DE EN

Sylvia Knapp

The innate immune response to bacterial infections

Publications

2013

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes.

Warszawska JM, Gawish R, Sharif O, Sigel S, Doninger B, Lakovits K, Mesteri I, Nairz M, Boon L, Spiel A, Fuhrmann V, Strobl B, Müller M, Schenk P, Weiss G, Knapp S.
J Clin Invest. 2013 August 1; 123(8).
2013

The scavenger receptor CD36 downmodulates the early inflammatory response while enhancing bacterial phagocytosis during pneumococcal pneumonia.

Sharif O, Matt U, Saluzzo S, Lakovits K, Haslinger I, Furtner T, Doninger B, Knapp S.
J Immunol. 2013 Jun 1;190(11):5640-8. doi: 10.4049/jimmunol.1202270. Epub 2013 Apr 22.
2013

WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs.

Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits A, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, Bochkov VN, Scott JD, Knapp S.
J Clin Invest. 2013 July 1; 123(7): 3014–3024. .
2012

Apolipoprotein B100 is a suppressor of Staphylococcus aureus-induced innate immune response in humans and mice.

Sigel S, Bunk S, Meergans T, Doninger B, Stich K, Stulnig T, Derfler K, Hoffmann J, Deininger S, von Aulock S, Knapp S.
Eur J Immunol. 2012 Jul 18. doi: 10.1002/eji.201242564. [Epub ahead of print].
2012

Animal Models of Sepsis.

Knapp S.
Section Editor of this issue and Editorial. Drug Discovery Today – Disease Models Jan 2012.
2011

TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo.

Zivkovic A, Sharif O, Stich K, Doninger B, Biaggio M, Colinge J, Bilban M, Mesteri I, Hazemi P, Lemmens-Gruber R, Knapp S.
J Immunol. 2011 Feb 1;186(3):1608-17.
2011

Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.

Gratz N, Hartweger H, Matt U, Kratochvill F, Janos M, Sigel S, Drobits B, Li XD, Knapp S, Kovarik P.
PLoS Pathog. 2011 May;7(5):e1001345.
2010

CD14 is a co-receptor of Toll-like receptors 7 and 9.

Baumann CL, Aspalter IM, Sharif O, Pichlmair A, Bluml S, Grebien F, Bruckner M, Pasierbek P, Aumayr K, Planyavsky M, Bennett KL, Colinge J, Knapp S, Superti-Furga G.
J Exp Med. 2010 Nov 22;207(12):2689-701. Epub 2010 Nov 15.
2010

Tyrosine kinase 2 controls interleukin-1 production at the translational level.

Radwan M, Stiefvater R, Gruner T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B.
J Immunol. 2010 Sep 15;185(6):3544-53. Epub 2010 Aug 16.