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2016

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S.
Nat Immunol. 2016 Oct 31. doi: 10.1038/ni.3590.
2016

Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.

Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, Moran MF, Grynpas MD, Wrana JL, Superti-Furga G, Koleske AJ, Pendergast AM, Rottapel R.
J Clin Invest. 2016 Dec 1;126(12):4482-4496. doi: 10.1172/JCI87802.
2016

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.

Mazouzi A, Stukalov A, Müller AC, Chen D, Wiedner M, Prochazkova J, Chiang SC, Schuster M, Breitwieser FP, Pichlmair A, El-Khamisy SF, Bock C, Kralovics R, Colinge J, Bennett KL, Loizou JI.
Cell Rep. 2016 Apr 14. pii: S2211-1247(16)30366-7. doi: 10.1016/j.celrep.2016.03.077.
2016

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS.
Cell Rep. 2016 Sep 20;16(12):3311-21. doi: 10.1016/j.celrep.2016.08.056.
2016

IgE and mast cells in host defense against parasites and venoms.

Mukai K, Tsai M, Starkl P, Marichal T, Galli SJ.
Semin Immunopathol. 2016 Sep;38(5):581-603. doi: 10.1007/s00281-016-0565-1. Review.
2016

Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.

Peter B, Winter GE, Blatt K, Bennett KL, Stefanzl G, Rix U, Eisenwort G, Hadzijusufovic E, Gridling M, Dutreix C, Hoermann G, Schwaab J, Radia D, Roesel J, Manley PW, Reiter A, Superti-Furga G, Valent P.
Leukemia. 2016 Feb;30(2):464-72. doi: 10.1038/leu.2015.242.
2016

Neutrophils are not required for resolution of acute gouty arthritis in mice.

Reber LL, Gaudenzio N, Starkl P, Galli SJ.
Nat Med. 2016 Dec 6;22(12):1382-1384. doi: 10.1038/nm.4216.
2016

MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.

Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181.
2016

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics.

Salzer E, Cagdas D, Hons M, Mace EM, Garncarz W, Petronczki ÖY, Platzer R, Pfajfer L, Bilic I, Ban SA, Willmann KL, Mukherjee M, Supper V, Hsu HT, Banerjee PP, Sinha P, McClanahan F, Zlabinger GJ, Pickl WF, Gribben JG, Stockinger H, Bennett KL, Huppa JB, Dupré L, Sanal Ö, Jäger U, Sixt M, Tezcan I, Orange JS, Boztug K.
Nat Immunol. 2016 Dec;17(12):1352-1360. doi: 10.1038/ni.3575.
2016

Protein Kinase C _: a Gatekeeper of Immune Homeostasis.

Salzer E, Santos-Valente E, Keller B, Warnatz K, Boztug K.
J Clin Immunol. 2016 Oct;36(7):631-40.