Publications
2026
The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development
M Leone,
N Kinz,
F Eichin,
D Obwegs,
V C Sladky,
V Z Braun,
R Hirschberger,
D Rizzotto,
L Englmaier,
C Manzl,
K Moos,
J Mergner,
P Giansanti,
N Martinez-Garcia,
M M Marques,
E D Jacotot,
L Eblahed,
R Yousif,
M K Wright,
D Dawood,
L S Maupome,
C Savko,
M Boerries,
M A Sussman,
A Villunger.
Cell Death Differ. 2026 Jan 12. doi: 10.1038/s41418-025-01645-x. Online ahead of print.
2026
Limited roles of the miR-17-92 cluster in the regulation of T-cell apoptosis
Katharina Hoppe,
Johannes Woelk,
Julia Benz,
Sarah Spoeck,
William J Olson,
Andreas Villunger,
Natascha Hermann-Kleiter,
Verena Labi.
FEBS J. 2026 Jan 6. doi: 10.1111/febs.70387. Online ahead of print.
2026
Mitotic errors as triggers of cell death and inflammation
Dario Rizzotto,
Christian Zierhut,
Andreas Villunger.
Nat Cell Biol. 2026 Jan;28(1):21-34. doi: 10.1038/s41556-025-01785-9. Epub 2026 Jan 6.
2025
WEE1 inhibitors synergise with mRNA translation defects via activation of the kinase GCN2
Jordan C J Wilson,
JiaYi Zhu,
Vanesa Vinciauskaite,
Eloise G Lloyd,
Simon Lam,
Alexandra Hart,
Chen Gang Goh,
Fadia Bou-Dagher,
Hlib Razumkov,
Lena Kobel,
Zacharias Kontarakis,
John Fielden,
Moritz F Schlapansky,
Joanna I Loizou,
Andreas Villunger,
Jacob E Corn,
Giulia Biffi,
Glenn R Masson,
Stefan J Marciniak,
Aldo S Bader,
Stephen P Jackson.
Nat Commun. 2025 Oct 9;16(1):8983. doi: 10.1038/s41467-025-64050-5.
2025
Mitotic lethality prevents inflammation
Christian Zierhut,
Andreas Villunger.
Nat Cell Biol. 2025 Jan;27(1):7-8. doi: 10.1038/s41556-024-01529-1.
2024
Global analysis of endogenous protein disorder in cells
Shouxiang Zhang,
Tze Cin Owyong,
Oana Sanislav,
Lukas Englmaier,
Xiaojing Sui,
Geqing Wang,
David W Greening,
Nicholas A Williamson,
Andreas Villunger,
Jonathan M White,
Begoña Heras,
Wallace W H Wong,
Paul R Fisher,
Yuning Hong.
Nat Methods. 2025 Jan;22(1):124-134. doi: 10.1038/s41592-024-02507-z. Epub 2024 Nov 25.
2024
Caspase-2 kills cells with extra centrosomes
Dario Rizzotto,
Vincenza Vigorito,
Patricia Rieder,
Filip Gallob,
Gian Mario Moretta,
Claudia Soratroi,
Joel S Riley,
Florian Bellutti,
Stefano Li Veli,
Alessia Mattivi,
Michael Lohmüller,
Sebastian Herzog,
Beat C Bornhauser,
Etienne D Jacotot,
Andreas Villunger,
Luca L Fava.
Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30.
2024
Centrioles are frequently amplified in early B cell development but dispensable for humoral immunity
Marina A Schapfl,
Gina M LoMastro,
Vincent Z Braun,
Maretoshi Hirai,
Michelle S Levine,
Eva Kiermaier,
Verena Labi,
Andrew J Holland,
Andreas Villunger.
Nat Commun. 2024 Oct 15;15(1):8890. doi: 10.1038/s41467-024-53222-4.
2024
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses
Jana Trifinopoulos,
Julia List,
Thorsten Klampfl,
Klara Klein,
Michaela Prchal-Murphy,
Agnieszka Witalisz-Siepracka,
Florian Bellutti,
Luca L Fava,
Gerwin Heller,
Sarah Stummer,
Patricia Testori,
Monique L Den Boer,
Judith M Boer,
Sonja Marinovic,
Gregor Hoermann,
Wencke Walter,
Andreas Villunger,
Piotr Sicinski,
Veronika Sexl,
Dagmar Gotthardt.
Haematologica. 2025 Apr 1;110(4):877-892. doi: 10.3324/haematol.2024.285701. Epub 2024 Oct 10.
2024
Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3
Maja Zupančič,
Erik Keimpema,
Evgenii O Tretiakov,
Stephanie J Eder,
Itamar Lev,
Lukas Englmaier,
Pradeep Bhandari,
Simone A Fietz,
Wolfgang Härtig,
Estelle Renaux,
Andreas Villunger,
Tomas Hökfelt,
Manuel Zimmer,
Frédéric Clotman,
Tibor Harkany.
Nat Commun. 2024 Oct 5;15(1):8631. doi: 10.1038/s41467-024-52762-z.
