Publications
2015
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
Li J,
Klughammer J,
Farlik M,
Penz T,
Spittler A,
Barbieux C,
Berishvili E,
Bock C,
Kubicek S.
EMBO Rep. 2016 Feb. Epub 2015 Dec 21.
2015
Differential DNA Methylation Analysis without a Reference Genome.
Klughammer J,
Datlinger P,
Printz D,
Sheffield NC,
Farlik M,
Hadler J,
Fritsch G,
Bock C.
Cell Rep. 2015 Dec 7. pii: S2211-1247(15)01324-8. doi: 10.1016/j.celrep.2015.11.024.
2015
ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors.
Schmidl C,
Rendeiro AF,
Sheffield NC,
Bock C.
Nat Methods. 2015 Aug 17. doi: 10.1038/nmeth.3542.
2015
LOLA: Enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor.
Sheffield NC,
Bock C.
Bioinformatics. 2015 Oct 27. pii: btv612.
2015
Whole exome sequencing identifies novel MPL and JAK2 mutations in triple negative myeloproliferative neoplasms.
Milosevic Feenstra JD,
Nivarthi H,
Gisslinger H,
Leroy E,
Rumi E,
Chachoua I,
Bagienski K,
Kubesova B,
Pietra D,
Gisslinger B,
Milanesi C,
Jäger R,
Chen D,
Berg T,
Schalling M,
Schuster M,
Bock C,
Constantinescu SN,
Cazzola M,
Kralovics R.
Blood. 2015 Sep 30. pii: blood-2015-07-661835.
2015
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation.
Licciardello MP,
Müllner MK,
Dürnberger G,
Kerzendorfer C,
Boidol B,
Trefzer C,
Sdelci S,
Berg T,
Penz T,
Schuster M,
Bock C,
Kralovics R,
Superti-Furga G,
Colinge J,
Nijman SM,
Kubicek S.
Oncogene. 2015 Jul;34(29):3780-90. doi: 10.1038/onc.2014.319. Epub 2014 Sep 29.
2015
Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1.
Tomazou EM,
Sheffield NC,
Schmidl C,
Schuster M,
Schönegger A,
Datlinger P,
Kubicek S,
Bock C,
Kovar H.
Cell Rep. 2015 Feb 24;10(7):1082-95. doi: 10.1016/j.celrep.2015.01.042. Epub 2015 Feb 19.
2015
KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia.
Malinowska-Ozdowy K,
Frech C,
Schönegger A,
Eckert C,
Cazzaniga G,
Stanulla M,
Zur Stadt U,
Mecklenbräuker A,
Schuster M,
Kneidinger D,
von Stackelberg A,
Locatelli F,
Schrappe M,
Horstmann MA,
Attarbaschi A,
Bock C,
Mann G,
Haas OA,
Panzer-Grümayer R.
Leukemia. 2015 Apr 28. doi: 10.1038/leu.2015.107.
2015
Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics.
Farlik M,
Sheffield NC,
Nuzzo A,
Datlinger P,
Schönegger A,
Klughammer J,
Bock C.
Cell Rep. 2015 Mar 3;10(8):1386-97. doi: 10.1016/j.celrep.2015.02.001. Epub 2015 Feb 26.
2015
Improving reference epigenome catalogs by computational prediction.
Ebert P,
Bock C.
Nat Biotechnol. 2015 Apr;33(4):354-5. doi: 10.1038/nbt.3194.