Publications
2026
Methods to study PIDDosome and caspase-2 signalling
Felix Eichin,
Rotraud Hirschberger,
Andreas Villunger,
Valentina C Sladky.
Methods Cell Biol. 2026;210:17-39. doi: 10.1016/bs.mcb.2026.05.012. Epub 2026 Jun 3.
2026
PIDDosome deficiency impairs bone remodeling by increasing osteoclast ploidy and function
M Leone,
D Obwegs,
N Kinz,
A Maccataio,
G Degenhart,
R Liguori,
P Y Petermann,
V C Sladky,
F Eichin,
J S Riley,
I Dorigatti,
K Watschinger,
D Rizzotto,
F Ferrazzi,
U Steffen,
A Villunger.
Cell Death Differ. 2026 Aug 14. doi: 10.1038/s41418-026-01835-1. Online ahead of print.
2026
Dual function of ERH in primary miRNA biogenesis
Simon Aschenwald,
Aswini K Panda,
Theresa Wurzer,
Sonja Baumgärtner,
Valerie S Ertl,
Jakob Hatzer,
Andreas Villunger,
Sebastian Falk,
Sebastian Herzog.
Nucleic Acids Res. 2026 Jun 22;54(12):gkag601. doi: 10.1093/nar/gkag601.
2026
Comparative insights into the apoptosome, inflammasomes and PIDDosome
Mohamed Lamkanfi,
Lieselotte Vande Walle,
Felix Eichin,
Andreas Villunger.
Nat Rev Immunol. 2026 May 6. doi: 10.1038/s41577-026-01304-3. Online ahead of print.
2026
What does BCL-2 do? From new molecular insights to the clinical implications
Carlo M Croce,
Stephen W G Tait,
Ana J Garcia-Sáez,
Andreas Villunger,
Anthony Letai,
Harriet S Walter,
Martin J S Dyer,
Douglas R Green,
Yufang Shi,
Gerry Melino.
Cell Death Differ. 2026 Apr;33(4):673-693. doi: 10.1038/s41418-025-01607-3. Epub 2026 Feb 19.
2026
The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development
M Leone,
N Kinz,
F Eichin,
D Obwegs,
V C Sladky,
V Z Braun,
R Hirschberger,
D Rizzotto,
L Englmaier,
C Manzl,
K Moos,
J Mergner,
P Giansanti,
N Martinez-Garcia,
M M Marques,
E D Jacotot,
L Eblahed,
R Yousif,
M K Wright,
D Dawood,
L S Maupome,
C Savko,
M Boerries,
M A Sussman,
A Villunger.
Cell Death Differ. 2026 Jun;33(6):1292-1304. doi: 10.1038/s41418-025-01645-x. Epub 2026 Jan 12.
2026
Limited roles of the miR-17-92 cluster in the regulation of T-cell apoptosis
Katharina Hoppe,
Johannes Woelk,
Julia Benz,
Sarah Spoeck,
William J Olson,
Andreas Villunger,
Natascha Hermann-Kleiter,
Verena Labi.
FEBS J. 2026 May;293(10):2845-2861. doi: 10.1111/febs.70387. Epub 2026 Jan 6.
2026
Mitotic errors as triggers of cell death and inflammation
Dario Rizzotto,
Christian Zierhut,
Andreas Villunger.
Nat Cell Biol. 2026 Jan;28(1):21-34. doi: 10.1038/s41556-025-01785-9. Epub 2026 Jan 6.
2025
WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2
Jordan C J Wilson,
JiaYi Zhu,
Vanesa Vinciauskaite,
Eloise G Lloyd,
Simon Lam,
Alexandra Hart,
Chen Gang Goh,
Fadia Bou-Dagher,
Hlib Razumkov,
Lena Kobel,
Zacharias Kontarakis,
John Fielden,
Moritz F Schlapansky,
Joanna I Loizou,
Andreas Villunger,
Jacob E Corn,
Giulia Biffi,
Glenn R Masson,
Stefan J Marciniak,
Aldo S Bader,
Stephen P Jackson.
Nat Commun. 2025 Oct 9;16(1):8983. doi: 10.1038/s41467-025-64050-5.
2025
Mitotic lethality prevents inflammation
Christian Zierhut,
Andreas Villunger.
Nat Cell Biol. 2025 Jan;27(1):7-8. doi: 10.1038/s41556-024-01529-1.
