Publications
2019
The Tubulin Detyrosination Cycle: Function andEnzymes.
Nieuwenhuis J,
Brummelkamp TR.
Trends Cell Biol. 2019 Jan;29(1):80-92. doi: 10.1016/j.tcb.2018.08.003. Epub 2018 Sep 10. Review.
2018
Viral escape from endosomes and host detection at a glance.
Staring J,
Raaben M,
Brummelkamp TR.
J Cell Sci. 2018 Aug 3;131(15). pii: jcs216259. doi: 10.1242/jcs.216259. Review. .
2018
The Tubulin Detyrosination Cycle: Function and Enzymes.
Nieuwenhuis J,
Brummelkamp TR.
Trends Cell Biol. 2018 Sep 10. pii: S0962-8924(18)30141-7. doi: 10.1016/j.tcb.2018.08.003. [Epub ahead of print] Review.
2018
KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.
Staring J,
van den Hengel LG,
Raaben M,
Blomen VA,
Carette JE,
Brummelkamp TR.
Cell Host Microbe. 2018 May 9;23(5):636-643.e5. doi: 10.1016/j.chom.2018.03.019. Epub 2018 Apr 19.
2017
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J,
von Castelmur E,
Blomen VA,
van den Hengel LG,
Brockmann M,
Baggen J,
Thibaut HJ,
Nieuwenhuis J,
Janssen H,
van Kuppeveld FJ,
Perrakis A,
Carette JE,
Brummelkamp TR.
Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11.
2017
Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.
Brockmann M,
Blomen VA,
Nieuwenhuis J,
Stickel E,
Raaben M,
Bleijerveld OB,
Altelaar AFM,
Jae LT,
Brummelkamp TR.
Nature. 2017 Jun 8;546(7657):307-311. doi: 10.1038/nature22376. Epub 2017 May 31.
2017
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.
Mezzadra R,
Sun C,
Jae LT,
Gomez-Eerland R,
de Vries E,
Wu W,
Logtenberg MEW,
Slagter M,
Rozeman EA,
Hofland I,
Broeks A,
Horlings HM,
Wessels LFA,
Blank CU,
Xiao Y,
Heck AJR,
Borst J,
Brummelkamp TR,
Schumacher TNM.
Nature. 2017 Sep 7;549(7670):106-110. doi: 10.1038/nature23669. Epub 2017 Aug 16.
2017
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
Loregger A,
Raaben M,
Tan J,
Scheij S,
Moeton M,
van den Berg M,
Gelberg-Etel H,
Stickel E,
Roitelman J,
Brummelkamp T,
Zelcer N.
Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7.
2017
NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.
Raaben M,
Jae LT,
Herbert AS,
Kuehne AI,
Stubbs SH,
Chou YY,
Blomen VA,
Kirchhausen T,
Dye JM,
Brummelkamp TR,
Whelan SP.
Cell Host Microbe. 2017 Nov 8;22(5):688-696.e5. doi: 10.1016/j.chom.2017.10.002.
2015
Gene essentiality and synthetic lethality in haploid human cells.
Blomen VA,
Májek P,
Jae LT,
Bigenzahn JW,
Nieuwenhuis J,
Staring J,
Sacco R,
van Diemen FR,
Olk N,
Stukalov A,
Marceau C,
Janssen H,
Carette JE,
Bennett KL,
Colinge J,
Superti-Furga G,
Brummelkamp TR.
Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15.