Publications
2017
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.
Licciardello MP,
Ringler A,
Markt P,
Klepsch F,
Lardeau CH,
Sdelci S,
Schirghuber E,
Müller AC,
Caldera M,
Wagner A,
Herzog R,
Penz T,
Schuster M,
Boidol B,
Dürnberger G,
Folkvaljon Y,
Stattin P,
Ivanov V,
Colinge J,
Bock C,
Kratochwill K,
Menche J,
Bennett KL,
Kubicek S.
Nat Chem Biol. 2017 Jul;13(7):771-778. doi: 10.1038/nchembio.2382. Epub 2017 May 22.
2017
2017 ISCB Overton Prize: Christoph Bock.
Fogg CN,
Kovats DE,
Berger B.
F1000Res. 2017 Jun 26;6. pii: ISCB Comm J-999. doi: 10.12688/f1000research.11586.1. eCollection 2017.
2017
Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.
Andergassen D,
Dotter CP,
Wenzel D,
Sigl V,
Bammer PC,
Muckenhuber M,
Mayer D,
Kulinski TM,
Theussl HC,
Penninger JM,
Bock C,
Barlow DP,
Pauler FM,
Hudson QJ.
Elife. 2017 Aug 14;6. pii: e25125. doi: 10.7554/eLife.25125.
2017
A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.
Göschl L,
Preglej T,
Hamminger P,
Bonelli M,
Andersen L,
Boucheron N,
Gülich AF,
Müller L,
Saferding V,
Mufazalov IA,
Hirahara K,
Seiser C,
Matthias P,
Penz T,
Schuster M,
Bock C,
Waisman A,
Steiner G,
Ellmeier W.
J Autoimmun. 2017 Sep 27. pii: S0896-8411(17)30595-4. doi: 10.1016/j.jaut.2017.09.008. [Epub ahead of print]
2017
Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Moder M,
Velimezi G,
Owusu M,
Mazouzi A,
Wiedner M,
Ferreira da Silva J,
Robinson-Garcia L,
Schischlik F,
Slavkovsky R,
Kralovics R,
Schuster M,
Bock C,
Ideker T,
Jackson SP,
Menche J,
Loizou JI.
Nat Commun. 2017 Nov 1;8(1):1238. doi: 10.1038/s41467-017-01439-x.
2016
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity, Cell 2017 Jan 12 (epub ahead of print 2016 Dec 1);168(1), 86-100.
Li J,
Casteels T,
Frogne T,
Ingvorsen C,
Honoré C,
Courtney M,
Huber KVM,
Schmitner N,
Kimmel RA,
Romanov RA,
Sturtzel C,
Lardeau CH,
Klughammer J,
Farlik M,
Sdelci S,
Vieira A,
Avolio F,
Briand F,
Baburin I,
Májek P,
Pauler FM,
Penz T,
Stukalov A,
Gridling M,
Parapatics K,
Barbieux C,
Berishvili E,
Spittler A,
Colinge J,
Bennett KL,
Hering S,
Sulpice T,
Bock C,
Distel M,
Harkany T,
Meyer D,
Superti-Furga G,
Collombat P,
Hecksher-Sørensen J,
and Kubicek S.
doi:10.1016/j.cell.2016.11.010. Abstract: http://www.cell.com/cell/abstract/S0092-8674(16)31531-8
2016
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Sdelci S,
Lardeau CH,
Tallant C,
Klepsch F,
Klaiber B,
Bennett J,
Rathert P,
Schuster M,
Penz T,
Fedorov O,
Superti-Furga G,
Bock C,
Zuber J,
Huber KV,
Knapp S,
Müller S,
Kubicek S.
Nat Chem Biol. 2016 May 9. doi: 10.1038/nchembio.2080.
2016
Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr-/- mice.
Jeurissen ML,
Walenbergh SM,
Houben T,
Gijbels MJ,
Li J,
Hendrikx T,
Oligschlaeger Y,
van Gorp PJ,
Binder CJ,
Donners MM,
Shiri-Sverdlov R.
Atherosclerosis. 2016 Oct 20;255:59-65. doi: 10.1016/j.atherosclerosis.2016.10.038
2016
DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation.
Farlik M,
Halbritter F,
Müller F,
Choudry FA,
Ebert P,
Klughammer J,
Farrow S,
Santoro A,
Ciaurro V,
Mathur A,
Uppal R,
Stunnenberg HG,
Ouwehand WH,
Laurenti E,
Lengauer T,
Frontini M,
Bock C.
Cell Stem Cell. 2016 Dec 1;19(6):808-822. doi: 10.1016/j.stem.2016.10.019.
2016
Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.
Ilott NE,
Bollrath J,
Danne C,
Schiering C,
Shale M,
Adelmann K,
Krausgruber T,
Heger A,
Sims D,
Powrie F.
ISME J. 2016 Oct;10(10):2389-404. doi: 10.1038/ismej.2016.40.
