner SN.
Cell Death Dis. 2016 Mar 10;7:e2135. doi: 10.1038/cddis.2015.369.
2016

Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis.

Papac-Milicevic N, Busch CJ, Binder CJ.
Adv Immunol. 2016;131:1-59. doi: 10.1016/bs.ai.2016.02.001. Epub 2016 Apr 5.
2016

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth.

Nivarthi H, Gordziel C, Themanns M, Kramer N, Eberl M, Rabe B, Schlederer M, Rose-John S, Knösel T, Kenner L, Freund P, Aberger F, Han X, Kralovics R, Dolznig H, Jennek S, Friedrich K, Moriggl R.
Oncotarget. 2016 May 12. doi: 10.18632/oncotarget.9315.
2016

Thrombopoietin receptor is required for the oncogenic function of CALR mutants.

Nivarthi H, Chen D, Cleary C, Kubesova B, Jäger R, Bogner E, Marty C, Pecquet C, Vainchenker W, Constantinescu SN, Kralovics R.
Leukemia. 2016 Feb 17. doi: 10.1038/leu.2016.32.
2016

Identifying Kinase Substrates via a Heavy ATP Kinase Assay and Quantitative Mass Spectrometry.

Müller AC, Giambruno R, Weißer J, Májek P, Hofer A, Bigenzahn JW, Superti-Furga G, Jessen HJ, Bennett KL.
Sci Rep. 2016 Jun 27;6:28107. doi: 10.1038/srep28107.
2016

Specification of tissue-resident macrophages during organogenesis.

Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F.
Science. 2016 Aug 4. pii: aaf4238.